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BEAUVERICIN

BEAUVERICIN structure

CAS No.: 26048-05-5

Chemical Name:: BEAUVERICIN

Synonyms: nivea;Beauveria bassiana (Balsamo) Vuillemin;bovein;bassiana;beauverin;Beauveria;BEAUVERICIN;BEAUVERFICIN;Beauveria sp.;Beauvericin 97%

CBNumber:: CB4345714

Molecular Formula:: C45H57N3O9

Molecular Weight:: 783.95

MDL Number:: MFCD30541349

MOL File:: 26048-05-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

Product description	Number	Pack Size	Price
Beauvericin ≥97% (HPLC)	B7510	5mg	$248
Beauvericin VETRANAL?, analytical standard	37012	100μg	$895
Beauvericin ≥95%	11426	1mg	$39
Beauvericin ≥95%	11426	5mg	$164
Beauvericin ≥95%	11426	10mg	$308
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BEAUVERICIN Properties

Melting point	93-94℃
Boiling point	975.6±65.0 °C(Predicted)
Density	1.126±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMSO (30 mg/ml)
pka	-1.02±0.70(Predicted)
form	Solid
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey	GYSCAQFHASJXRS-ABKJGVMTSA-N
SMILES	C(C1C=CC=CC=1)C1C(OC(C(N(C(C(OC(C(C)C)C(=O)N(C)C(CC2C=CC=CC=2)C(=O)OC(C(C)C)C(=O)N1C)=O)CC1C=CC=CC=1)C)=O)C(C)C)=O
EWG's Food Scores	1
FDA UNII	26S048LS2R

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H315-H302+H312+H332
Precautionary statements	P280-P261-P271
WGK Germany	3
HS Code	29419090

BEAUVERICIN price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B7510	Beauvericin ≥97% (HPLC)	26048-05-5	5mg	$248	2026-04-30	Buy
Sigma-Aldrich	37012	Beauvericin VETRANAL?, analytical standard	26048-05-5	100μg	$895	2022-05-15	Buy
Cayman Chemical	11426	Beauvericin ≥95%	26048-05-5	1mg	$39	2026-04-30	Buy
Cayman Chemical	11426	Beauvericin ≥95%	26048-05-5	5mg	$164	2026-04-30	Buy
Cayman Chemical	11426	Beauvericin ≥95%	26048-05-5	10mg	$308	2026-04-30	Buy

Product number	Packaging	Price	Buy
B7510	5mg	$248	Buy
37012	100μg	$895	Buy
11426	1mg	$39	Buy
11426	5mg	$164	Buy
11426	10mg	$308	Buy

BEAUVERICIN Chemical Properties,Uses,Production

Description

Beauvericin (CAS 26048-05-5) induces apoptosis in A549 cancer cells.1 Disrupts mitochondrial volume regulation.2 Antifungal activity acting via inhibition of both multidrug efflux and TORC1 kinase.3 Crosses the blood-brain barrier in mice.4 Inhibits HIV-1 integrase.5

Chemical Properties

White powder

Uses

Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities. At the molecular level, beauvericin exhibits ionophoric properties, and inhibits acyl-CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels.

Uses

Toxic depsipeptide with antibiotic and insecticidal effects.Beauvericin is a toxic depsipeptide with antibiotic and insecticidal effects.

Definition

ChEBI: A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues.

in vivo

Beauvericin (5 mg/kg; i.p.; after the first dosing cycle, observe for two days and continue the second dosing cycle) reduces tumor volume and increases necrosis in allogeneic transplant model mice^[3]. Beauvericin (3, 5, 7 mg/kg; i.p.; once a week for three weeks) can significantly inhibit the growth of H22 allogeneic transplant model mice and increase the levels of TNF-α and IL-2 in mice^[5].

Animal Model:	BALB/c mice injected subcutaneously with mouse CT-26 colon cancer cells on the right side^[3]
Dosage:	5 mg/kg
Administration:	ntraperitoneal injection (i.p.)；The drug was administered on the third day after the injection of colon cancer cells and continued once a day for five days, then stopped for two days of observation, and continued on the tenth day after the injection of colon cancer cells, and continued once a day for four days.
Result:	Reduced the average tumor volume by 52.8 % and the average tumor weight by 60 %.

Animal Model:	Human cervical cancer KB-3-1 xenograft mouse model^[3]
Dosage:	5 mg/kg
Administration:	Intraperitoneal injection (i.p.)； The drug was administered once a day starting on the fifth day after cervical cancer injection for five days, followed by two days of observation. The drug was administered once a day starting on the twelfth day after cervical cancer cell injection for four days.
Result:	Reduced the average tumor volume by 31.3 % and the average tumor weight by 31.2 %.

