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5-Phenyl-1H-1,2,4-triazol-3-amine

5-Phenyl-1H-1,2,4-triazol-3-amine structure

CAS No.: 4922-98-9

Chemical Name:: 5-Phenyl-1H-1,2,4-triazol-3-amine

Synonyms: NSC 34794;NSC 96969;2-fenil-5-amino-1,3,4-triazolo;4-triazol-3-amine,5-phenyl-1h-2;3-AMINO-5-PHENYL-1,2,4-TRIAZOLE;4-triazole,3-amino-5-phenyl-1h-2;3-Phenyl-1H-1,2,4-triazol-5-amine;5-Phenyl-1H-1,2,4-triazol-3-amine;5-Phenyl-2H-1,2,4-triazole-3-amine;5-Amino-3-phenyl-1H-1,2,4-triazole

CBNumber:: CB4405892

Molecular Formula:: C8H8N4

Molecular Weight:: 160.18

MDL Number:: MFCD00086332

MOL File:: 4922-98-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:52:49

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5-Phenyl-1H-1,2,4-triazol-3-amine Properties

Melting point	191-193℃
Boiling point	276.07°C (rough estimate)
Density	1.315±0.06 g/cm3 (20 ºC 760 Torr)
refractive index	1.5872 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
form	powder to crystal
pka	10.78±0.40(Predicted)
color	Crystals from water
InChI	InChI=1S/C8H8N4/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H,(H3,9,10,11,12)
InChIKey	GHUDJFJZFUVPIQ-UHFFFAOYSA-N
SMILES	N1C(N)=NC(C2=CC=CC=C2)=N1
EWG's Food Scores	1
FDA UNII	QA2L2ED2R9

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes

HazardClass

IRRITANT

HS Code

2922390090

NFPA 704

	0
2		0

5-Phenyl-1H-1,2,4-triazol-3-amine price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	P2658	5-Phenyl-1H-1,2,4-triazol-3-amine	4922-98-9	1G	$102	2026-04-30	Buy
TCI Chemical	P2658	5-Phenyl-1H-1,2,4-triazol-3-amine	4922-98-9	5G	$307	2026-04-30	Buy
TRC	TRC-P336915-1G	5-Phenyl-4h-1,2,4-triazol-3-amine	4922-98-9	1g	$205	2026-06-03	Buy
TRC	TRC-P336915-10G	5-Phenyl-4h-1,2,4-triazol-3-amine	4922-98-9	10g	$1613	2026-06-03	Buy
Apolloscientific	OR307244	3-Phenyl-1H-1,2,4-triazol-5-amine ≥95%	4922-98-9	250mg	$58	2026-06-04	Buy

Product number	Packaging	Price	Buy
P2658	1G	$102	Buy
P2658	5G	$307	Buy
TRC-P336915-1G	1g	$205	Buy
TRC-P336915-10G	10g	$1613	Buy
OR307244	250mg	$58	Buy

5-Phenyl-1H-1,2,4-triazol-3-amine Chemical Properties, Uses, Production

Uses

5-Phenyl-4h-1,2,4-triazol-3-amine, is an intermediate in the synthesis of WP155. 5-Phenyl-4h-1,2,4-triazol-3-amine is also used in biological studies to evaluate its pharmacological activity as it can be applied to a method for reducing susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof.

Safety Profile

Reaction with nitrous acid gives atouch sensitive explosive product. Upon decomposition itemits toxic fumes of NOx.

Synthesis

Benzoicacid, 2-(aminoiminomethyl)hydrazide

3679-92-3

4922-98-9

N-benzamidoguanidine (4.76 g, 26.7 mmol) was used as raw material and dissolved in 40 mL of water. The reaction mixture was heated to 110 °C and refluxed for 6 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to afford the target product 3-phenyl-1H-1,2,4-triazol-5-amine (3.0 g, 18.7 mmol, 70.1% yield).

