H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- CAS No.
- 229961-08-4
- Chemical Name:
- H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- Synonyms
- APELIN 12;RPRLSHKGPMPF;Apelin 12 - 1 mg;Apelin-12,(Des-Gln1)-Apelin-13;APELIN-12 (HUMAN, BOVINE, MOUSE, RAT);ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE;PREPROAPELIN (66-77) (HUMAN, BOVINE, MOUSE, RAT);(DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT);H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- CBNumber:
- CB4333520
- Molecular Formula:
- C64H103N21O14S
- Molecular Weight:
- 1422.7
- MDL Number:
- MFCD05664679
- MOL File:
- 229961-08-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 301879 | Apelin-12 Purified | 50ul | $1190 | 2026-06-03 | Buy | |
| Biosynth | FA109622 | Apelin-12 (human, bovine, mouse, rat) | 229961-08-4 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA109622 | Apelin-12 (human, bovine, mouse, rat) | 229961-08-4 | 2mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA109622 | Apelin-12 (human, bovine, mouse, rat) | 229961-08-4 | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA109622 | Apelin-12 (human, bovine, mouse, rat) | 229961-08-4 | 10mg | $1210.9 | 2026-06-04 | Buy |
H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Chemical Properties, Uses, Production
Uses
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].
IC 50
HIV-1
References
[1] Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203. DOI:10.4103/0976-500X.114600
[2] Pisarenko OI, et al. Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Mol Cell Biochem. 2014;391(1-2):241-250. DOI:10.1007/s11010-014-2008-4
[3] Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. DOI:10.26355/eurrev_201806_15273
[4] Ohno S, et al. Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs. Regul Pept. 2012;174(1-3):71-78. DOI:10.1016/j.regpep.2011.12.002
H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing TGpeptide Biotechnology Co.,Ltd. | 18115476705 | sales@tgpeptide.com | China | 3058 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1010 | 55 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
View Latest Price from H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-01 | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
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2020-02-17 | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co | |
![]() |
2020-02-17 | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-

- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
- $7.00
- 99%
- Career Henan Chemical Co
-

- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
229961-08-4
- $7.00
- 99%
- Career Henan Chemical Co




