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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate

CAS No.
82692-93-1
Chemical Name:
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
Synonyms
TOOS;Trinder Reagent;TOOS, SODIUM SALT;TOOS extrapure, 98%;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE;N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT;Peroxidase/Hydrogen Peroxide Detection , Colorimetry;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO;N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT;SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE
CBNumber:
CB4279813
Molecular Formula:
C12H20NNaO4S
Molecular Weight:
297.34
MDL Number:
MFCD00040641
MOL File:
82692-93-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-02 13:10:26

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Properties

storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Solid
color White to Almost white
BRN 5689521
InChI InChI=1S/C12H19NO4S.Na.H/c1-3-13(8-12(14)9-18(15,16)17)11-6-4-5-10(2)7-11;;/h4-7,12,14H,3,8-9H2,1-2H3,(H,15,16,17);;
InChIKey IRQRBVOQGUPTLG-UHFFFAOYSA-M
SMILES N(C1C=CC=C(C)C=1)(CC)CC(O)CS(O)(=O)=O.[NaH]
CAS DataBase Reference 82692-93-1(CAS DataBase Reference)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
3
HS Code  29214200
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E8631 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt for enzymic, spectrophotometric det. of H 82692-93-1 1g $258 2026-04-30 Buy
Sigma-Aldrich 04340 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt for enzymic, spectrophotometric determination of H 82692-93-1 500mg $111 2026-04-30 Buy
TCI Chemical S0805 Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate >98.0%(HPLC) 82692-93-1 1g $33 2026-04-30 Buy
TCI Chemical S0805 Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate >98.0%(HPLC) 82692-93-1 5g $94 2026-04-30 Buy
Usbiological 274762 N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline Sodium Salt Dihydrate (TOOS) ≥99%(HPLC) 82692-93-1 10g $347 2026-06-03 Buy
Product number Packaging Price Buy
E8631 1g $258 Buy
04340 500mg $111 Buy
S0805 1g $33 Buy
S0805 5g $94 Buy
274762 10g $347 Buy

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Chemical Properties, Uses, Production

Description

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used in the enzymatic photometric determination of hydrogen peroxide. This compound is a widely studied small molecule inhibitor in scientific research. Originally synthesized in the early 1980s, it has since found extensive use in various investigations into cellular processes. It has its inhibition of the Na+/H+ exchanger (NHE), which is a membrane protein crucial for regulating intracellular pH. Additionally, EIPA has shown its potential as an inhibitor of TRPV channels, which play a role in pain sensation and thermoregulation. Another significant finding indicates Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate′s inhibition of the Na+/Ca2+ exchanger (NCX), responsible for regulating intracellular calcium levels.

Chemical Properties

White crystalline powder

Uses

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1].

References

[1] Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647. DOI:10.1016/j.talanta.2021.122647

126-83-0
102-27-2
82692-93-1
Synthesis of Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate from Sodium 3-Chloro-2-hydroxypropanesulfonate and N-Ethyl-3-methylaniline

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Preparation Products And Raw materials

Global Suppliers ( 305)
Supplier Tel Email Country ProdList Advantage
Hubei New Desheng Materials Technology Co., Ltd. 0711-3702650 18971041571 vickyzhao@whdschem.com China 57 58
Wuhan Xinzhecheng Technology Co., Ltd 17720588118 2442693357@qq.com China 144 58
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd. 18671296875 1205035102@qq.com China 4300 58
WuHan Difu Biotechnology Co.Ltd +86-18008681304 18008681304 898948847@qq.com China 20 58
Suzhou BEC Biological Technology Co., Ltd +86-512-68095917 17712685869 sales@bek.com.cn China 142 59
Chongqing Yuen Technology Co., Ltd. 13883023934; 13883023934 yesnkj@163.com China 63 58
Suzhou yacoo science co.,Ltd 0512-87182055 13451648594 sales@yacoo.com.cn China 4576 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84

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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate pictures 2026-09-17 Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
1KG 99% 3500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate pictures 2026-09-02 Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
1KG 98 1000 KG Shaanxi Dideu New Materials Co. Ltd
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate pictures 2026-07-15 Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
1KG 99% 2000KG Wuhan Fortuna Chemical Co.,Ltd

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Spectrum

3-(N-ETHYL-M-TOLUIDINO)-2-HYDROXYPROPANE-SULFONIC ACID SODIUM SALT 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUM SALT 3-(n-ethyl-3-methylanilino)-2-hydroxypropansulf.acidso-salt 3-[ethyl(3-methylphenyl)amino]-2-hydroxy-1-propanesulfonicacimonosodiums N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE SODIUM SALT N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-TOLUIDINE SODIUM SALT TOOS, SODIUM SALT SodiuM 3-[Ethyl(M-tolyl)aMino]-2-hydroxy-1-propanesulfonate  3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt 3-(N-ethyl-Methylanilino)-2-hydroxy Propane sulfonic acid, SodiuM Salt 3-(Ethyl(M-tolyl)aMino)-2-hydroxypropane-1-sulfonic acid, sodiuM salt Sodium 3-(ethyl(m-tolyl)amino)-2-hydroxypropane-1-sulfonate 3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Sodium N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine TOOS N-ethyl-N-(2-hydroxy-3-sulfonatopropyl)-3-methylaniline sodium salt Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfote SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline sodium salt Peroxidase/Hydrogen Peroxide Detection , Colorimetry Trinder Reagent SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE TOOS N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt (N=1) TOOS (3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUMSALT) N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE,SODIUMSALT(TOOS) N-Ethyl-N-sulphohydroxypropyl-m-toluidine, sodium salt >98% N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate, Sodium N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine, TOOS, N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt, 3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt TOOS (3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline sodium 3-(N-ethyl-Methylanilino)-2-hydroxy propane sulfonic acid, SodiuM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline,sodiumsalt,dihydrate 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANSULF.ACIDSODIUMSALT 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt ,99% 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt,3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt, N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt, So Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate> N-Ethyl-N-sulfohydroxypropyl-m-toluidine sodium salt (TOOS) 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt monohydrate TOOS extrapure, 98% 3-(N-ethyl-methylanilino)-2-hydroxy Propane sulfonic acid, Sodium Salt(TOOS) 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt TOOS Sodium Salt (3- (N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic Acid Sodium Salt ) odium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate TOOS N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine,sodium salt (TOOS) 82692-93-1 C12H18NaO4S C12H18NNaO4SxH2O C12H20NNaO5S Biochemicals and Reagents Analytical Standards Alphabetic Analytical Chromatography Product Catalog