5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one
![5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one Structure](CAS/20180702/GIF/99898-84-7.gif)
- CAS No.
- 99898-84-7
- Chemical Name:
- 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one
- Synonyms
- 5-chloropyrazolo<1,5-a>pyrimidin-7-one;5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one;Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-chloro-
- CBNumber:
- CB43065415
- Molecular Formula:
- C6H4ClN3O
- Molecular Weight:
- 169.57
- MDL Number:
- MOL File:
- 99898-84-7.mol
- MSDS File:
- SDS
| Melting point | 298-300 °C (decomp) |
|---|---|
| Boiling point | 302.4±52.0 °C(Predicted) |
| Density | 1.71±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -2.58±0.40(Predicted) |
| form | solid |
| Appearance | White to off-white Solid |
| InChI | 1S/C6H4ClN3O/c7-4-3-6(11)10-5(9-4)1-2-8-10/h1-3,9H |
| InChIKey | QNNBWYYLICBZOI-UHFFFAOYSA-N |
| UNSPSC Code | 12352101 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 1 Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | ZDA89884 | 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one | 99898-84-7 | 0.5g | $324.5 | 2026-06-05 | Buy |
| Biosynth | ZDA89884 | 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one | 99898-84-7 | 5g | $1239 | 2026-06-05 | Buy |
| Matrix Scientific | 304383 | 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one | 99898-84-7 | 250.00mg | $65 | 2026-05-19 | Buy |
| Matrix Scientific | 304383 | 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one | 99898-84-7 | 1.00g | $184 | 2026-05-19 | Buy |
| Matrix Scientific | 304383 | 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one | 99898-84-7 | 5.00g | $724 | 2026-05-19 | Buy |
5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one Chemical Properties, Uses, Production
Synthesis
![5,7-DICHLOROPYRAZOLO[1,5-A]PYRIMIDINE](/CAS/GIF/57489-77-7.gif)
57489-77-7
![5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one](/CAS/20180702/GIF/99898-84-7.gif)
99898-84-7
General procedure for the synthesis of 5-chloropyrazolo[1,5-a]pyrimidin-7(1H)-ones from 5,7-dichloropyrazolo[1,5-a]pyrimidines: 1 g of 5,7-dichloropyrazolo[1,5-a]pyrimidines was suspended in 25 mL of 1 N aqueous sodium hydroxide solution, heated to 90 °C and stirred for 0.5 h. The reaction was carried out by thin layer chromatography (TLC). The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the reaction mixture was cooled to room temperature. The pH was adjusted to 2 with 1N HCl solution to form a suspension. 5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one (0.9 g, 99% yield) was obtained by filtration after standing.
References
[1] Patent: CN107033149, 2017, A. Location in patent: Paragraph 0110; 0180-0181
[2] Journal of Heterocyclic Chemistry, 1985, vol. 22, # 3, p. 601 - 634
5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one Preparation Products And Raw materials
5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Santai Labs, Inc. | 519-85601385 | marketing@santailabs.com | China | 891 | 62 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Yujinpharma(Tianjin) Technology Co.,Ltd. | 13370351217 kungfu1217@1 | kungfu1217@163.com | China | 7994 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 3905209149@qq.com | China | 9711 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Hebei Weite Medical Technology Co., Ltd | 13180081292 13180081292 | contact@wetogethermed.com | China | 7707 | 58 |
