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H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

CAS No.
229961-08-4
Chemical Name:
H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
Synonyms
APELIN 12;RPRLSHKGPMPF;Apelin 12 - 1 mg;Apelin-12,(Des-Gln1)-Apelin-13;APELIN-12 (HUMAN, BOVINE, MOUSE, RAT);ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE;PREPROAPELIN (66-77) (HUMAN, BOVINE, MOUSE, RAT);(DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT);H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
CBNumber:
CB4333520
Molecular Formula:
C64H103N21O14S
Molecular Weight:
1422.7
MDL Number:
MFCD05664679
MOL File:
229961-08-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:44

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Properties

RTECS CD7310000
storage temp. -15°C
form Lyophilized powder
color White to off-white
Sequence H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
InChIKey KIODTAJAFBDDGP-TZIGXLGFSA-N

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 301879 Apelin-12 Purified 50ul $1190 2026-06-03 Buy
Biosynth FA109622 Apelin-12 (human, bovine, mouse, rat) 229961-08-4 5mg $900 2026-06-04 Buy
Biosynth FA109622 Apelin-12 (human, bovine, mouse, rat) 229961-08-4 2mg $900 2026-06-04 Buy
Biosynth FA109622 Apelin-12 (human, bovine, mouse, rat) 229961-08-4 1mg $900 2026-06-04 Buy
Biosynth FA109622 Apelin-12 (human, bovine, mouse, rat) 229961-08-4 10mg $1210.9 2026-06-04 Buy
Product number Packaging Price Buy
301879 50ul $1190 Buy
FA109622 5mg $900 Buy
FA109622 2mg $900 Buy
FA109622 1mg $900 Buy
FA109622 10mg $1210.9 Buy

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Chemical Properties, Uses, Production

Uses

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].

IC 50

HIV-1

References

[1] Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203. DOI:10.4103/0976-500X.114600
[2] Pisarenko OI, et al. Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Mol Cell Biochem. 2014;391(1-2):241-250. DOI:10.1007/s11010-014-2008-4
[3] Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. DOI:10.26355/eurrev_201806_15273
[4] Ohno S, et al. Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs. Regul Pept. 2012;174(1-3):71-78. DOI:10.1016/j.regpep.2011.12.002

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Suppliers

Global Suppliers ( 97)
Supplier Tel Email Country ProdList Advantage
Nanjing TGpeptide Biotechnology Co.,Ltd. 18115476705 sales@tgpeptide.com China 3058 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1010 55
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55

View Latest Price from H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH pictures 2026-07-01 H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH pictures 2020-02-17 H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
$7.00 1KG 99% 100KG Career Henan Chemical Co
 H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH pictures 2020-02-17 H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
$7.00 1KG 99% 100KG Career Henan Chemical Co
(Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat) Apelin-12,(Des-Gln1)-Apelin-13 Apelin-12 (human, bovine, mouse, rat) H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Apelin-12 (huMan, bovine, Mouse, rat) (Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat) (DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT) APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT) APELIN 12 APELIN-12 (HUMAN, BOVINE, MOUSE, RAT) ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE PREPROAPELIN (66-77) (HUMAN, BOVINE, MOUSE, RAT) RPRLSHKGPMPF L-Phenylalanine, L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl- Apelin-12 (human, bovine, mouse, rat)?/(Des-Gln1)-Apelin-13 (human, bovine, mouse, rat), Preproapelin (66-77) (human, bovine, mouse, rat), Apelin Precursor (66-77) (human, bovine, mouse, rat) Apelin 12 - 1 mg H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH 229961-08-4 C64H103N21O14S Apelin receptor peptide Elisa Kit-Mouse Elisa Kit