5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
- CAS No.
- 7630-74-2
- Chemical Name:
- 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
- Synonyms
- dehydronuciferin;Dehydronuciferine;ehydronuciferine;videoconferencing;dehydronuciferinene;Dehydronuciferine, 10 mM in DMSO;1,2-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline;5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline;4H-Dibenzo[de,g]quinoline, 5,6-dihydro-1,2-dimethoxy-6-methyl-;5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline USP/EP/BP
- CBNumber:
- CB43038422
- Molecular Formula:
- C19H19NO2
- Molecular Weight:
- 293.36
- MDL Number:
- MFCD32200961
- MOL File:
- 7630-74-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 493.0±45.0 °C(Predicted) |
|---|---|
| Density | 1.193±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 4.04±0.20(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| InChI | InChI=1S/C19H19NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,10-11H,8-9H2,1-3H3 |
| InChIKey | JBGSWIBJAGBGOP-UHFFFAOYSA-N |
| SMILES | N1(C)C2=C3C(C(OC)=C(OC)C=C3CC1)=C1C=CC=CC1=C2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310+P330-P405-P501 |
5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0032561 | Dehydronuciferine 98.10% | 7630-74-2 | 1mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-0032561 | Dehydronuciferine 98.10% | 7630-74-2 | 5mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0032561 | Dehydronuciferine 98.10% | 7630-74-2 | 10mg | $433 | 2026-06-04 | Buy |
| ChemScene | CS-0032561 | Dehydronuciferine 98.10% | 7630-74-2 | 25mg | $737 | 2026-06-04 | Buy |
| ChemScene | CS-0032561 | Dehydronuciferine 98.10% | 7630-74-2 | 50mg | $1040 | 2026-06-04 | Buy |
5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Chemical Properties, Uses, Production
Uses
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL[1].
Definition
ChEBI: Dehydronuciferine is an isoquinoline alkaloid.
Synthesis
The preparation process for total alkaloid extracts from lotus leaves generally comprises the following steps: (1) Extraction: The solvent employed may be water or any alcohol, ketone, or ester solvent; a mixed solvent composed of these solvents in specific proportions; or acidic or alkaline solvents formulated by combining these solvents with acids or alkalis. The preferred extraction method involves adding 30C90% ethanol to lotus leaf material, followed by reflux extraction for 2C3 cycles, each lasting 1C2 hours, with a solvent volume of 15C30 times the material weight (L/kg). (2) Filtration: Includes methods such as centrifugation, vacuum filtration, ultrafiltration, and pressure filtration, with or without the use of any one or a combination of the following clarifying agents: alcohol precipitants, gelatin, kaolin, various resins, polyethylene glycol, polyethylene triol, chitosan, and commercial natural clarifying agents such as 101 Juice Clarifier or ZTC+1 Natural Clarifier. (3) Concentration: Includes thin-film evaporation, rotary evaporation, and decoction concentration under atmospheric or reduced pressure conditions. (4) Drying: Includes vacuum drying, spray drying, and freeze drying. The composition of active alkaloid constituents from lotus leaves is extracted and prepared from the dried leaves of Nelumbonum nectariniflorum Gaertn., containing multiple alkaloid active components. These alkaloids primarily include lotus leaf alkaloid, N-demethyl lotus leaf alkaloid, O-demethyl lotus leaf alkaloid, saponin alkaloid, lotus alkaloid, lotus leaf alkaloid, N-demethylamaphylline, 2-hydroxy-1-methoxyapomorphine, amaphylline, N-methylisohengzhouwuyaoine, N-methylhengzhouwuyaoine, dehydrohepenine, dehydrolotusine, and other derivatives based on their parent nucleus.
References
[1] Yang, et al. Synthesis and structure-activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors. Medicinal Chemistry Research June 2014, Volume 23, Issue 6, pp 3178–3186
5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Shanghai ChengShao Biological Technology Co., Ltd. | 021-61847300 13341622919 | shcss01@163.com | China | 4806 | 58 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 4999 | 58 |
| Shanghai Uteam Biotechnology Co., Ltd. | 021-36031160 13311776681 | 3338195766@QQ.com | China | 5091 | 55 |
| Shanghai Biological Technology Development Co., Ltd. | 021-69955236-807 13918189704 | chinaruji@chinaruji.com | China | 5093 | 55 |
View Latest Price from 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-27 | Dehydronuciferine
7630-74-2
|
$65.00-283.00 | 99.53% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2020-01-10 | 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
7630-74-2
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-

- Dehydronuciferine
7630-74-2
- $65.00-283.00
- 99.53%
- TargetMol Chemicals Inc.
-
![5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/8bc99468-0952-462c-b2a2-9c76546d4ce8.jpg)
- 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
7630-74-2
- $9.80
- ≥98%
- Career Henan Chemical Co





