2-Benzofurancarboxylic acid ethyl ester
- CAS No.
- 3199-61-9
- Chemical Name:
- 2-Benzofurancarboxylic acid ethyl ester
- Synonyms
- BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER;Ethyl CouMarilate;RARECHEM AL BI 0556;Ethyl 2-benzofurancarboxylate;ethyl benzofuran-2-carboxylate;Ethyl 1-benzofuran-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate 97%;BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER;2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER
- CBNumber:
- CB4414494
- Molecular Formula:
- C11H10O3
- Molecular Weight:
- 190.2
- MDL Number:
- MFCD03094950
- MOL File:
- 3199-61-9.mol
- MSDS File:
- SDS
| Melting point | 166-170℃ |
|---|---|
| Boiling point | 105°/0.1mm |
| Density | 1.1656 |
| refractive index | 1.5640 (estimate) |
| Flash point | >110℃ |
| storage temp. | 2-8°C |
| form | solid |
| Appearance | Light brown to brown Solid |
| InChI | 1S/C11H10O3/c1-2-13-11(12)10-7-8-5-3-4-6-9(8)14-10/h3-7H,2H2,1H3 |
| InChIKey | KAWQPOUWLVOHKU-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cc2ccccc2o1 |
| CAS DataBase Reference | 3199-61-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| Hazard Codes | T |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2932190090 |
| Storage Class | 11 - Combustible Solids |
2-Benzofurancarboxylic acid ethyl ester price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 763632 | Ethyl benzofuran-2-carboxylate 97% | 3199-61-9 | 1g | $30.2 | 2023-06-20 | Buy |
| Usbiological | 263898 | Benzofuran-2-carboxylic acid ethyl ester Asreported | 3199-61-9 | 250mg | $355 | 2026-06-03 | Buy |
| Usbiological | 263898 | Benzofuran-2-carboxylic acid ethyl ester Asreported | 3199-61-9 | 500mg | $502 | 2026-06-03 | Buy |
| Usbiological | 263898 | Benzofuran-2-carboxylic acid ethyl ester Asreported | 3199-61-9 | 1g | $686 | 2026-06-03 | Buy |
| Usbiological | 263898 | Benzofuran-2-carboxylic acid ethyl ester Asreported | 3199-61-9 | 2g | $995 | 2026-06-03 | Buy |
2-Benzofurancarboxylic acid ethyl ester Chemical Properties,Uses,Production
Uses
Ethyl Coumarilate has been used as a reactant for the preparation of benzofuropyridines that have a high affinity for the α2-adrenoceptor.
Preparation
Synthesis of ethyl benzofuran-2-carboxylate: Salicylaldehyde (20.0 mL, 0.164 mol) and diethyl bromomalonate (40.0 mL, 0.168 mol) in ethyl methyl ketone (40.0 mL, 0.555 mol) was treated with anhydrous potassium carbonate (20.0 g,0.869 mol). The reaction mixture was refluxed for 18 h on steam bath. Ethyl methyl ketone was distilled off under reduced pressure and the residue formed was dissolved in 400 mL of water and cooled in an ice-bath. It was acidified with dil H2SO4. The product formed was extracted with 25 mL portion of solvent ether twice and the extract was washed with sodium bicarbonate solution. It was dried over calcium chloride. Solvent was removed and the residue ethyl benzofuran-2-carboxylate was dried.
Synthesis Reference(s)
Tetrahedron Letters, 27, p. 6315, 1986 DOI: 10.1016/S0040-4039(00)87796-5
2-Benzofurancarboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Yangzhou Siyu Chemical Co.,Ltd. | 0514-87325867 | sales@siyuchem.com | China | 370 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
View Lastest Price from 2-Benzofurancarboxylic acid ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-09 | 2-Benzofurancarboxylic acid ethyl ester
3199-61-9
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-10 | 2-Benzofurancarboxylic acid ethyl ester
3199-61-9
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-Benzofurancarboxylic acid ethyl ester
3199-61-9
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Benzofurancarboxylic acid ethyl ester
3199-61-9
- $7.00
- 99%
- Career Henan Chemical Co
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