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CRUFOMATE

CAS No.
299-86-5
Chemical Name:
CRUFOMATE
Synonyms
4-t;M-1261;Rulene;MONTREL;Ruelene;Amidofos;Crufomat;dowdo132;DOWCO 132;CRUFOMATE
CBNumber:
CB4311757
Molecular Formula:
C12H19ClNO3P
Molecular Weight:
291.71
MDL Number:
MFCD00055452
MOL File:
299-86-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:29:00

CRUFOMATE Properties

Melting point 60℃
Boiling point bp0.01 117-118°
Density 1.176
refractive index nD20 1.5142
form solid
pka 0.05±0.70(Predicted)
Water Solubility 4.975g/L(temperature not stated)
Henry's Law Constant 3.9×103 mol/(m3Pa) at 25℃, HSDB (2015)
EWG's Food Scores 1
FDA UNII V82Q65924L
EPA Substance Registry System Crufomate (299-86-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H312-H410
Precautionary statements  P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P273-P391-P501
Hazard Codes  Xn,N
Risk Statements  21/22-50/53
Safety Statements  36/37-60-61
RIDADR  UN2783 (solid)
OEB B
OEL TWA: 5 mg/m3, STEL: 20 mg/m3
HS Code  29299090
Hazardous Substances Data 299-86-5(Hazardous Substances Data)
Toxicity LD50 in male, female rats (mg/kg): 635, 460 orally (Gaines)

CRUFOMATE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C825500 Crufomate 299-86-5 25mg $165 2021-12-16 Buy
Product number Packaging Price Buy
C825500 25mg $165 Buy

CRUFOMATE Chemical Properties, Uses, Production

Description

Crufomate is a white crystalline solid; thecommercial product is a yellow oil. Molecularweight=291.71; Boiling point=(decomposes); Freezing/Melting point=(decomposes) 63℃. Insoluble in water.

Chemical Properties

Crufomate is a white crystalline solid; the commercial product is a yellow oil.

Uses

Systemic insecticide and anthelmintic.

Uses

Crufomate is an organophosphate pesticide. Crufomate is an anthelmintic that functions as a potent inhibitor of an acetylcholinesterase in the anterior end of the worms. Crufomate is also used to combat bovine hypodermatosis.

Definition

ChEBI: Crufomate is an alkylbenzene.

General Description

White crystalline solid Mp: 61.5°C. The commercial product is a yellow oil. A phosphoramidate insecticide.

Reactivity Profile

CRUFOMATE is combustible; liquid formulations containing organic solvents may be flammable. Incompatible with strongly basic and strongly acidic materials. Unstable over long periods in aqueous preparations or above140°F. Emits toxic fumes of POx, Cl2 and NOx when heated to decomposition (Hazardous Chemicals Desk Reference p. 272 (1987)).

Hazard

Cholinesterase inhibitor. Questionable carcinogen.

Agricultural Uses

Insecticide, Anthelmintic (for cattle): All residue limits for crufomate, as listed in 40 CFR 180.295, were revoked by the U.S. EPA on June 9, 1993. All registered uses of crufomate in or on fat, meat, and meat byproducts of cattle, goats, and sheep were canceled It is applied as a spray on plants to kill insects, grubs, and worms on cattle. Not listed for use in EU countries

Trade name

DOWCO® 132[C]; MONTREL®[C]; RUELENE®[C]; DRENCH®[C]; RULENE®[C]

Potential Exposure

A potential danger to those involved in the manufacture, formulation, and application of this insecticide and anthelmintic for cattle.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, beginrescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24-36 h.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool wellventilated area away from heat. Also, avoid contact withoxidizers (such as peroxides, permanganates, chlorates, perchlorates, and nitrates).

Shipping

UN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Contact with oxidizers may cause the release of phosphorous oxides. Contact with strong reducing agents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Decomposes on heating, forming corrosive and toxic fumes of hydrogen chloride and nitrogen and phosphorous oxides. Incompatible with strongly alkaline and strongly acidic media. Unstable over long periods in aqueous preparations or above 60°C.

