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3-Methyl-7-azaindole

3-Methyl-7-azaindole Structure
3-Methyl-7-azaindole structure
CAS No.
5654-93-3
Chemical Name:
3-Methyl-7-azaindole
Synonyms
3-methyl-1H-pyrrolo[2,3-b]pyridine;7-Azaskatole;3-Methyl-7-azaindole;3-METHYL-7-AZAINDOLE(LR);3-Methylpyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-methyl-;3-Methyl-1H-pyrrolo[2,3-b]pyridine 98%;Methanone,[5-(hydroxymethyl)phenyl]phenyl-
CBNumber:
CB4382735
Molecular Formula:
C8H8N2
Molecular Weight:
132.16
MDL Number:
MFCD08272239
MOL File:
5654-93-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:47
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3-Methyl-7-azaindole Properties

Melting point 130.5-133 °C
Boiling point 352.8±15.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 8.01±0.20(Predicted)
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P301+P312+P330-P302+P352-P305+P351+P338
HS Code  2933399990

3-Methyl-7-azaindole price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS17392 3-Methyl-7-azaindole 98% 5654-93-3 1g $71 2026-06-04 Buy
Activate Scientific AS17392 3-Methyl-7-azaindole 98% 5654-93-3 5g $218 2026-06-04 Buy
Matrix Scientific 112767 3-Methyl-7-azaindole 5654-93-3 1.00g $470 2026-05-18 Buy
Synthonix M7858 3-Methyl-7-azaindole 97.0% 5654-93-3 100mg $225 2026-05-06 Buy
Synthonix M7858 3-Methyl-7-azaindole 97.0% 5654-93-3 250mg $262 2026-05-06 Buy
Product number Packaging Price Buy
AS17392 1g $71 Buy
AS17392 5g $218 Buy
112767 1.00g $470 Buy
M7858 100mg $225 Buy
M7858 250mg $262 Buy

3-Methyl-7-azaindole Chemical Properties, Uses, Production

Uses

An azaindole derivative as CRTH2 receptor antagonist.

Synthesis

2,3-Dichloropyridine

2402-77-9

Allylamine

107-11-9

3-METHYL-7-AZAINDOLE

5654-93-3

（Synthesis of (a) 3-methyl-1H-pyrrolo[2,3-b]pyridine: The intermediate was prepared by the method described by Jensen et al. (Angew. Chem. Int. Ed. 2008, 47, 888-890). Toluene (5 mL), 2,3-dichloropyridine (300 mg, 2.03 mmol), tris(dibenzylideneacetone)dipalladium (Pd2dba3, 2 mg, 0.0025 mmol), 1,1'-bis(diphenylphosphino)ferrocene (dppf, 6 mg, 0.01 mmol), sodium tert-butoxide (NaOtBu, 487 mg , 5.07 mmol) and allylamine (0.15 mL, 2.03 mmol). The reaction tube was sealed and heated at 140 °C for 20 h, followed by stirring for 24 h at room temperature. The reaction mixture was washed sequentially with water and brine, dried over anhydrous sodium sulfate (Na2SO4) and adsorbed on silica gel. Initial purification was carried out using a gradient elution of dichloromethane-hexane (0 to 60%) followed by ethyl acetate-hexane (80%) to give an orange solid product (100 mg, 37% yield).

References

[1] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890
[2] Patent: WO2010/132615, 2010, A1. Location in patent: Page/Page column 111
[3] Patent: WO2013/114332, 2013, A1. Location in patent: Page/Page column 92; 93
[4] Patent: US2014/371204, 2014, A1. Location in patent: Paragraph 0718

3-Methyl-7-azaindole Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide 2,3-Dichloropyridine Allylamine Carbamic acid, (3-ethyl-2-pyridinyl)-, 1,1-dimethylethyl ester Sodium tert-butoxide
Toluene

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Preparation Products

3-Methyl-7-azaindole Suppliers

Global Suppliers ( 93)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shanghai Feibo Chemical Technology Co., Ltd 021-58955608,2250286 15921236618 blinkzeng@gmail.com China 522 62
Dtchem Laboratories,（Gan Su）Co.,Ltd. 18993961550 18993966060 sales@techbiochem.com China 773 61
Suzhou Sibian Chemical Technology Co.,Ltd. 0512-65617459 18915409046 sales@sibian-chem.com China 1917 55
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62
Chemsky (shanghai) International Co.,Ltd 60
Shanghai Feibo Chemical Technology Co., Ltd 62
Dtchem Laboratories,（Gan Su）Co.,Ltd. 61
Suzhou Sibian Chemical Technology Co.,Ltd. 55
Shanghai T&W Pharmaceutical Co., Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55

View Latest Price from 3-Methyl-7-azaindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-METHYL-7-AZAINDOLE pictures 2020-01-03 3-METHYL-7-AZAINDOLE
5654-93-3
 $6.60 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

3-Methyl-7-azaindole Spectrum

3-METHYL-7-AZAINDOLE(5654-93-3)1HNMR

5654-93-3 (3-Methyl-7-azaindole) Related Search:

Methyl 7-azaindole-3-glyoxylate 1-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)-N,N-dimethyl-methanamine 7-Azaindole-3-carboxaldehyde L-745870 1H-Pyrrolo[2,3-b]pyridine, 3-(phenylmethyl)-
2-Propenamide, 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)- 1H-Pyrrolo[2,3-b]pyridine, 2,3-dimethyl- Ethanone, 2,2,2-trifluoro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- Boc-DL-7-azatryptophan 7-Azatryptophan monohydrate
Ethyl α-acetamido-α-carbethoxy-β-(7-aza-3-indolyl)propionate 3-([4-(4-Chlorophenyl)piperazin-1-yl]methyl)-1H-pyrrolo(2,3-b)pyridine hydrochloride Fmoc-DL-7-azatryptophan 2,2,2-Trifluoro-1-(1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-ethanone 1-(1-Ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,2,2-trifluoro-1-ethanone
2,2,2-Trifluoro-1-(1-[3-(trifluoromethyl)benzyl]-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-ethanone 6,7,8,9-Tetrahydro-5H-pyrido[2,3-b]indole Ethyl 2-(1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-oxoacetate

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3-Methylpyrrolo[2,3-b]pyridine 7-Azaskatole 1H-Pyrrolo[2,3-b]pyridine, 3-methyl- 3-Methyl-1H-pyrrolo[2,3-b]pyridine 98% 3-METHYL-7-AZAINDOLE(LR) Methanone,[5-(hydroxymethyl)phenyl]phenyl- 3-methyl-1H-pyrrolo[2,3-b]pyridine 3-Methyl-7-azaindole 5654-93-3 Amines Heterocycles Indole Derivatives Intermediates & Fine Chemicals Pharmaceuticals Azaindoles