ChemicalBook >> CAS DataBase List >>5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline

CAS No.
7630-74-2
Chemical Name:
5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
Synonyms
dehydronuciferin;Dehydronuciferine;ehydronuciferine;videoconferencing;dehydronuciferinene;Dehydronuciferine, 10 mM in DMSO;1,2-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline;5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline;4H-Dibenzo[de,g]quinoline, 5,6-dihydro-1,2-dimethoxy-6-methyl-;5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline USP/EP/BP
CBNumber:
CB43038422
Molecular Formula:
C19H19NO2
Molecular Weight:
293.36
MDL Number:
MFCD32200961
MOL File:
7630-74-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Properties

Boiling point 493.0±45.0 °C(Predicted)
Density 1.193±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 4.04±0.20(Predicted)
form Solid
color Light yellow to yellow
InChI InChI=1S/C19H19NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,10-11H,8-9H2,1-3H3
InChIKey JBGSWIBJAGBGOP-UHFFFAOYSA-N
SMILES N1(C)C2=C3C(C(OC)=C(OC)C=C3CC1)=C1C=CC=CC1=C2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310+P330-P405-P501

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0032561 Dehydronuciferine 98.10% 7630-74-2 1mg $130 2026-06-04 Buy
ChemScene CS-0032561 Dehydronuciferine 98.10% 7630-74-2 5mg $282 2026-06-04 Buy
ChemScene CS-0032561 Dehydronuciferine 98.10% 7630-74-2 10mg $433 2026-06-04 Buy
ChemScene CS-0032561 Dehydronuciferine 98.10% 7630-74-2 25mg $737 2026-06-04 Buy
ChemScene CS-0032561 Dehydronuciferine 98.10% 7630-74-2 50mg $1040 2026-06-04 Buy
Product number Packaging Price Buy
CS-0032561 1mg $130 Buy
CS-0032561 5mg $282 Buy
CS-0032561 10mg $433 Buy
CS-0032561 25mg $737 Buy
CS-0032561 50mg $1040 Buy

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Chemical Properties, Uses, Production

Uses

Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL[1].

Definition

ChEBI: Dehydronuciferine is an isoquinoline alkaloid.

Synthesis

The preparation process for total alkaloid extracts from lotus leaves generally comprises the following steps: (1) Extraction: The solvent employed may be water or any alcohol, ketone, or ester solvent; a mixed solvent composed of these solvents in specific proportions; or acidic or alkaline solvents formulated by combining these solvents with acids or alkalis. The preferred extraction method involves adding 30C90% ethanol to lotus leaf material, followed by reflux extraction for 2C3 cycles, each lasting 1C2 hours, with a solvent volume of 15C30 times the material weight (L/kg). (2) Filtration: Includes methods such as centrifugation, vacuum filtration, ultrafiltration, and pressure filtration, with or without the use of any one or a combination of the following clarifying agents: alcohol precipitants, gelatin, kaolin, various resins, polyethylene glycol, polyethylene triol, chitosan, and commercial natural clarifying agents such as 101 Juice Clarifier or ZTC+1 Natural Clarifier. (3) Concentration: Includes thin-film evaporation, rotary evaporation, and decoction concentration under atmospheric or reduced pressure conditions. (4) Drying: Includes vacuum drying, spray drying, and freeze drying. The composition of active alkaloid constituents from lotus leaves is extracted and prepared from the dried leaves of Nelumbonum nectariniflorum Gaertn., containing multiple alkaloid active components. These alkaloids primarily include lotus leaf alkaloid, N-demethyl lotus leaf alkaloid, O-demethyl lotus leaf alkaloid, saponin alkaloid, lotus alkaloid, lotus leaf alkaloid, N-demethylamaphylline, 2-hydroxy-1-methoxyapomorphine, amaphylline, N-methylisohengzhouwuyaoine, N-methylhengzhouwuyaoine, dehydrohepenine, dehydrolotusine, and other derivatives based on their parent nucleus.

References

[1] Yang, et al. Synthesis and structure-activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors. Medicinal Chemistry Research June 2014, Volume 23, Issue 6, pp 3178–3186

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 99)
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shandong Xiya Chemical Co., Ltd. 4009903999 13395398332 sales@xiyashiji.com China 20788 60
Shanghai ChengShao Biological Technology Co., Ltd. 021-61847300 13341622919 shcss01@163.com China 4806 58
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 4999 58
Shanghai Uteam Biotechnology Co., Ltd. 021-36031160 13311776681 3338195766@QQ.com China 5091 55
Shanghai Biological Technology Development Co., Ltd. 021-69955236-807 13918189704 chinaruji@chinaruji.com China 5093 55

View Latest Price from 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dehydronuciferine pictures 2026-07-27 Dehydronuciferine
7630-74-2
$65.00-283.00 99.53% 10g TargetMol Chemicals Inc.
5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline pictures 2020-01-10 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
7630-74-2
$9.80 1KG ≥98% 20 tons Career Henan Chemical Co

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Spectrum

5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline 1,2-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline dehydronuciferinene 4H-Dibenzo[de,g]quinoline, 5,6-dihydro-1,2-dimethoxy-6-methyl- 5,6-Dihydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline USP/EP/BP videoconferencing ehydronuciferine Dehydronuciferine, 10 mM in DMSO Dehydronuciferine dehydronuciferin 7630-74-2