Azido-PEG6-PFP ester
- CAS No.
- 1818294-47-1
- Chemical Name:
- Azido-PEG6-PFP ester
- Synonyms
- N3-PEG6-CH2CH2COOPFP;Azido-PEG6-PFP ester;Perfluorophenyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate;(2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- CBNumber:
- CB43062368
- Molecular Formula:
- C21H28F5N3O8
- Molecular Weight:
- 545.46
- MDL Number:
- MFCD26793784
- MOL File:
- 1818294-47-1.mol
Azido-PEG6-PFP ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114775 | Azido-PEG6-PFP ester ≥98% | 1818294-47-1 | 250mg | $186 | 2026-06-04 | Buy |
| ChemScene | CS-0114775 | Azido-PEG6-PFP ester ≥98% | 1818294-47-1 | 1g | $500 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1166 | Azido-PEG6-PFP ester 98% | 1818294-47-1 | 100mg | $569 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1166 | Azido-PEG6-PFP ester 98% | 1818294-47-1 | 250mg | $908 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1166 | Azido-PEG6-PFP ester 98% | 1818294-47-1 | 1g | $1887 | 2026-06-04 | Buy |
Azido-PEG6-PFP ester Chemical Properties, Uses, Production
Description
Azido-PEG6-PFP ester is a a high purity PEG linker containing azide and PFP ester moities. The azide can participate in Click Chemistry reactions with alkynes, such as DBCO and BCN to form triazole groups. The PFP ester is amine-reactive and is less susceptible toward hydrolysis compared to NHS ester.
Uses
Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG6-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39866 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
