Unii-8163770L8p
- CAS No.
- 769901-96-4
- Chemical Name:
- Unii-8163770L8p
- Synonyms
- Capeserod;Unii-8163770L8p;5-(8-Amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-3-(1-phenethylpiperidin-4-yl)-1,3,4-oxad;5-(5-amino-6-chloro-2,3-dihydro-1,4-benzodioxin-8-yl)-3-[1-(2-phenylethyl)piperidin-4-yl]-1,3,4-oxadiazol-2-one;5-(8-Amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-3-(1-phenethylpiperidin-4-yl)-1,3,4-oxadiazol-2(3H)-one;5-(8-AMINO-7-CHLORO-2,3-DIHYDRO-1,4-BENZODIOXIN-5-YL)-3-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]-1,3,4-OXADIAZOL-2(3H)-ONE;1,3,4-Oxadiazol-2(3H)-one, 5-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-[1-(2-phenylethyl)-4-piperidinyl]-
- CBNumber:
- CB42492030
- Molecular Formula:
- C23H25ClN4O4
- Molecular Weight:
- 456.92
- MDL Number:
- MFCD12827991
- MOL File:
- 769901-96-4.mol
- MSDS File:
- SDS
| Boiling point | 584.4±60.0 °C(Predicted) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| pka | 8.58±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 8163770L8P |
Unii-8163770L8p price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1051961 | Capeserod 98.66% | 769901-96-4 | 1mg | $260 | 2026-06-04 | Buy |
| ChemScene | CS-1051961 | Capeserod 98.66% | 769901-96-4 | 5mg | $650 | 2026-06-04 | Buy |
| ChemScene | CS-1051961 | Capeserod 98.66% | 769901-96-4 | 10mg | $937 | 2026-06-04 | Buy |
| Biorbyt Ltd | orb1944840 | Capeserod 99.94% | 769901-96-4 | 1mg | $240 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1944840 | Capeserod 99.94% | 769901-96-4 | 5mg | $530 | 2026-05-06 | Buy |
Unii-8163770L8p Chemical Properties, Uses, Production
Uses
Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a Ki of 0.6 nM for 5-HT4 receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models[1].
IC 50
5-HT4 Receptor: 0.6 nM (Ki)
References
[1] Tamburella A, et al., Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: behavioral and neurochemical studies in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Oct 1;33(7):1205-10. DOI:10.1016/j.pnpbp.2009.07.001
Unii-8163770L8p Preparation Products And Raw materials
Raw materials
Preparation Products
Unii-8163770L8p Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