Waste Disposal

Crufomate decomposes above pH 7.0 in alkaline media. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office

CRUFOMATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 69)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 18080918076 800078821@qq.com China 9706 55
The future of Shanghai Industrial Co., Ltd. 021-61552785 sales@shshiji.com China 9531 55
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912 422131432@qq.com China 9970 55
TianJin Alta Scientific Co., Ltd. 022-65378550-8551 contact@altascientific.com China 2772 58
Alta Scientific Co., Ltd. 022-6537-8550 15522853686 sales@altasci.com.cn China 4508 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-85201366 18938635012 sales@regentsciences.com China 9382 58
RUELENE (TM) MONTREL crufomate (bsi,iso,ansi) 4-TERT-BUTYL-2-CHLOROPHENYLMETHYLMETHYLPHOSPHORAMIDE (4-tetra-Butyl-2-chlorophenylmethyl methylphosphoramidate crufomat (ISO) 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate DOWCO 132 ENT 25602-X CRUFOMATE Cruformate(content>90%) Cruformate emulsion(content>20%) 2-chloro-4-(1,1-dimethylethyl)phenylmethylmethylphosphoramidate 4-t-butyl-2-chloro-phenoesterwithmethylmethylphosphoramidate 4-t-Butyl-2-chlorophenyl methyl methylphosphoramidate 4-t-butyl-2-chlorophenylmethylmethylphosphoramidate 4-tert.butyl2-chlorophenylmethylphosphoramidatedemethyle 4-tert.butyl2-chlorophenylmethylphosphoramidatedemethyle(french) 4-tert-Butyl-2-chlorophenyl methyl methylamidophosphate 4-tert-Butyl-2-Chlorophenyl methyl methylphosphoramidate 4-tert-Butyl-2-chlorophenyl O-methyl methylphosphoroamidate 4-tert-butyl-2-chlorophenylmethylmethylphosphoramidate 4-tert-butyl-2-chlorophenyln-methylo-methylphosphoramidate Amidofos Amidophos Crufomat Crufomate A crufomatea Cruformate dowdo132 M-1261 Methylphosphoramidic acid, 4-t-butyl-2-chlorophenyl methyl ester Methylphosphoramidic acid, 4-tert-butyl-2-chlorophenyl methyl ester methyl-phosphoramidicaci4-tert-butyl-2-chlorophenylmethylester methylphosphoramidicacid,4-t-butyl-2-chlorophenylmethylester methylphosphoramidicacid2-chloro-4-(1,1-dimethylethyl)phenylmethylester methylphosphoramidicacid4-tert-butyl-2-chlorophenylmethylester N,O-Dimethyl-o-(4-tert-butyl-2-chlorophenyl)phosphoramidate O-(4-tert Butyl-2-chloor-fenyl)-O-methyl-fosforzuur-N-methyl-amide o-(4-tertbutyl-2-chloor-fenyl)-o-methyl-fosforzuur-n-methyl-amide O-(4-tert-Butyl-2-chlorophenyl) O-methyl N-methylamido phosphate o-(4-tert-butyl-2-chlorophenyl)o-methyln-methylamidophosphate o-(4-tert-Butyl-2-chlor-phenyl)-O-methyl-phosphorsaeure-N-methylamid O-(4-Terz.-butil-2-cloro-fenil)-O-metil-fosforammide O-Methyl O-2-chloro-4-tert-butylphenyl N-methylamidophosphate o-methyl-o-(4-tert-butyl-2-chlorophenyl)methylphosphoramidate ruelenedrench Rulene 4-TERT-BUTYL-2-CHLOROPHENYLMETHYL-N-METHYL-PHOSPHORAMIDATE 4-TERT-BUTYL-2-CHLOROPHENYL METHYLPHOSPHORAMIDATE 4-t (RS)-4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate [(4-tert-butyl-2-chloro-phenoxy)-methoxy-phosphoryl]-methyl-amine N-[(4-tert-butyl-2-chloro-phenoxy)-methoxy-phosphoryl]methanamine N-[(4-tert-butyl-2-chlorophenoxy)-methoxyphosphoryl]methanamine Ruelene (TM) 50mg [299-86-5] 4-tert-Butyl-2-chlorophenyl Methyl N- NSC 253463 o-methylo-2-chloro-4-tert-butylphenyln-methylamidophosphate