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4-Methyl-3-oxopentanenitrile

4-Methyl-3-oxopentanenitrile Structure
4-Methyl-3-oxopentanenitrile structure
CAS No.
29509-06-6
Chemical Name:
4-Methyl-3-oxopentanenitrile
Synonyms
EOS-60940;Isobutyrylacetonitrile;4-methyl-3-oxovaleronitrile;Isopropyl cyanomethylketone;4-Methyl-3-oxopentanenitrile;3-Oxo-4-methylpentanenitrile;Pentanenitrile, 4-methyl-3-oxo-;4-Methyl-3-oxopentanenitrile 97+%;Isobutanoylacetonitrile, 4-Methyl-3-oxovaleronitrile;Isobutanoylacetonitrile, 1-Cyano-3-methylbutan-2-one
CBNumber:
CB4395946
Molecular Formula:
C6H9NO
Molecular Weight:
111.14
MDL Number:
MFCD05664144
MOL File:
29509-06-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:48
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4-Methyl-3-oxopentanenitrile Properties

Melting point 62-65 °C
Boiling point 102-104 °C
Density 0.938±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form liquid
pka 9.90±0.10(Predicted)
color Light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H311-H331
Precautionary statements  P261-P280-P301+P310-P311
RIDADR  2810
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  2933599590

4-Methyl-3-oxopentanenitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 283253 4-Methyl-3-oxopentanenitrile Asreported 29509-06-6 500mg $319 2026-06-03 Buy
Usbiological 283253 4-Methyl-3-oxopentanenitrile Asreported 29509-06-6 1g $460 2026-06-03 Buy
Usbiological 283253 4-Methyl-3-oxopentanenitrile Asreported 29509-06-6 2g $602 2026-06-03 Buy
Usbiological 283253 4-Methyl-3-oxopentanenitrile Asreported 29509-06-6 5g $885 2026-06-03 Buy
Usbiological 283253 4-Methyl-3-oxopentanenitrile Asreported 29509-06-6 10g $1238 2026-06-03 Buy
Product number Packaging Price Buy
283253 500mg $319 Buy
283253 1g $460 Buy
283253 2g $602 Buy
283253 5g $885 Buy
283253 10g $1238 Buy

4-Methyl-3-oxopentanenitrile Chemical Properties, Uses, Production

Synthesis

Acetonitrile

75-05-8

Ethyl isobutyrate

97-62-1

4-METHYL-3-OXOPENTANENITRILE

29509-06-6

GENERAL METHOD: Ethyl isobutyrate (6.65 mmol, 1 eq.) was dissolved in THF (30 mL, industrial grade, 0.2% water) at room temperature with stirring at about 230 rpm for 5 minutes. Subsequently, potassium tert-butoxide (1.57 g, 14.0 mmol, 95%, 2 eq.) was rapidly added to the above THF solution. After sufficiently stirring the reaction vial, acetonitrile (6.65 mmol, 1 eq.) was added. The resulting mixture was continued to be stirred at room temperature. Upon completion of the reaction, the reaction was quenched by the addition of water (50 mL) and stirring was continued for 5 minutes. Next, ethyl acetate (40 mL) and HCl solution (1 mL, 12 M) were added, and the organic layer was separated and dried with anhydrous magnesium sulfate. The solvent was removed by evaporation under reduced pressure, and the residue was loaded onto the top of an open silica gel column (column size: 3 × 15 cm, eluent hexane/ethyl acetate (3:1, v/v); for specific products, the column size was adjusted to 3.5 × 8 cm, and the eluent was CH2Cl2). The fraction containing the target product 3-oxo-4-methylpentanenitrile was collected and evaporated under reduced pressure to give the purified β-ketonitrile product.

References

[1] Tetrahedron, 2013, vol. 69, # 48, p. 10331 - 10336
[2] Patent: CN104059024, 2016, B. Location in patent: Paragraph 0061-0064
[3] Organic Letters, 2006, vol. 8, # 6, p. 1161 - 1163
[4] Patent: WO2010/42684, 2010, A1. Location in patent: Page/Page column 57-58
[5] Chemische Berichte, 1982, vol. 115, # 1, p. 355 - 380

4-Methyl-3-oxopentanenitrile Preparation Products And Raw materials

Raw materials

Methyl isobutyrate Acetonitrile Isobutyryl chloride Ethyl isobutyrate Potassium
Tetrahydrofuran Butylate Recombinant Human Telomerase Water

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Preparation Products

Ethyl isobutyrylacetate 3-iso-Propyl-1-phenyl-1H-pyrazol-5-amine 3-Isopropylisoxazol-5-amine

