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MILBEMECTIN A4

MILBEMECTIN A4 structure

CAS No.: 51596-11-3

Chemical Name:: MILBEMECTIN A4

Synonyms: milbemycin A4;Milbemycin EP Impurity A;Milbemycin α3;milbemycinb-1;MILBEMECTIN A4;milbemectine a4;Antibiotic B-41A4;Milbemycin oxime A4;Milbemycin EP Imp A;B 41A4, MilbeMycin alpha3

CBNumber:: CB7359655

Molecular Formula:: C32H46O7

Molecular Weight:: 542.7

MDL Number:: MFCD04972570

MOL File:: 51596-11-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:36:23

Product description	Number	Pack Size	Price
Milbemycin A4 ≥85%	17155	1mg	$457
Milbemycin A4 ≥85%	17155	5mg	$1028
Milbemycin A4 (Antibiotic B 41A4, Milbemycin alpha3) >95%byHPLC	M3896-80A	1mg	$695
Milbemectin A4	FM157342	1mg	$825
Milbemectin A4	FM157342	2mg	$1375

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MILBEMECTIN A4 Properties

Melting point	212-215°
alpha	D20 +106° (c = 0.25 in acetone)
Boiling point	732.9±60.0 °C(Predicted)
Density	1.20±0.1 g/cm3(Predicted)
storage temp.	0-6°C
solubility	DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form	A solid
pka	12.46±0.70(Predicted)
color	White to off-white
Henry's Law Constant	7.7×10⁶ mol/(m³Pa) at 25℃, Ebert et al. (2023)
InChIKey	VOZIAWLUULBIPN-PNCZYSMLNA-N
FDA UNII	9BSH89E55Y
EPA Substance Registry System	Milbemycin A4 (51596-11-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H350
Precautionary statements	P201-P202-P280-P308+P313-P405-P501
RIDADR	2588
HazardClass	6.1(b)
PackingGroup	III

MILBEMECTIN A4 price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	17155	Milbemycin A4 ≥85%	51596-11-3	1mg	$457	2026-04-30	Buy
Cayman Chemical	17155	Milbemycin A4 ≥85%	51596-11-3	5mg	$1028	2026-04-30	Buy
Usbiological	M3896-80A	Milbemycin A4 (Antibiotic B 41A4, Milbemycin alpha3) >95%byHPLC	51596-11-3	1mg	$695	2026-06-03	Buy
Biosynth	FM157342	Milbemectin A4	51596-11-3	1mg	$825	2026-06-04	Buy
Biosynth	FM157342	Milbemectin A4	51596-11-3	2mg	$1375	2026-06-04	Buy

Product number	Packaging	Price	Buy
17155	1mg	$457	Buy
17155	5mg	$1028	Buy
M3896-80A	1mg	$695	Buy
FM157342	1mg	$825	Buy
FM157342	2mg	$1375	Buy

MILBEMECTIN A4 Chemical Properties,Uses,Production

Description

Milbemycin A₄ is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin ₄ is used as a nematocide and insecticide.

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

Uses

Acaricide.

Uses

Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3).

Definition

ChEBI: Milbemycin A4 is a milbemycin.

IC 50

Macrolide

MILBEMECTIN A4 synthesis

Synthesis of MILBEMECTIN A4 from Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (2S,6R,25R)- (9CI)

MILBEMECTIN A4 Preparation Products And Raw materials

Raw materials

Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (2S,6R,25R)- (9CI) Milbemycin K

Preparation Products

MILBEMECTIN A4 Suppliers

Global( 81)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14320	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2411	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20000	58
Wuhan Topule Biopharmaceutical Co., Ltd	+86-18327326525	masar@topule.com	China	8433	58
Aladdin Scientific		tp@aladdinsci.com	United States	52906	58
Moxin Chemicals	+86-17320513646 +86-17320513646	anna@molcoo.com	China	9998	58
Shanghai Scibiotron Pharmaceutical Co., Ltd	+86-16621589600	contact@scibiotron.com	China	5783	58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.	+86-18603013401	jack.lin@sincopharmachem.com	China	9999	58
QUALITY CONTROL SOLUTIONS LTD.	+86-0755-66853366 +8613670046396	export03@qcsrm.com	China	24318	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
Shanghai Longyu Biotechnology Co., Ltd.	58
BOC Sciences	58
Alfa Chemistry	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
Moxin Chemicals	58
Shanghai Scibiotron Pharmaceutical Co., Ltd	58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.	58
QUALITY CONTROL SOLUTIONS LTD.	58

51596-11-3(MILBEMECTIN A4)Related Search:

MilbeMycin A3 OxiMe MilbeMycin A4 OxiMe Miconazole IMpurity I Miconazole IMpurity B MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE)

2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid 1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile Milbemycin oxime Isoconazole Milbemycin EP Impurity D

Milrinone Impurity 13 Miconazole Impurity 5-Decyano 5-(Ethyl Formate) Milrinone Milrinone Impurity 17 Milrinone Impurity 14

Milbemycin EP Impurity E Miconazole EP Impurity E MILBEMECTIN A3

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milbemycinb-1 MILBEMECTIN A4 milbemectine a4 (25R)-25-Ethyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B Antibiotic B-41A4 Milbemycin α3 VOZIAWLUULBIPN-WMKNSKLVSA-N Milbemycin EP Impurity A Milbemycin Impurity 1(Milbemycin EP Impurity A) B 41A4, MilbeMycin alpha3 Milbemycin oxime A4 Milbemycin EP Imp A Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (6R,25R)- (1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21R,24S)-6'-ethyl-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one Milbemycin Oxime Impurity 1(Milbemycin Oxime EP Impurity A) Milbemectin A4 10 μg/mL in Acetonitrile (2R,2a'E,2a1'S,4'E,5S,6R,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-6-ethyl-2a1',20'-dihydroxy-5,6',8',19'-tetramethyl-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one milbemycin A4 51596-11-3 C32H46O7