BroModifluoroMethyl phenyl sulfone
- CAS No.
- 80351-58-2
- Chemical Name:
- BroModifluoroMethyl phenyl sulfone
- Synonyms
- BroModifluoroMethyl phenyl sulfone;Bromodifluoromethanesulfonylbenzene;[(bromodifluoromethyl)sulfonyl]benzene;Benzene, [(bromodifluoromethyl)sulfonyl]-
- CBNumber:
- CB42709701
- Molecular Formula:
- C7H5BrF2O2S
- Molecular Weight:
- 271.08
- MDL Number:
- MFCD22628354
- MOL File:
- 80351-58-2.mol
- MSDS File:
- SDS
| Melting point | 33-34 °C |
|---|---|
| Boiling point | 291.8±40.0 °C(Predicted) |
| Density | 1.745±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C7H5BrF2O2S/c8-7(9,10)13(11,12)6-4-2-1-3-5-6/h1-5H |
| InChIKey | VYNTWHUALGNGNU-UHFFFAOYSA-N |
| SMILES | C1(S(C(Br)(F)F)(=O)=O)=CC=CC=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P302+P352-P362+P364 |
| Safety Statements | 24/25 |
| HS Code | 29309090 |
BroModifluoroMethyl phenyl sulfone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B802018-50MG | Bromodifluoromethyl Phenyl Sulfone | 80351-58-2 | 50mg | $84 | 2026-06-03 | Buy |
| TRC | TRC-B802018-25MG | Bromodifluoromethyl Phenyl Sulfone | 80351-58-2 | 25mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-B802018-250MG | Bromodifluoromethyl Phenyl Sulfone | 80351-58-2 | 250mg | $358 | 2026-06-03 | Buy |
| Biosynth | FDA35158 | Bromodifluoromethanesulfonylbenzene | 80351-58-2 | 250mg | $312.5 | 2026-06-04 | Buy |
| Biosynth | FDA35158 | Bromodifluoromethanesulfonylbenzene | 80351-58-2 | 2.5g | $1150.5 | 2026-06-04 | Buy |
BroModifluoroMethyl phenyl sulfone Chemical Properties, Uses, Production
Description
The nucleophilic reactions of bromodifluoromethyl phenyl sulfone with electrophiles such as aldehydes in the presence of TDAE affords (phenylsulfonyl)difluoromethyl-containing synthetically useful intermediates. Palladium-mediated reactions of styrene derivatives, vinyl ethers, and heteroaromatics with bromodifluoromethyl phenyl sulfone in the presence of potassium carbonate affords the (phenylsulfonyl)difluoromethylated products.
Uses
Bromodifluoromethyl phenyl sulfone is an intermediate component in the synthesis of (phenylsulfonyl)difluoromethyl and can be used to prepare (phenylsulfonyl)difluoromethylated products by palladium-mediated reactions.
Uses
Bromodifluoromethyl Phenyl Sulfone can be used to prepare difluoromethyl ethers via difluoromethylation of alcohols.
Reactions
(1) Difluoromethylation of aldehydes.
(2) Difluoromethylation of styrenes, vinyl ethers, and heteroaromatics.
References
[1] G.K. SURYA PRAKASH . Nucleophilic difluoromethylation and difluoromethylenation using bromodifluoromethyl phenyl sulfone[J]. Journal of Fluorine Chemistry, 2005. DOI:10.1016/j.jfluchem.2005.07.011.
[2] NAKIN SURAPANICH. ChemInform Abstract: Palladium-Mediated Heck-Type Reactions of [(Bromodifluoromethyl)sulfonyl]benzene: Synthesis of α-Alkenyl- and α-Heteroaryl-Substituted α,α-Difluoromethyl Phenyl Sulfones.[J]. ChemInform, 2013. DOI:10.1002/chin.201314090.
BroModifluoroMethyl phenyl sulfone Preparation Products And Raw materials
BroModifluoroMethyl phenyl sulfone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANG FLUORO | 021-65170832 15601903708 | qinba_1@163.com | China | 401 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD | 571-89189769 15168342188 | China | 228 | 62 | |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9957 | 58 |
| Greenherbs Science and Technology Development Co., Ltd. | 010-61136123 | pub02@greenherbs.com.cn | China | 4045 | 58 |
| JinJin Le Chemical Co., Ltd | 18001959627(微信同号) 18001959627 | jjlchem2@163.com | China | 9890 | 58 |
| Jiaxing Deyi Chemical Co., Ltd. | 86-0573-85866609 18367600069 | 945717149@qq.com | China | 9506 | 58 |
View Latest Price from BroModifluoroMethyl phenyl sulfone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Difluoromethyl sulfonylbenzene
80351-58-2
|
99.99% | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd | |||
 |
2025-04-04 | BroModifluoroMethyl phenyl sulfone
80351-58-2
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
||
 |
2020-02-21 | BroModifluoroMethyl phenyl sulfone
80351-58-2
|
$8.00 | 1g | ＞98% HPLC | Career Henan Chemical Co |
-
- Difluoromethyl sulfonylbenzene
80351-58-2
- $0.10
- 99.99%
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- BroModifluoroMethyl phenyl sulfone
80351-58-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- BroModifluoroMethyl phenyl sulfone
80351-58-2
- $8.00
- ＞98% HPLC
- Career Henan Chemical Co
