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ChemicalBook >> CAS DataBase List >>2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] Structure
2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] structure
CAS No.
1268273-90-0
Chemical Name:
2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]
Synonyms
HSP70-IN-1;HSP70-IN-27c;HSP70 inhibitor 1;HSP70-IN-1( LUN-00465);HSP70-IN-1, 10 mM in DMSO;HSP70 IN 1,inhibit,HSP-70-IN-1,Heat shock proteins,Inhibitor,HSP70IN1,HSP;2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl];Acetamide, 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]-;N-(3-{[4-(Benzyloxy)-2-(4-methyl-1-piperazinyl)-5-pyrimidinyl]sulfanyl}phenyl)glycinamide hydrochloride
CBNumber:
CB43166002
Molecular Formula:
C24H28N6O2S
Molecular Weight:
464.58
MDL Number:
MOL File:
1268273-90-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:23:38
Request For Quotation

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (107.62 mM)
form Solid
pka 13.27±0.70(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth TAC27390 HSP70-IN-1 1268273-90-0 5mg $756.5 2026-06-05 Buy
Biosynth TAC27390 HSP70-IN-1 1268273-90-0 10mg $1210.4 2026-06-05 Buy
Biosynth TAC27390 HSP70-IN-1 1268273-90-0 25mg $1973.25 2026-06-05 Buy
Biosynth TAC27390 HSP70-IN-1 1268273-90-0 50mg $3157.5 2026-06-05 Buy
ChemScene CS-6368 HSP70-IN-1 98.07% 1268273-90-0 5mg $314 2026-06-04 Buy
Product number Packaging Price Buy
TAC27390 5mg $756.5 Buy
TAC27390 10mg $1210.4 Buy
TAC27390 25mg $1973.25 Buy
TAC27390 50mg $3157.5 Buy
CS-6368 5mg $314 Buy

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] Chemical Properties, Uses, Production

Uses

HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM.

IC 50

HSP70; Caspase-3/7: 1.9 μM (IC50, MOLM13 cells)

References

[1] Taldone T, et al. Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70. J Med Chem. 2014 Feb 27;57(4):1208-24. DOI:10.1021/jm401552y

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] Suppliers

Global Suppliers ( 44)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 7983 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9777 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Twochem Co.Ltd. 021-58111628 15800915896 sales@twochem.com China 1782 58
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3307 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 18081075745 chemflowtech@sina.com China 1883 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
Supplier Advantage
BOC Sciences 65
Shanghai Haozhixiang Biotechnology Co., Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
Shanghai SuperLan Chemcial Technique Centre 58
Twochem Co.Ltd. 58
Angel Pharmatech, Ltd. 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 58
InvivoChem 58

View Latest Price from 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] pictures 2019-12-24 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]
1268273-90-0
 $1.00 1g 99% 20kg Career Henan Chemical Co
2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] pictures 2019-12-24 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]
1268273-90-0
 $1.00 1g 99% 20kg Career Henan Chemical Co

1268273-90-0 (2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]) Related Search:

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HSP70-IN-1 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] N-(3-{[4-(Benzyloxy)-2-(4-methyl-1-piperazinyl)-5-pyrimidinyl]sulfanyl}phenyl)glycinamide hydrochloride HSP70-IN-27c HSP70 inhibitor 1 Acetamide, 2-amino-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl]- HSP70-IN-1( LUN-00465) HSP70 IN 1,inhibit,HSP-70-IN-1,Heat shock proteins,Inhibitor,HSP70IN1,HSP HSP70-IN-1, 10 mM in DMSO 1268273-90-0 API