Biurea
- CAS No.
- 110-21-4
- Chemical Name:
- Biurea
- Synonyms
- Hydrazodicarbonamide;1,2-hydrazinedicarboxamide;DIUREA;Biurea;p-urazine;Biurea,99%;Ureidourea;dicarbamide;Bicarbamamide;Urea, ureido-
- CBNumber:
- CB4365907
- Molecular Formula:
- C2H6N4O2
- Molecular Weight:
- 118.09
- MDL Number:
- MFCD00025398
- MOL File:
- 110-21-4.mol
- MSDS File:
- SDS
| Melting point | 247-250 °C |
|---|---|
| Boiling point | 220.6°C (rough estimate) |
| Density | 1.6040 |
| refractive index | 1.4462 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Sulfuric Acid (Sparingly, Heated) |
| pka | 10.06±0.43(Predicted) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 110-21-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | POJ4UOY01H |
| EPA Substance Registry System | Biurea (110-21-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29280000 | |||||||||
| Hazardous Substances Data | 110-21-4(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 oral in rat: > 2gm/kg | |||||||||
| NFPA 704 |
|
Biurea price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S371467 | BIUREA AldrichCPR | 110-21-4 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | S371467 | BIUREA Aldrich | 110-21-4 | 250mg | $179 | 2024-03-01 | Buy |
| TCI Chemical | B0512 | Biurea | 110-21-4 | 5g | $186 | 2026-04-30 | Buy |
| TCI Chemical | B0512 | Biurea | 110-21-4 | 25g | $474 | 2026-04-30 | Buy |
| TRC | TRC-H054710-5G | Hydrazine-1,2-dicarboxamide | 110-21-4 | 5g | $359 | 2026-06-03 | Buy |
Biurea Chemical Properties,Uses,Production
Synthesis
First, 200 mg of hydrazine sulfate was dissolved in 3 mL of 0.5 mol/L acetic acid aqueous solution. Potassium cyanate solution (275 mg of potassium cyanate dissolved in 0.93 mL of water) was slowly added dropwise to this solution. The mixture was stirred at room temperature for 4 hours. After the reaction was complete, the mixture was transferred to a 25 mL centrifuge tube. 2 mL of water was added to the centrifuge tube, and crystals formed. The precipitate was separated by centrifugation (5000 g, 5 min). The precipitate was washed twice, successively with 2 mL of anhydrous ethanol and ether, to obtain 150 mg of product. The reaction equation is as follows:

Chemical Properties
WHITE POWDER
Uses
Hydrazine-1,2-dicarboxamide is a useful compound in the process of producing protected anode active material particles for rechargeable lithium batteries.
General Description
White powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
BIUREA is chemically classified as an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard
The flash point of BIUREA is not available, however BIUREA is probably non-flammable.
Purification Methods
Crystallise the diamide from water, wash the crystals with EtOH then Et2O and dry in vacuum over P2O5. It does not decompose on drying at 110o /48hours. Its solubility in H2O is 1% at 0o. [Andrieth & Mohr Inorg Synth IV 26 1953, Beilstein 3 H 116, 3 I 56, 3 III 229.]
Biurea Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Shenyang Yuancheng Pharmaceutical Technology Co., Ltd. | 024-31298370 15040047923 | yuanchengchem@163.com | China | 252 | 52 |
| Beijing innoChem Science & Technology Co.,Ltd. | 400-810-7969 010-59572699 | ningzi.li@inno-chem.com.cn | China | 6122 | 55 |
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