IC 50

ACAT

References

[1] CHIEN-LIN LU. Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells.[J]. Journal of Toxicological Sciences, 2016, 41 3: 429-437. DOI:10.2131/jts.41.429
[2] ANTON A. TONSHIN . The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis[J]. Toxicology, 2010, 276 1: Pages 49-57. DOI:10.1016/j.tox.2010.07.001
[3] TANVI SHEKHAR-GUTURJA. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling[J]. Nature chemical biology, 2016, 12 10: 867-875. DOI:10.1038/nchembio.2165
[4] LIEN TAEVERNIER . Blood-brain barrier transport kinetics of the cyclic depsipeptide mycotoxins beauvericin and enniatins[J]. Toxicology letters, 2016, 258: Pages 175-184. DOI:10.1016/j.toxlet.2016.06.1741
[5] CHA-GYUN SHIN. Beauvericin and enniatins H, I and MK1688 are new potent inhibitors of human immunodeficiency virus type-1 integrase[J]. Journal of Antibiotics, 2009, 62 12: 687-690. DOI:10.1038/ja.2009.102

BEAUVERICIN Preparation Products And Raw materials

Raw materials

Filler Potassium Phosphate Monobasic

Preparation Products

BEAUVERICIN Suppliers

Global( 218)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Zhuanglai Chemical Trading Co.,Ltd	13343047651	admin@zlchemi.com	China	3689	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7239	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +86-18080483897	sales@biopurify.com	China	4616	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5898	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	+8618062405514	ada@ipurechemical.com	China	10224	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2777	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58

Supplier	Advantage
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Chengdu Biopurify Phytochemicals Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	58
Longyan Tianhua Biological Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from BEAUVERICIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-27	Beauvericin 26048-05-5	$64.00		≥98%	10g	TargetMol Chemicals Inc.
2026-07-27	Beauvericin 26048-05-5	$64.00		≥98%	10g	TargetMol Chemicals Inc.
2025-05-23	BEAUVERICIN 26048-05-5	$50.00	1kg	99	5000	Hebei Zhuanglai Chemical Trading Co Ltd

Beauvericin
26048-05-5
$64.00
≥98%
TargetMol Chemicals Inc.

Beauvericin
26048-05-5
$64.00
≥98%
TargetMol Chemicals Inc.

BEAUVERICIN
26048-05-5
$50.00
99
Hebei Zhuanglai Chemical Trading Co Ltd

BEAUVERICIN Spectrum

BEAUVERICIN(26048-05-5)¹HNMR

26048-05-5(BEAUVERICIN)Related Search:

Emamectin Bis(2-dimethylaminoethyl) ether 2-((2-(2-(DIMETHYLAMINO)ETHOXY)ETHYL) METHYLAMINO)ETHANOL, 97 1,5-DIAMINO-3-OXAPENTANE GLYCINE N-PROPYL ESTER HYDROCHLORIDE

N,N-Dimethylglycine ethyl ester Propanamide, 2-hydroxy-N,N-dimethyl- (9CI) N-(2-HYDROXYETHYL)LACTAMIDE N,N-DIMETHYL-L-PHENYLALANINE BEAUVERICIN

1,5-BIS(METHYLAMINO)-3-OXAPENTANE, 98 AC-PHE-OET N,N-DIMETHYL-2-METHOXYACETAMIDE AC-PHE-OME ethyl 2-(propylamino)acetate

beauvericin synthetase ethyl 2-(butylamino)acetate N,N-DI(2-METHOXY)ETHYLAMMONIUM ACETATE

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Beauvericin, froM Beauveria bassiana CYCLO-[D-ALPHA-HYDROXYISOVALERYL-L-N-METHYLPHENYLALANYL]3 CYCLO(-D-ALPHA-HYDROXYISOVALERYL-N-ME-PHE)3 BEAUVERICIN cyclo(d-α-hydroxyisovaleryl-l-n-methyl-phe)3 BEAUVERFICIN beauverin beauverin bassiaua vuillemin bovein Beauvericin 97% Cyclo[(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl-(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl-(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl] Cyclo(-D-a-hydroxyisovaleryl-N-Me-Phe)3 Beauvericin, 99%, from Beauveria bassiana N-Methylcyclo(L-Phe-D-Hmb-N-methyl-L-Phe-D-Hmb-N-methyl-L-Phe-D-Hmb-) Beauveria Beauveria Vuillemin Beauveria Vuillemin sp bassiana Beauveria sp. Beauveria bassiana (Bals.-Criv.) Vuill. Beauveria bassiana AS 3.4271 Beauveria brongiartii BEAUVERICIN USP/EP/BP 13C45-Beauvericin (3S,6R,9S,12R,15S,18R)-3,9,15-Tribenzyl-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexaone (3S,6R,9S,12R,15S,18R)-3,9,15-tribenzyl-4,10,16-trimethyl-6,12,18-tris(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone Beauvericin in dried down Beauvericin 100 μg/ml Acetonitrile Beauvericin in Acetonitrile Beauvericin, 10 mM in DMSO Beauveria bassiana (Balsamo) Vuillemin nivea 26048-05-5 63428-80-0 C45H57N3O9 C44H57N3O8 Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptides Other Peptides Antibiotic Intermediates & Fine Chemicals Peptides Pharmaceuticals peptide