4-Methyl-3-oxopentanenitrile Suppliers

Global Suppliers ( 110)
Supplier Tel Email Country ProdList Advantage
Shandong Juntai Pharmaceutical Co., Ltd 18963498209 18963498209 juntai@h2opharm.com China 289 58
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Aonan chemical technology co.,ltd. info@aonanchem.com China 65 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
Shanghai ChriChem Co., Ltd. 021-54880687 China 510 55
Abblis Chemicals LLC +1-832-373-8299 info@abblis.com United States 322 57
Supplier Advantage
Shandong Juntai Pharmaceutical Co., Ltd 58
Changzhou Huanling Chemical Co., Ltd. 68
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
Nanjing Chemlin Chemical Co., Ltd 64
Syntechem Co.,Ltd 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Aonan chemical technology co.,ltd. 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
Shanghai ChriChem Co., Ltd. 55
Abblis Chemicals LLC 57

View Latest Price from 4-Methyl-3-oxopentanenitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-METHYL-3-OXOPENTANENITRILE pictures 2026-06-30 4-METHYL-3-OXOPENTANENITRILE
29509-06-6
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-METHYL-3-OXOPENTANENITRILE pictures 2025-05-23 4-METHYL-3-OXOPENTANENITRILE
29509-06-6
 $50.00 1kg 99 5000 Hebei Zhuanglai Chemical Trading Co Ltd
4-METHYL-3-OXOPENTANENITRILE pictures 2019-12-26 4-METHYL-3-OXOPENTANENITRILE
29509-06-6
 $1.00 1KG 99% 1000KGS Career Henan Chemical Co

4-Methyl-3-oxopentanenitrile Spectrum

4-METHYL-3-OXOPENTANENITRILE(29509-06-6)1HNMR

29509-06-6 (4-Methyl-3-oxopentanenitrile) Related Search:

Pivaloylacetonitrile 2-(2,2-Dimethylpropanoyl)-3-(4-methoxyphenyl)prop-2-enenitrile 3-Benzo[3,4-d]1,3-dioxolen-5-yl-2-(2,2-dimethylpropanoyl)prop-2-enenitrile 2-(Cyclopropylcarbonyl)-3,3-di(methylthio)acrylonitrile 2-(2,2-Dimethylpropanoyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enenitrile
2-(2,2-Dimethylpropanoyl)-3-(3-phenoxyphenyl)prop-2-enenitrile 2-(2,2-Dimethylpropanoyl)-3-(4-hydroxyphenyl)prop-2-enenitrile 3-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-2-(2,2-dimethylpropanoyl)prop-2-enenitrile 2-(5-Hydroxybenzo[c]2,5-oxathiolen-2-ylidene)-4,4-dimethyl-3-oxopentanenitrile 3-(2-Benzothiazol-2-ylthio-5-nitrophenyl)-2-(2,2-dimethylpropanoyl)prop-2-enenitrile
2-(5-Chloro(3-hydrobenzimidazol-2-ylidene))-4,4-dimethyl-3-oxopentanenitrile 2-(2,2-Dimethylpropanoyl)-3-(4-chlorophenyl)prop-2-enenitrile 2-(2,2-Dimethylpropanoyl)-3-(5-nitro-2-(2-pyridylthio)phenyl)prop-2-enenitrile 3-(4-(Dimethylamino)phenyl)-2-(2,2-dimethylpropanoyl)prop-2-enenitrile 3-((4-(2-Aza-2-methoxy-1-methylvinyl)phenyl)amino)-2-(2,2-dimethylpropanoyl)prop-2-enenitrile
2-(2,2-Dimethylpropanoyl)-3-(4-(trifluoromethoxy)phenyl)prop-2-enenitrile 2-(1,3-Dioxoindan-2-ylidene)-4,4-dimethyl-3-oxopentanenitrile 2-(2,2-Dimethylpropanoyl)-3-((4-phenyl(2,5-thiazolyl))amino)prop-2-enenitrile

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3-Oxo-4-methylpentanenitrile Isobutyrylacetonitrile Isopropyl cyanomethylketone Isobutanoylacetonitrile, 1-Cyano-3-methylbutan-2-one Isobutanoylacetonitrile, 4-Methyl-3-oxovaleronitrile Pentanenitrile, 4-methyl-3-oxo- EOS-60940 4-methyl-3-oxovaleronitrile 4-Methyl-3-oxopentanenitrile 97+% 4-Methyl-3-oxopentanenitrile 29509-06-6