ChemicalBook >> CAS DataBase List >>5-BroMo-1H-pyrazolo[4,3-b]pyridine

5-BroMo-1H-pyrazolo[4,3-b]pyridine

5-BroMo-1H-pyrazolo[4,3-b]pyridine structure

CAS No.: 1227628-78-5

Chemical Name:: 5-BroMo-1H-pyrazolo[4,3-b]pyridine

Synonyms: 5-broMo-1H-pyrazolo[4;5-BroMo-1H-pyrazolo[4,3-b...;5-BroMo-1H-pyrazolo[4,3-b]pyridine;1H-Pyrazolo[4,3-b]pyridine, 5-bromo-;5-Bromo-1H-pyrazolo[4,3-b]pyridine

CBNumber:: CB42597201

Molecular Formula:: C6H4BrN3

Molecular Weight:: 198.02

MDL Number:: MFCD15526714

MOL File:: 1227628-78-5.mol

MSDS File:: SDS

Last updated:2026-05-28 03:14:29

Request For Quotation

5-BroMo-1H-pyrazolo[4,3-b]pyridine Properties

Boiling point	351.7±22.0 °C(Predicted)
Density	1.894±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	solid
pka	9.68±0.40(Predicted)
Appearance	White to light yellow Solid
InChI	InChI=1S/C6H4BrN3/c7-6-2-1-4-5(9-6)3-8-10-4/h1-3H,(H,8,10)
InChIKey	QWLXNBNVCRSNEX-UHFFFAOYSA-N
SMILES	C12C=NNC1=CC=C(Br)N=2
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22
HS Code	2933998090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral

5-BroMo-1H-pyrazolo[4,3-b]pyridine price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	BLN00049	5-Bromo-1H-pyrazolo[4,3-b]pyridine Aldrich	1227628-78-5	1g	$1490	2026-04-30	Buy
Apolloscientific	OR933142	5-Bromo-1H-pyrazolo[4,3-b]pyridine 98%	1227628-78-5	250mg	$37	2026-06-04	Buy
Apolloscientific	OR933142	5-Bromo-1H-pyrazolo[4,3-b]pyridine 98%	1227628-78-5	1g	$58	2026-06-04	Buy
Apolloscientific	OR933142	5-Bromo-1H-pyrazolo[4,3-b]pyridine 98%	1227628-78-5	5g	$215	2026-06-04	Buy
Apolloscientific	OR933142	5-Bromo-1H-pyrazolo[4,3-b]pyridine 98%	1227628-78-5	25g	$748	2026-06-04	Buy

Product number	Packaging	Price	Buy
BLN00049	1g	$1490	Buy
OR933142	250mg	$37	Buy
OR933142	1g	$58	Buy
OR933142	5g	$215	Buy
OR933142	25g	$748	Buy

5-BroMo-1H-pyrazolo[4,3-b]pyridine Chemical Properties, Uses, Production

Synthesis

22282-96-8

110-46-3

1227628-78-5

To a stirred chloroform solution of 6-bromo-2-methyl-3-nitropyridine (5 g, 26.73 mmol) was added potassium acetate (3.14 g, 32.08 mmol) and acetic anhydride (10.9 g, 106 mmol) sequentially at 10 °C. The reaction mixture was stirred at 65 °C for 2 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was cooled to room temperature, followed by the addition of isoamyl nitrite (3.75 g, 32.06 mmol) dropwise over 15 minutes and 18-crown-6 (0.7 g, 2.67 mmol). The reaction mixture was continued to be stirred at 65 °C for 16 h. The progress of the reaction was likewise monitored by TLC. At the end of the reaction, it was cooled to room temperature and 120 mL of a mixture of methanol and water (1:1 volume ratio) was added to the reaction mixture, followed by the addition of potassium carbonate (34.48 g, 24.99 mmol) and potassium hydroxide (4.2 g, 74.97 mmol). The mixture was stirred at room temperature for 3 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and the organic layer was separated and washed sequentially with water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 5-bromo-1H-pyrazolo[4,3-b]pyridine (5 g) as an off-white solid.

