Vicriviroc Malate
- CAS No.
- 541503-81-5
- Chemical Name:
- Vicriviroc Malate
- Synonyms
- CS-599;Vicriviroc Malate;1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine malate
- CBNumber:
- CB42537571
- Molecular Formula:
- C32H44F3N5O7
- Molecular Weight:
- 667.7162696
- MDL Number:
- MFCD14635362
- MOL File:
- 541503-81-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Vicriviroc Malate price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FV104295 | Vicriviroc malate | 541503-81-5 | 2mg | $649 | 2026-06-04 | Buy |
| Biosynth | FV104295 | Vicriviroc malate | 541503-81-5 | 5mg | $1103.3 | 2026-06-04 | Buy |
| Biosynth | FV104295 | Vicriviroc malate | 541503-81-5 | 10mg | $2076.8 | 2026-06-04 | Buy |
| Biosynth | FV104295 | Vicriviroc malate | 541503-81-5 | 25mg | $2985.5 | 2026-06-04 | Buy |
| ChemScene | CS-0093575 | Vicriviroc malate | 541503-81-5 | 1mg | $429 | 2026-06-04 | Buy |
Vicriviroc Malate Chemical Properties, Uses, Production
Uses
Vicriviroc (SCH 417690) malate is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc malate can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer[1][2].
Definition
ChEBI: (4,6-Dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone;2-hydroxybutanedioic acid is a member of (trifluoromethyl)benzenes.
target
CCR5
References
[1] Strizki JM, et al. Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2005;49(12):4911-4919. DOI:10.1128/AAC.49.12.4911-4919.2005
[2] Bessudo A, et al. Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab in Patients With Advanced or Metastatic Microsatellite Stable Colorectal Cancer. Clin Colorectal Cancer. 2024;23(3):285-294. DOI:10.1016/j.clcc.2024.05.003
Vicriviroc Malate Preparation Products And Raw materials
Raw materials
Preparation Products
Vicriviroc Malate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1941 | 55 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| Shanghai Huikai Chemical Technology Co., Ltd. | 021-61995394 18916691159 | chemicalsea@163.com | China | 1970 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2981 | 60 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9739 | 58 |
