4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE
- CAS No.
- 214360-58-4
- Chemical Name:
- 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE
- Synonyms
- 4-FLUOROPHENYLB;SWZn-214360-58-4;4-fluorophenylborate pinacol ester;4-FLUOROPHENYLBORONIC ACID, PINACOL ESTER;4-Fluorobenzeneboronic acid, pinacol ester;4-Fluorobenzeneboronic acid, pinacol ester 97%;2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1,3,2-Dioxaborolane,2-(4-fluorophenyl)-4,4,5,5-tetraMethyl-;4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE;1-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
- CBNumber:
- CB4321462
- Molecular Formula:
- C12H16BFO2
- Molecular Weight:
- 222.06
- MDL Number:
- MFCD03453665
- MOL File:
- 214360-58-4.mol
| Boiling point | 279.4±23.0 °C(Predicted) |
|---|---|
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to lump to clear liquid |
| color | White or Colorless to Light yellow to Light orange |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BML00003 | 4-Fluorophenylboronic acid, pinacol ester Aldrich | 214360-58-4 | 1g | $36.7 | 2025-07-31 | Buy |
| TCI Chemical | F1201 | 2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 214360-58-4 | 5G | $41 | 2025-07-31 | Buy |
| TCI Chemical | F1201 | 2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 214360-58-4 | 25G | $122 | 2025-07-31 | Buy |
| TRC | F621178 | 4-Fluorophenylboronic acid, pinacol ester | 214360-58-4 | 1g | $75 | 2021-12-16 | Buy |
| AK Scientific | AMTB673 | 4-Fluorophenylboronic acid, pinacol ester | 214360-58-4 | 10g | $75 | 2021-12-16 | Buy |
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE Chemical Properties,Uses,Production
Synthesis
73183-34-3
460-00-4
214360-58-4
General steps: 1. Stirring reaction: potassium acetate (KOAc, 0.073 g, 0.09 mmol) and 1,1'-bis(diphenylphosphino)ferrocene-palladium(II) dichloride-dichloromethane complex (PdCl2(dppf)-CH2Cl2, 0.613 g, 3.5 mmol) were added under argon protection to a mixture of potassium acetate (1b, R = F 0.613 g, 3.5 mmol) and bis(pinacolato)diboron (2, 1.161 g, 4.5 mmol) in a solution of dimethyl sulfoxide (DMSO, 1.601 g). The reaction mixture was stirred at 80°C for 1.5 hours. 2. Extraction: Upon completion of the reaction, the reaction solution was cooled to room temperature, the reaction was quenched by the addition of ice water, followed by extraction of the organic layer with ethyl acetate (EtOAc, 80 mL × 2). 3. Drying and concentration: The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to obtain the crude product. 4. Purification: The crude product was purified by column chromatography (silica gel, eluent: hexane/EtOAc = 9:1) to afford 4-fluorophenylboronic acid pinacol ester (3b, R = F) in 93% yield.
References
[1] Patent: JP5966165, 2016, B2. Location in patent: Paragraph 0056-0062
[2] Journal of the American Chemical Society, 2016, vol. 138, # 9, p. 2985 - 2988
[3] Advanced Synthesis and Catalysis, 2016, vol. 358, # 6, p. 977 - 983
[4] Journal of Fluorine Chemistry, 2015, vol. 178, p. 195 - 201
[5] ACS Catalysis, 2018, vol. 8, # 5, p. 4049 - 4054
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
View Lastest Price from 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE
214360-58-4
|
US $1.00 / KG | 1KG | 97%-99% | 1kg;5kg;100kg | Career Henan Chemical Co |
-
- 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE
214360-58-4
- US $1.00 / KG
- 97%-99%
- Career Henan Chemical Co
214360-58-4(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)FLUOROBENZENE)Related Search:
1of4
