Methyl 4-aMino-3-(MethylaMino)benzoate
- CAS No.
- 616224-38-5
- Chemical Name:
- Methyl 4-aMino-3-(MethylaMino)benzoate
- Synonyms
- Methyl 4-aMino-3-(MethylaMino)benzoate;Methyl 4-amino-3-(methylamino)benzoate - [M71835];Benzoic acid, 4-amino-3-(methylamino)-, methyl ester
- CBNumber:
- CB42651822
- Molecular Formula:
- C9H12N2O2
- Molecular Weight:
- 180.2
- MDL Number:
- MFCD15144544
- MOL File:
- 616224-38-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H312-H315-H302-H332 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P302+P352-P321-P332+P313-P362 |
Methyl 4-aMino-3-(MethylaMino)benzoate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM140014 | Methyl 4-amino-3-(methylamino)benzoate | 616224-38-5 | 50mg | $900 | 2026-06-04 | Buy |
| Biosynth | FM140014 | Methyl 4-amino-3-(methylamino)benzoate | 616224-38-5 | 500mg | $900 | 2026-06-04 | Buy |
| Biosynth | FM140014 | Methyl 4-amino-3-(methylamino)benzoate | 616224-38-5 | 250mg | $900 | 2026-06-04 | Buy |
| Biosynth | FM140014 | Methyl 4-amino-3-(methylamino)benzoate | 616224-38-5 | 100mg | $900 | 2026-06-04 | Buy |
| Biosynth | FM140014 | Methyl 4-amino-3-(methylamino)benzoate | 616224-38-5 | 1000mg | $900 | 2026-06-04 | Buy |
Methyl 4-aMino-3-(MethylaMino)benzoate Chemical Properties, Uses, Production
Synthesis
251643-13-7
616224-38-5
General procedure for the synthesis of methyl 4-amino-3-(methylamino)benzoate from methyl 3-(methylamino)-4-nitrobenzoate: at 0 °C, an aqueous sodium bisulfite solution (17.4 g, 100 mmol, dissolved in 80 mL of water) was slowly added to methyl-3-(methylamino)-4-nitrobenzoate (855 mg, 4.75 mmol) containing a tetrahydrofuran (70 mL) and ethanol (30 mL) in a mixed solution. The reaction solution was transformed from an orange solution to an orange suspension. The reaction mixture was stirred at room temperature for 2 hours, during which time the color of the suspension gradually changed from orange to yellow. Subsequently, saturated sodium bicarbonate solution (100 mL) was added, at which point the suspension further changed to colorless. The reaction mixture was extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with brine (30 mL) and dried over anhydrous magnesium sulfate. After filtration, the organic phase was concentrated and dried under high vacuum to afford methyl 4-amino-3-(methylamino)benzoate (586 mg, 68% yield) as a yellow oily product. After standing for 10 min, the oily material started to crystallize. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 2.89 (s, 3H), 3.37-3.81 (m, 2H), 3.85 (s, 3H), 6.67 (d, J = 8.01 Hz, 1H), 7.33 (d, J = 1.37 Hz, 1H), 7.44 (dd, J = 8.11,1.66 Hz, 1H).
References
[1] Patent: WO2005/80388, 2005, A1. Location in patent: Page/Page column 89
[2] Patent: US2018/170908, 2018, A1. Location in patent: Paragraph 0416
[3] Patent: US2011/130398, 2011, A1. Location in patent: Page/Page column 72
[4] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 18
[5] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 38; 39
Methyl 4-aMino-3-(MethylaMino)benzoate Preparation Products And Raw materials
Methyl 4-aMino-3-(MethylaMino)benzoate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Hangzhou Molcore Biopharmatech Co.,Ltd | 400-711-5280 86-571-81025280 | sales@molcore.com | China | 9957 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Suzhou Nuoouman Biological Technology Co., Ltd. | 15026866316 | 180642609@qq.com | China | 4966 | 58 |
| Shanghai HongMin Pharmaceutical Co., Ltd. | 13651987816 | hongminpharm@163.com | China | 2338 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
