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Sucrose octaacetate

Sucrose octaacetate Structure
Sucrose octaacetate structure
CAS No.
126-14-7
Chemical Name:
Sucrose octaacetate
Synonyms
Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
CBNumber:
CB4296191
Molecular Formula:
C28H38O19
Molecular Weight:
678.59
MDL Number:
MFCD00006623
MOL File:
126-14-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-30 11:39:11
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Sucrose octaacetate Properties

Melting point 82-85 °C(lit.)
Boiling point 260 °C(lit.)
alpha D25.4 +58.5° (c = 2.56 in abs alcohol)
Density 1.28
refractive index 60 ° (C=2, EtOH)
FEMA 3038 | SUCROSE OCTAACETATE
FLAVIS Number 16.081 | Sucrose octaacetate
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Powder
color White to creamy white
Odor odorless
Odor Type odorless
optical activity [α]22/D +58.8°, c = 2.5 in ethanol
Water Solubility SLIGHTLY SOLUBLE
Merck 14,8881
BRN 79290
Major Application flavors and fragrances
Cosmetics Ingredients Functions DENATURANT
FRAGRANCE
InChIKey ZIJKGAXBCRWEOL-SAXBRCJISA-N
SMILES CC(=O)OC[C@H]1O[C@H](O[C@]2(COC(C)=O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
LogP 3.19
CAS DataBase Reference 126-14-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) SUCROSE OCTAACETATE
FDA 21 CFR 175.105
EWG's Food Scores 1
FDA UNII 07V591057T
NIST Chemistry Reference Sucrose, octaacetate(126-14-7)
EPA Substance Registry System Sucrose octaacetate (126-14-7)
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-37/39-26
WGK Germany  2
RTECS  WN6620000
F  3
TSCA  TSCA listed
HS Code  29400090
Storage Class 11 - Combustible Solids
Toxicity LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg
REACH Registrations Active

Sucrose octaacetate price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 1 each $58 2026-04-30 Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 1kg $111 2026-04-30 Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 10Kg $707 2026-04-30 Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 25kg $1260 2026-04-30 Buy
Sigma-Aldrich 8.22144 D-(+)-Saccharose octaacetate for synthesis 126-14-7 250g $64.4 2026-04-30 Buy
Product number Packaging Price Buy
W303801 1 each $58 Buy
W303801 1kg $111 Buy
W303801 10Kg $707 Buy
W303801 25kg $1260 Buy
8.22144 250g $64.4 Buy

Sucrose octaacetate Chemical Properties,Uses,Production

Chemical Properties

white to creamy white powder

Chemical Properties

Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.

Chemical Properties

Sucrose octaacetate is odorless with an intensly bitter flavor influenced by food acids

Uses

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide

Uses

Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.

Uses

Adhesive; impregnating and insulating papers; in lacquers and plastics; as a denaturant for alcohol.

Production Methods

Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.

Definition

ChEBI: Sucrose octaacetate is a glycoside.

Preparation

May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.

Pharmaceutical Applications

Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.

Safety Profile

Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.

Safety

Sucrose octaacetate is generally regarded as safe. It is considered slightly hazardous in cases of skin contact (irritant), ingestion, or inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg

storage

Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.

Purification Methods

After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]

Regulatory Status

GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.

Sucrose octaacetate Preparation Products And Raw materials

Raw materials

Sucrose Pyridine

Preparation Products

Sucrose octaacetate Suppliers

Global( 429)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Fengtai Biotechnology Co., Ltd. 0531-0531-82066716 15662658391 528732991@qq.com China 1064 58
inhua City Baikang Biological Engineering Co., LTD 0573-15557365800 15557365800 78117547@qq.com China 509 58
Nantong Tianxiang Bioengineering Co., Ltd 0513-5666452 15152885778 475035221@qq.com China 1073 58
Hebei Qiansheng Biotechnology Co., Ltd 13068769255 13068769255 3865144208@qq.com China 756 58
Qingdao Qingshan Bioengineering Co., Ltd 15336405941 3956832176@qq.com China 831 58
Jiangsu Dongju Biotechnology Co. , Ltd. 15152114979 2805239892@qq.com China 519 58
Shandong Tangzheng Biotechnology Co., Ltd 15318846974 3999356010@qq.com China 834 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Supplier Advantage
Shandong Fengtai Biotechnology Co., Ltd. 58
inhua City Baikang Biological Engineering Co., LTD 58
Nantong Tianxiang Bioengineering Co., Ltd 58
Hebei Qiansheng Biotechnology Co., Ltd 58
Qingdao Qingshan Bioengineering Co., Ltd 58
Jiangsu Dongju Biotechnology Co. , Ltd. 58
Shandong Tangzheng Biotechnology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81

