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MILBEMECTIN A3

MILBEMECTIN A3 Structure
MILBEMECTIN A3 structure
CAS No.
51596-10-2
Chemical Name:
MILBEMECTIN A3
Synonyms
milbemycin;milbemycin A3;Milbemycin α1;milbemycinb-2;MILBEMECTIN A3;milbemectine a3;Antibiotic B-41A3;Milbemycin oxime A3;Milbemycin EP Imp B;Milbemite Impurity 1
CBNumber:
CB4359654
Molecular Formula:
C31H44O7
Molecular Weight:
528.69
MDL Number:
MFCD04972569
MOL File:
51596-10-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
Product description Number Pack Size Price
Milbemycin A3 ≥85% 18360 1mg $359
Milbemycin A3 ≥85% 18360 5mg $1075
Milbemycin A3 ≥95%byHPLC M3896-80 1mg $704
Milbemectin A3 FM157340 1mg $825
Milbemectin A3 FM157340 2mg $1375
Request For Quotation

MILBEMECTIN A3 Properties

Melting point 212-215°; mp 192-194°
alpha D20 +106° (c = 0.25 in acetone) (Aoki); D20 +106° (acetone) (Hirama)
Boiling point 725.5±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A solid
pka 12.46±0.70(Predicted)
color White to light yellow
Henry's Law Constant 6.5×102 mol/(m3Pa) at 25℃, Maniere et al. (2011)
InChIKey ZLBGSRMUSVULIE-HIKHPYAJNA-N
FDA UNII C76Y8Z9GEX
EPA Substance Registry System Milbemycin A3 (51596-10-2)

SAFETY

Risk and Safety Statements

RIDADR  2588
HazardClass  6.1(b)
PackingGroup  III

MILBEMECTIN A3 price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18360 Milbemycin A3 ≥85% 51596-10-2 1mg $359 2026-04-30 Buy
Cayman Chemical 18360 Milbemycin A3 ≥85% 51596-10-2 5mg $1075 2026-04-30 Buy
Usbiological M3896-80 Milbemycin A3 ≥95%byHPLC 51596-10-2 1mg $704 2026-06-03 Buy
Biosynth FM157340 Milbemectin A3 51596-10-2 1mg $825 2026-06-04 Buy
Biosynth FM157340 Milbemectin A3 51596-10-2 2mg $1375 2026-06-04 Buy
Product number Packaging Price Buy
18360 1mg $359 Buy
18360 5mg $1075 Buy
M3896-80 1mg $704 Buy
FM157340 1mg $825 Buy
FM157340 2mg $1375 Buy

MILBEMECTIN A3 Chemical Properties,Uses,Production

Description

Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 against adult spider mites, spider mite eggs, and C. elegans are reported at IC50 values of 5.3, 41.1, and 9.5 μg/ml.

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is a major member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

Uses

Milbemycin A3 is widely used as a pesticides in agriculture. Milbemycin A3 (Milbemycin EP Impurity B) is an antibiotic with acaricidal activity.

Definition

ChEBI: Milbemycin A3 is a milbemycin.

Synthesis

Milbemectin A3 is obtained by extracting it from the fermentation of the soil microorganism streptomyces (streptomyces hygroscopicus subsp. aureolacrimosus).

References

[1] LING-YU YANG . New nemadectin congeners with acaricidal and nematocidal activity from Streptomyces microflavus neau3 Y-3[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23 20: Pages 5710-5713. DOI: 10.1016/j.bmcl.2013.08.002

MILBEMECTIN A3 Preparation Products And Raw materials

Raw materials

Preparation Products

MILBEMECTIN A3 Suppliers

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals 		+86-17320513646 +86-17320513646 anna@molcoo.com China 9998 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14320 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8615821988213 info@longyupharma.com China 2411 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Alfa Chemistry 		+1-5166625404; Info@alfa-chemistry.com United States 20000 58
Aladdin Scientific 		tp@aladdinsci.com United States 52906 58
Shanghai Scibiotron Pharmaceutical Co., Ltd 		+86-16621589600 contact@scibiotron.com China 5783 58
QUALITY CONTROL SOLUTIONS LTD. 		+86-0755-66853366 +8613670046396 export03@qcsrm.com China 24318 58
Supplier Advantage
Moxin Chemicals 		58
Standardpharm Co. Ltd. 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
Alfa Chemistry 		58
Aladdin Scientific 		58
Shanghai Scibiotron Pharmaceutical Co., Ltd 		58
QUALITY CONTROL SOLUTIONS LTD. 		58

View Lastest Price from MILBEMECTIN A3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Milbemycin A3 pictures 2026-07-14 Milbemycin A3
51596-10-2
 $168.00-419.00 10g TargetMol Chemicals Inc.
Milbemycin Oxime EP Impurity B pictures 2025-12-16 Milbemycin Oxime EP Impurity B
51596-10-2
 10mg 98 10000000 Moxin Chemicals

51596-10-2(MILBEMECTIN A3)Related Search:

MilbeMycin A3 OxiMe MilbeMycin A4 OxiMe MILBEMECTIN A4 Miconazole IMpurity B MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE)
2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid 1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile Milbemycin oxime Isoconazole Milbemycin EP Impurity D
Milrinone Impurity 13 Miconazole Impurity Miconazole IMpurity I 5-Decyano 5-(Ethyl Formate) Milrinone Milrinone Impurity 17
Milrinone Impurity 14 Milbemycin EP Impurity E Miconazole EP Impurity E

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milbemectine a3 MILBEMECTIN A3 milbemycinb-2 (25R)-25-Methyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B Milbemycin oxime A3 (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B Antibiotic B-41A3 Milbemycin α1 (+)-Chloropseudoephedrine (hydrochloride) B 41A3, MilbeMycin alpha1, MilbeMectin Milbemycin EP Impurity B Milbemycin Impurity 2(Milbemycin EP Impurity B) Milbemycin EP Imp B Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-, (6R,25R)- Milbemite Impurity 1 Milbemycin Oxime EP Impurity B Milbemectin A3 10.0 μg/ml Acetonitrile Milbemectin A3 10 μg/mL in Acetonitrile (2R,2a'E,2a1'S,4'E,5S,6R,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-5,6,6',8',19'-pentamethyl-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one Milbemycin Oxime Impurity 2 (Milbemycin Oxime EP Impurity B) milbemycin milbemycin A3 51596-10-2 51596-20-2 C31H44O7