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2-METHYL-5-NITROBENZOTRIFLUORIDE

2-METHYL-5-NITROBENZOTRIFLUORIDE structure

CAS No.: 89976-12-5

Chemical Name:: 2-METHYL-5-NITROBENZOTRIFLUORIDE

Synonyms: Ponatinib Impurity 6;4-NITRO-2-(TRIFLUOROMETHYL)TOLUENE;PotinibImpurity6;-5-nitrobenzotrifL;2-methyl-5-nitrotoluene;4-nitro-2-trifluorotoluen;4-nitro-2-trifluorotoluene;2-METHYL-5-NITROBENZOTRIFLUORIDE;Para-methyltrifluoromethylbenzene;3-TrifluoroMethyl-4-Methylnitrobenzene

CBNumber:: CB4308218

Molecular Formula:: C8H6F3NO2

Molecular Weight:: 205.13

MDL Number:: MFCD01631684

MOL File:: 89976-12-5.mol

MSDS File:: SDS

Last updated:2026-05-28 02:57:10

Product description	Number	Pack Size	Price
2-Methyl-5-nitrobenzotrifluoride	M2798	1G	$23
2-Methyl-5-nitrobenzotrifluoride	M2798	5G	$75
2-Methyl-5-nitrobenzotrifluoride ≥95%	PC0422	5g	$21
2-Methyl-5-nitrobenzotrifluoride ≥95%	PC0422	25g	$55
2-Methyl-5-nitrobenzotrifluoride ≥95%	PC0422	100g	$204
More product size

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2-METHYL-5-NITROBENZOTRIFLUORIDE Properties

Melting point	34-35 °C
Boiling point	220.5±35.0 °C(Predicted)
Density	1.357±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Solid
color	Off-white
Water Solubility	Slightly soluble in water.
Sensitive	Moisture Sensitive
InChI	InChI=1S/C8H6F3NO2/c1-5-2-3-6(12(13)14)4-7(5)8(9,10)11/h2-4H,1H3
InChIKey	SVQCVQCIZWSPPX-UHFFFAOYSA-N
SMILES	C1(C)=CC=C([N+]([O-])=O)C=C1C(F)(F)F
CAS DataBase Reference	89976-12-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Danger

Hazard statements

H302-H312-H315-H319-H332-H335

Precautionary statements

P261-P280-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

20/21/22-36/37/38

Safety Statements

23-26-36/37/39

Hazard Note

Harmful

HazardClass

IRRITANT-HARMFUL

HazardClass

6.1

HS Code

2904990090

NFPA 704

	1
2		0

2-METHYL-5-NITROBENZOTRIFLUORIDE price More Price(72)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2798	2-Methyl-5-nitrobenzotrifluoride	89976-12-5	1G	$23	2026-04-30	Buy
TCI Chemical	M2798	2-Methyl-5-nitrobenzotrifluoride	89976-12-5	5G	$75	2026-04-30	Buy
Apolloscientific	PC0422	2-Methyl-5-nitrobenzotrifluoride ≥95%	89976-12-5	5g	$21	2026-06-04	Buy
Apolloscientific	PC0422	2-Methyl-5-nitrobenzotrifluoride ≥95%	89976-12-5	25g	$55	2026-06-04	Buy
Apolloscientific	PC0422	2-Methyl-5-nitrobenzotrifluoride ≥95%	89976-12-5	100g	$204	2026-06-04	Buy

Product number	Packaging	Price	Buy
M2798	1G	$23	Buy
M2798	5G	$75	Buy
PC0422	5g	$21	Buy
PC0422	25g	$55	Buy
PC0422	100g	$204	Buy

2-METHYL-5-NITROBENZOTRIFLUORIDE Chemical Properties,Uses,Production

Chemical Properties

light yellow or crystalline

Uses

2-METHYL-5-NITROBENZOTRIFLUORIDE can be employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field.