References

[1] Patent: US2016/347717, 2016, A1. Location in patent: Paragraph 0595; 0596

5-BroMo-1H-pyrazolo[4,3-b]pyridine Preparation Products And Raw materials

Raw materials

2-Bromo-5-nitro-6-picoline Isoamyl nitrite Methanol Potassium carbonate Potassium hydroxide

Acetic anhydride Chloroform Potassium Acetate Water 18-Crown-6

1of2

Preparation Products

5-BroMo-1H-pyrazolo[4,3-b]pyridine Suppliers

Global Suppliers ( 98)

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Qihang Biotechnology Co., Ltd	18151111370		China	8587	58
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
ZEROSCHEM.CO.,LTD.	10-61256048 13810278579;	sales@zeroschem.com	China	1401	59
Changzhou Wanyao Biotechnology Co., Ltd.	0519-89185693 15312551983	2410037592@qq.com	China	278	55
Wuhan ariel chemical Co., LTD.	18986259541 18986259541	sales@3stc.com	China	3821	58
Wuhan TCASChem Technology Co., Ltd.	027-86697669 13986148687	sales@tcaschem.com	China	3994	55
Shanghai Jian Chao Chemical Technology Co., Ltd.	150-2103-5486 18017383231	983544897@qq.com	China	9335	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Suzhou Laing Biological Technology Co., LTD	0512-62968256 18550502935	export@laingbiotec.com	China	992	58
3A SpeedChemical Inc	21-65679720	service@speedchemical.com	China	604	55

Supplier	Advantage
Suzhou Qihang Biotechnology Co., Ltd	58
Adamas Reagent, Ltd.	59
ZEROSCHEM.CO.,LTD.	59
Changzhou Wanyao Biotechnology Co., Ltd.	55
Wuhan ariel chemical Co., LTD.	58
Wuhan TCASChem Technology Co., Ltd.	55
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
Bide Pharmatech Ltd.	60
Suzhou Laing Biological Technology Co., LTD	58
3A SpeedChemical Inc	55

View Latest Price from 5-BroMo-1H-pyrazolo[4,3-b]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-25	5-Bromo-1H-pyrazolo[4,3-b]pyridine 1227628-78-5	$1.10-9.90	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2020-01-10	5-BroMo-1H-pyrazolo[4,3-b]pyridine 1227628-78-5	$1.00	1KG	99%	200kg	Career Henan Chemical Co

5-Bromo-1H-pyrazolo[4,3-b]pyridine
1227628-78-5
$1.10-9.90
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

5-BroMo-1H-pyrazolo[4,3-b]pyridine
1227628-78-5
$1.00
99%
Career Henan Chemical Co

5-BroMo-1H-pyrazolo[4,3-b]pyridine Spectrum

5-BroMo-1H-pyrazolo[4,3-b]pyridine(1227628-78-5)¹HNMR

1227628-78-5 (5-BroMo-1H-pyrazolo[4,3-b]pyridine) Related Search:

5-bromo-1H-pyrazolo[3,4-c]pyridine Methyl 5-bromo-1H-imidazole-4-carboxylate 5,7-Dibromo-1H-pyrazolo[4,3-b]pyridine 5-Bromo-3-methyl-1H-pyrazolo[4,3-b]pyridine 6-Bromo-1H-pyrazolo[4,3-b]pyridine

1H-Pyrazolo[4,3-b]pyridine, 5,6-dibromo-

1of2

5-BroMo-1H-pyrazolo[4,3-b]pyridine 5-broMo-1H-pyrazolo[4 5-BroMo-1H-pyrazolo[4,3-b... 1H-Pyrazolo[4,3-b]pyridine, 5-bromo- 5-Bromo-1H-pyrazolo[4,3-b]pyridine 1227628-78-5