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methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

CAS No.
890839-11-9
Chemical Name:
methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate
Synonyms
methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate;Benzeneacetic acid, α-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
CBNumber:
CB43073575
Molecular Formula:
C16H23BO4
Molecular Weight:
290.16
MDL Number:
MOL File:
890839-11-9.mol
MSDS File:
SDS
Last updated:2026-05-28 02:53:07

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 312810 Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 890839-11-9 100.00mg $62 2026-05-19 Buy
Matrix Scientific 312810 Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 890839-11-9 250.00mg $106 2026-05-19 Buy
Matrix Scientific 312810 Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 890839-11-9 1.00g $284 2026-05-19 Buy
Synthonix M58819 Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 97% 890839-11-9 100mg $60 2026-05-06 Buy
Synthonix M58819 Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 97% 890839-11-9 250mg $110 2026-05-06 Buy
Product number Packaging Price Buy
312810 100.00mg $62 Buy
312810 250.00mg $106 Buy
312810 1.00g $284 Buy
M58819 100mg $60 Buy
M58819 250mg $110 Buy

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Chemical Properties, Uses, Production

Synthesis

Iodomethane

74-88-4

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate

890839-11-9

b) General procedure for the synthesis of methyl 2-(4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate: under argon protection, a THF solution of methyl 2-(4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate (1.04 g, 3.78 mmol) ( 3.5 mL, 1.5 M) was added dropwise to THF (6 mL), keeping the reaction temperature at -78 °C. After the dropwise addition, the reaction mixture was slowly warmed up to 0 °C, followed by the addition of iodomethane (3.22 g, 22.6 mmol). The reaction mixture was stirred at room temperature for 1 h. The pH was then adjusted to ~2 by addition of 2 M HCl solution to terminate the reaction. The reaction mixture was extracted with ethyl acetate, the organic phase was concentrated and finally purified by combiflash column chromatography to give a white solid product (0.77 g, 70% yield). The product was characterized by 1H-NMR (CDCl3): δ 1.354 (12H, s), 1.517 (3H, d, J = 7.2 Hz), 3.667 (3H, s), 3.750 (1H, m), 7.323 (2H, d, J = 7.2 Hz), 7.796 (2H, d, J = 7.2 Hz).

References

[1] Patent: WO2006/63167, 2006, A1. Location in patent: Page/Page column 23; 24

83636-46-8
73183-34-3
890839-11-9
Synthesis of methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate from 2-(4-BroMo-phenyl)-propionic acid Methyl ester and Bis(pinacolato)diboron

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Suppliers

Global Suppliers ( 19)
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Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4905 55
Shanghai ShiXian Chemical Technology Co., Ltd. 13764359345 990877971@qq.com China 1917 50
Shanghai Puhao Chemical Technology Co. Ltd. 13761817188 774028079@qq.com China 311 58
Zhengzhou Alfa Chemical Co.,Ltd +86-18530059196 sale04@alfachem.cn China 9733 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 2383948258 19172820304 2383948258@qq.com China 12983 58
Guangzhou Yunmen Biotechnology Co., Ltd 0751-18902340975/189023400307 18902340307 3356812514@qq.com China 9225 58
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Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58
Guangdong Fangxin Biotechnology Co., Ltd. 0751-2838688 13376594225 1276075424@qq.com China 9930 58
methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Benzeneacetic acid, α-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester 890839-11-9