Related articles

View Lastest Price from Sucrose octaacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sucrose octaacetate pictures 2026-09-12 Sucrose octaacetate
126-14-7
 0.99 RongNa Biotechnology Co.,Ltd
Sucrose octaacetate pictures 2026-09-11 Sucrose octaacetate
126-14-7
 1kg/Bag ≥98% 50 T/Month Hebei Qujie Technology Co., Ltd.
Sucrose octaacetate pictures 2026-09-11 Sucrose octaacetate
126-14-7
 $66.00-99.00 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Sucrose octaacetate Spectrum

Sucrose octaacetate(126-14-7)MSSucrose octaacetate(126-14-7)1HNMRSucrose octaacetate(126-14-7)13CNMRSucrose octaacetate(126-14-7)IR1Sucrose octaacetate(126-14-7)Raman

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OCTA-O-ACETYL D-(+)-SACCHAROSE OCTA-O-ACETYL D-(+)-SUCROSE Sucrose octa actate SUCROSE OCTAACETATE 97+% OCTAACETYL SUCROSE(SACCHAROSE OCTAACETATE) D-SucroseOctoacetate,>99% D-SucroseOctoacetate SUCROSEOCTAACETATE,NF SUCROSE OCTACETATE D-(+)-Sucrose octaacetate, Sucrose octaacetate [(2S,3S,4R,5R)-4-Acetyloxy-2,5-bis(acetyloxymethyl)-2-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoxolan-3-yl] acetate 2,3,4,6,1',3',4',6'-Octa-O-acetylsucrose a-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-b-D-fructofuranosyl, tetraacetate Octa-O-acetylsucrose 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl α-D-glucopyranoside 2,3,4,6-tetraacetate 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl-α-D-glucopyranoside 2,3,4,6-tetraacetate β-D-Fructofuranosyl α-D-glucopyranoside octaacetate Sucrose octaacetate,98% Sucrose octaacetate Sucrose Octaacetate (500 mg) D-(+)-Saccharose Octaacetate Octa-O-acetyl D-(+)-Saccharose D-(+)-Sucrose Octaacetate Sucrose OCLaacetate (2R,3R,4S,5R,6R)-2-(acetoxyMethyl)-6-(((2S,3S,4R,5R)-3,4-diacetoxy-2,5-bis(acetoxyMethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate Octa-O-acetyl D-(+)-Surcose a-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-b-D-fructofuranosyl, 2,3,4,6-tetraacetate D-(+)-Saccharose octaacetate for synthesis Sucrose octaacetateOCTAACETATE OCTAACETYLSUCROSE SACCHAROSE OCTAACETATE .alpha.-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-.beta.-D-fructofuranosyl,tetraacetate 1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl-alpha-d-glucopyranosidtetr 1,3,4,6-Tetra-O-acetylhex-2-ulofuranosyl 2,3,4,6-tetra-O-acetylhexopyranoside aacetate alpha-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-beta-D-fructofuranosyl, tetraacetate alpha-d-glucopyranoside,1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl,tetra Soa D-(+)-SACCHAROSE OCTAACETATE D-SACCHAROSE OCTAACETATE D-(+)-SUCROSE OCTAACETATE Octa-O-acetyl D-(+)-Sucrose > Octa D α-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-β-D-fructofuranosyl, 2,3,4,6-tetraacetate Sucrose octaacetate USP/EP/BP 204-772-1 High Purity Best Price Sucrose Octaacetate CAS 126-14-7 with Best Price Sucrose octaacetate(USP/NF/CP2020) bitter taste Octa-O-acetyl D-(+)-Sucrose, ≥ 98.0% Sucrose Octaacetatee Sucrose Octaacetate(USP/NF/ChP) Sucrose octaacetate, 10 mM in DMSO Bittering agent (Sucrose octaacetate) D-(+)-Sucrose octaacetate FEMA 3038 Sucrose Octaacetate, food grade 126-14-7 124-14-7 C28H38O19