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4-(2-Bromoethyl)benzonitrile

4-(2-Bromoethyl)benzonitrile Structure
4-(2-Bromoethyl)benzonitrile structure
CAS No.
72054-56-9
Chemical Name:
4-(2-Bromoethyl)benzonitrile
Synonyms
4-Cyanophenethyl bromide;p-Cyanophenethyl bromide;p-(2-Bromoethyl)benzonitrile;4-(2-Bromoethyl)benzonitrile;Benzonitrile, 4-(2-bromoethyl)-
CBNumber:
CB42489586
Molecular Formula:
C9H8BrN
Molecular Weight:
210.07
MDL Number:
MFCD12025077
MOL File:
72054-56-9.mol
MSDS File:
SDS
Last updated:2026-05-28 01:59:24
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4-(2-Bromoethyl)benzonitrile Properties

Melting point 53-54℃
Boiling point 290℃
Density 1.43
Flash point 129℃
storage temp. Sealed in dry,Room Temperature
form solid
Appearance White to off-white Solid
InChI 1S/C9H8BrN/c10-6-5-8-1-3-9(7-11)4-2-8/h1-4H,5-6H2
InChIKey NNNRGWOWXNCGCV-UHFFFAOYSA-N
SMILES BrCCC1=CC=C(C#N)C=C1
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2926907090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

4-(2-Bromoethyl)benzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR45144 4-(2-Bromoethyl)benzonitrile >99% 72054-56-9 100mg $21 2026-06-04 Buy
Apolloscientific OR45144 4-(2-Bromoethyl)benzonitrile >99% 72054-56-9 250mg $24 2026-06-04 Buy
Apolloscientific OR45144 4-(2-Bromoethyl)benzonitrile >99% 72054-56-9 1g $40 2026-06-04 Buy
Apolloscientific OR45144 4-(2-Bromoethyl)benzonitrile >99% 72054-56-9 5g $52 2026-06-04 Buy
Apolloscientific OR45144 4-(2-Bromoethyl)benzonitrile >99% 72054-56-9 25g $213 2026-06-04 Buy
Product number Packaging Price Buy
OR45144 100mg $21 Buy
OR45144 250mg $24 Buy
OR45144 1g $40 Buy
OR45144 5g $52 Buy
OR45144 25g $213 Buy

4-(2-Bromoethyl)benzonitrile Chemical Properties,Uses,Production

Synthesis

4-(2-HYDROXYETHYL)BENZONITRILE

69395-13-7

4-(2-Bromoethyl)benzonitrile

72054-56-9

General procedure for the synthesis of 4-(2-bromoethyl)benzonitrile from 4-(2-hydroxyethyl)benzonitrile: to a stirred solution of 4-(2-hydroxyethyl)benzonitrile (1.0 g, 6.8 mmol, 1.0 eq.) in dichloromethane (DCM, 20 mL) was added sequentially carbon tetrabromide (CBr4, 4.5016 g, 13.6 mmol, 2.0 eq.) and triphenylphosphine (TPP, 3.835 g, 13.6 mmol, 2.0 equiv). The reaction mixture was stirred at room temperature for 5 hours and the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was diluted with water and extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated. The crude product was purified by column chromatography to afford pure 4-(2-bromoethyl)benzonitrile (1.3 g, 91% yield). The results of liquid chromatography-mass spectrometry (LC-MS, Method 23): retention time (Rt) = 2.01 min; mass-to-charge ratio (m/z) = 210.05 ([M+H]+).

References

[1] Patent: WO2018/149986, 2018, A1. Location in patent: Page/Page column 95
[2] Pharmazie, 1982, vol. 37, # 1, p. 13 - 16
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 1, p. 65 - 68
[4] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979, p. 1128 - 1132
[5] Patent: US5811459, 1998, A

4-(2-Bromoethyl)benzonitrile Preparation Products And Raw materials

Raw materials

Benzaldehyde, 4-(2-bromoethyl)- 4-(2-Hydroxyethyl)benzonitrile Triphenylphosphine Carbon tetrabromide Dichloromethane

Preparation Products

4-(2-Amino-ethyl)-benzoic acid

4-(2-Bromoethyl)benzonitrile Suppliers

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
SynAsst Chemical. 021-60343070 China 12731 55
Nanjing ShengSai Chemical Co., Ltd. 025-85205967 13951876367 shengsaichem@163.com China 818 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai CR Corporation Limited 13917420128 13062833949 fred.wen@crcorporation.cn China 9774 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58
Supplier Advantage
SynAsst Chemical. 55
Nanjing ShengSai Chemical Co., Ltd. 58
Bide Pharmatech Ltd. 60
Cool Pharm, Ltd 58
Changzhou Anxuan Chemical, Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Shanghai CR Corporation Limited 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Aikon International Limited 58

View Lastest Price from 4-(2-Bromoethyl)benzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-Bromoethyl)benzonitrile pictures 2020-01-05 4-(2-Bromoethyl)benzonitrile
72054-56-9
 $9.80 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

4-(2-Bromoethyl)benzonitrile Spectrum

4-(2-Bromoethyl)benzonitrile(72054-56-9)1HNMR
4-(2-Bromoethyl)benzonitrile 4-Cyanophenethyl bromide p-(2-Bromoethyl)benzonitrile p-Cyanophenethyl bromide Benzonitrile, 4-(2-bromoethyl)- 72054-56-9