Synthesis

13630-19-8

89976-12-5

General procedure for the synthesis of 2-methyl-5-nitrobenzotrifluoride from o-toluotrifluoride: 50 g of 2-trifluoromethyltoluene and 250 g of 98% sulfuric acid were added to a 250 mL four-necked flask with stirring and cooled to 10°C. The reaction was carried out over a period of time. 50 g of 65% nitric acid was added slowly and dropwise over a period of about 2 hours to ensure complete reaction. Upon completion of the reaction, the reaction solution was poured into 200 g of crushed ice and layered with 150 mL of dichloromethane. The aqueous phase was extracted once more with 100 mL of dichloromethane and the organic phases were combined. The organic phase was washed sequentially with 80 mL of saturated sodium bicarbonate solution and 50 mL of water. Concentration to dryness gave 62 g of a light yellow oily product in 97% yield. The product did not need further purification and could be used directly in the next reaction.

References

[1] Patent: CN106316864, 2017, A. Location in patent: Paragraph 0049; 0050; 0056; 0057; 0063; 0064

2-METHYL-5-NITROBENZOTRIFLUORIDE synthesis

Synthesis of 2-METHYL-5-NITROBENZOTRIFLUORIDE from 2-Methylbenzotrifluoride

2-METHYL-5-NITROBENZOTRIFLUORIDE Preparation Products And Raw materials

Raw materials

2-Bromo-4-nitrotoluene 2-Methylbenzotrifluoride Sodium trifluoroacetate

Preparation Products

4-Methyl-3-(trifluoromethyl)aniline

2-METHYL-5-NITROBENZOTRIFLUORIDE Suppliers

Global( 245)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Fullone Chemical Co., Ltd.	+86-13328197671 +86-13861172460	sales@borenchem.cn	China	1055	58
Jinan Zhonghan Chemical Technology Co., LTD.	+undefined15066662237	3281004549@qq.com	China	291	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Changzhou Fullone Chemical Co., Ltd.	58
Jinan Zhonghan Chemical Technology Co., LTD.	58
Capot Chemical Co.,Ltd.	60
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2-METHYL-5-NITROBENZOTRIFLUORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-30	2-METHYL-5-NITROBENZOTRIFLUORIDE 89976-12-5		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2026-02-02	2-Methyl-5-nitrobenzotrifluoride 89976-12-5		50mg	99%HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
2019-07-06	2-METHYL-5-NITROBENZOTRIFLUORIDE 89976-12-5	$1.00	1KG	99%		Career Henan Chemical Co

2-METHYL-5-NITROBENZOTRIFLUORIDE
89976-12-5
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-Methyl-5-nitrobenzotrifluoride
89976-12-5
99%HPLC
Shaanxi Dideu Medichem Co. Ltd

2-METHYL-5-NITROBENZOTRIFLUORIDE
89976-12-5
$1.00
99%
Career Henan Chemical Co

2-METHYL-5-NITROBENZOTRIFLUORIDE Spectrum

2-METHYL-5-NITROBENZOTRIFLUORIDE(89976-12-5)¹HNMR 2-METHYL-5-NITROBENZOTRIFLUORIDE(89976-12-5)FT-IR

89976-12-5(2-METHYL-5-NITROBENZOTRIFLUORIDE)Related Search:

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2-METHYL-5-NITROBENZOTRIFLUORIDE Benzene,1-Methyl-4-nitro-2-(trifluoroMethyl)- 2-Methyl-5-nitrobenzotrifluoride, 97+% 3-TrifluoroMethyl-4-Methylnitrobenzene 4-Nitro-2-(trifluoromethyl)toluene, 4-Methyl-3-(trifluoromethyl)nitrobenzene 4-nitro-2-trifluorotoluen 4-nitro-2-trifluorotoluene 2-methyl-5-nitrotoluene -5-nitrobenzotrifL PotinibImpurity6 Para-methyltrifluoromethylbenzene 4-NITRO-2-(TRIFLUOROMETHYL)TOLUENE Ponatinib Impurity 6 89976-12-5 Fluorine series