References

[1] Patent: JP6099045, 2017, B2. Location in patent: Paragraph 0064
[2] Journal of Medicinal Chemistry, 1996, vol. 39, # 15, p. 3019 - 3029
[3] Bioorganic Chemistry, 2013, vol. 50, p. 34 - 40
[4] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 11 - 27
[5] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 774 - 789

5-Phenyl-1H-1,2,4-triazol-3-amine Preparation Products And Raw materials

Raw materials

Benzoicacid, 2-(aminoiminomethyl)hydrazide

Preparation Products

5-(chloromethyl)-2-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one

5-Phenyl-1H-1,2,4-triazol-3-amine Suppliers

Global Suppliers ( 94)

Supplier	Tel	Email	Country	ProdList	Advantage
Chemsigma International Co., Ltd.	02558748998 18951874644	elsa.cheng@chemsigma.com	China	1626	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.	13472757003	yongnan.wang@cendrix.cn	China	974	65
Shanghai Sunway Pharmaceutical Technology Co., Ltd	13761987713	hxzheng@sunwaypharm.cn	China	8663	57
Wuhan Haizheng Industry & Trade Development Co. Ltd	027-8866 0053/88660577/88660578		China	1070	55
Chengdu Forest Science and Technology Development Co., Ltd.	18030648795 18030648795	sales@cdforestchem.com	China	1998	58
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9510	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80

Supplier	Advantage
Chemsigma International Co., Ltd.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Wuhan Chemwish Technology Co., Ltd	56
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.	65
Shanghai Sunway Pharmaceutical Technology Co., Ltd	57
Wuhan Haizheng Industry & Trade Development Co. Ltd	55
Chengdu Forest Science and Technology Development Co., Ltd.	58
Shanghai Topbiochem Technology Co., Ltd	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	80

View Latest Price from 5-Phenyl-1H-1,2,4-triazol-3-amine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-07	5-PHENYL-1H-1,2,4-TRIAZOL-3-AMINE 4922-98-9	$1.00-2.10	1KG	99%	20000KG	Shaanxi Dideu Medichem Co. Ltd

5-PHENYL-1H-1,2,4-TRIAZOL-3-AMINE
4922-98-9
$1.00-2.10
99%
Shaanxi Dideu Medichem Co. Ltd

5-Phenyl-1H-1,2,4-triazol-3-amine Spectrum

5-PHENYL-1H-1,2,4-TRIAZOL-3-AMINE(4922-98-9)¹HNMR 5-PHENYL-1H-1,2,4-TRIAZOL-3-AMINE(4922-98-9)FT-IR

4922-98-9 (5-Phenyl-1H-1,2,4-triazol-3-amine) Related Search:

5-(2-Methylphenyl)-4H-1,2,4-triazol-3-amine 5-(2-Methoxyphenyl)-4H-1,2,4-triazol-3-amine TRIAMIPHOS 5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine 5-(3-Nitrophenyl)-4H-1,2,4-triazol-3-amine

5-(4-Nitrophenyl)-4H-1,2,4-triazol-3-amine 5-(4-Methylphenyl)-4H-1,2,4-triazol-3-amine 5-(4-(Trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-amine 5-(3-(Trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-amine 3-Amino-1,2,4-Triazole

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3-AMINO-5-PHENYL-1,2,4-TRIAZOLE 5-PHENYL-1H-[1,2,4]TRIAZOL-3-YLAMINE 2-fenil-5-amino-1,3,4-triazolo 3-amino-5-phenyl-1h-1,2,4-triazole 4-triazol-3-amine,5-phenyl-1h-2 4-triazole,3-amino-5-phenyl-1h-2 2-Fenil-5-amino-1,3,4-triazolo [Italian] 3-Phenyl-1H-1,2,4-triazole-5-amine 3-Phenyl-5-amino-1H-1,2,4-triazole 5-Amino-3-phenyl-1H-1,2,4-triazole 5-Phenyl-2H-1,2,4-triazole-3-amine 1H-1,2,4-triazol-3-amine, 5-phenyl- 5-phenyl-1H-1,2,4-triazol-3-amine nitrate hydrate NSC 34794 NSC 96969 5-Phenyl-1H-1,2,4-Triazol-3-Amine(WXC04201) 3-Phenyl-1H-1,2,4-triazol-5-amine 1H-1,2,4-Triazol-3-amine, 5-phenyl- (9CI) 1H-1,2,4-Triazole, 3-amino-5-phenyl- 5-Amino-2-phenyl-1H-1,3,4-triazole 1H-1,2,4-Triazol-5-amine, 3-phenyl- 5-phenyl-4H-1,2,4-triazazole-3-amine 5-Phenyl-1H-1,2,4-triazol-3-amine 4922-98-9 C8H8N4HNO3