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7-Benzyloxy-4-chloroquinoline

7-Benzyloxy-4-chloroquinoline structure

CAS No.: 178984-56-0

Chemical Name:: 7-Benzyloxy-4-chloroquinoline

Synonyms: 102579;4-chloro-7-(phenylMethoxy;4-chloro-7-benzoxyquinoline;4-chloro-7-phenoxy-quinoline;7-Benzyloxy-4-chloroquinoline;4-chloro-7-phenylmethoxyquinoline;Quinoline, 4-chloro-7-(phenylmethoxy)-;7-BENZYLOXY-4-CHLOROQUINOLINE ISO 9001：2015 REACH

CBNumber:: CB4420424

Molecular Formula:: C16H12ClNO

Molecular Weight:: 269.73

MDL Number:: MFCD06659039

MOL File:: 178984-56-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:49

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7-Benzyloxy-4-chloroquinoline Properties

Boiling point	414.1±30.0 °C(Predicted)
Density	1.263±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	3.86±0.27(Predicted)
Appearance	White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

7-Benzyloxy-4-chloroquinoline price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	072748	7-(Benzyloxy)-4-chloroquinoline	178984-56-0	250.00mg	$231	2026-05-18	Buy
Matrix Scientific	072748	7-(Benzyloxy)-4-chloroquinoline	178984-56-0	1.00g	$500	2026-05-18	Buy
Matrix Scientific	072748	7-(Benzyloxy)-4-chloroquinoline	178984-56-0	5.00g	$1428	2026-05-18	Buy
aablocks	AA0026L7	7-(Benzyloxy)-4-chloroquinoline 97%	178984-56-0	1g	$33	2026-05-28	Buy
aablocks	AA0026L7	7-(Benzyloxy)-4-chloroquinoline 97%	178984-56-0	5g	$116	2026-05-28	Buy

Product number	Packaging	Price	Buy
072748	250.00mg	$231	Buy
072748	1.00g	$500	Buy
072748	5.00g	$1428	Buy
AA0026L7	1g	$33	Buy
AA0026L7	5g	$116	Buy

7-Benzyloxy-4-chloroquinoline Chemical Properties, Uses, Production

Synthesis

749922-34-7

178984-56-0

Step 3) Synthesis of 7-(benzyloxy)-4-chloroquinoline: 7-(benzyloxy)quinolin-4-ol (72 g, 287 mmol) was suspended in toluene (134 mL), and phosphorus trichloride (44 g, 287 mmol, source: Tianjin FuChen Chem. Co. Ltd.) was added. The suspension was heated to 120 °C and maintained for 1 hour. After completion of the reaction, the mixture was cooled to 70 °C and diluted with EtOAc (600 mL). The resulting mixture was stirred in an ice bath for 30 min and cooled to 15 °C. Subsequently, the mixture was neutralized with 3M NaOH aqueous solution to pH 7~8, keeping the solution temperature below 20°C during the process. The aqueous layer was separated and the organic layer was extracted with EtOAc. The combined organic layers were washed with brine (200 mL), dried over anhydrous Na2SO4, and concentrated in vacuum to give 7-benzyloxy-4-chloroquinoline as a light yellow solid (70.8 g, 91.6% yield). Mass spectrum (ESI, positive ion mode) m/z: 270.1 [M + 1]; 1H NMR (400 MHz, DMSO-d6) δ: 5.31 (s, 2H), 7.35 (t, 1H), 7.42 (t, J = 7.2Hz, 2H), 7.47 (dd, J = 2.8Hz, J = 9.2Hz, 1H), 7.52 (d, J = 7.6 Hz, 2H), 7.13 (t, J = 4.8 Hz, 2H), 8.11 (d, J = 9.6 Hz, 1H), 8.75 (d, J = 4.8 Hz, 1H).

References

[1] Patent: US2012/219522, 2012, A1. Location in patent: Page/Page column 20

7-Benzyloxy-4-chloroquinoline Preparation Products And Raw materials

Raw materials

4-Chloro-7-hydroxyquinoline 7-Benzyloxy-4-hydroxy-quinoline Benzyl bromide Toluene trichlorophosphate

Preparation Products

7-Benzyloxy-4-chloroquinoline Suppliers

Global Suppliers ( 80)

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Ennopharm Co., Ltd.	+86 (21) 6435-5022		China	4263	65
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57
ChemShuttle, Inc.	0510-83588313-811 18800520310	sales@chemshuttle.com	China	2999	62
SembCorp Shenzhenshibai a Biotechnology Co., Ltd	13412890622		China	23	55
Wuhan Kaymke Chemical Co., Ltd.,	027-87342388 18086026008	sales@kaymke.com	China	3537	55
Shanghai Carlow Chemicals Co., Ltd.	21-33526724 18930996265	info@carlowchem.com	China	1996	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Jiaxing Novartis Chemical Co., Ltd.	18957373295		China	1579	58

Supplier	Advantage
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Ennopharm Co., Ltd.	65
Syntechem Co.,Ltd	57
ChemShuttle, Inc.	62
SembCorp Shenzhenshibai a Biotechnology Co., Ltd	55
Wuhan Kaymke Chemical Co., Ltd.,	55
Shanghai Carlow Chemicals Co., Ltd.	58
Bide Pharmatech Ltd.	60
Jiaxing Novartis Chemical Co., Ltd.	58

View Latest Price from 7-Benzyloxy-4-chloroquinoline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	7-BENZYLOXY-4-CHLOROQUINOLINE 178984-56-0	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2019-07-06	7-BENZYLOXY-4-CHLOROQUINOLINE 178984-56-0	$6.00	1KG	99%		Career Henan Chemical Co

7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
$1.10
99.00%
Dideu Industries Group Limited

7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
$6.00
99%
Career Henan Chemical Co

7-Benzyloxy-4-chloroquinoline Spectrum

7-BENZYLOXY-4-CHLOROQUINOLINE(178984-56-0)¹HNMR

178984-56-0 (7-Benzyloxy-4-chloroquinoline) Related Search:

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4-chloro-7-benzoxyquinoline 4-chloro-7-(phenylMethoxy 4-chloro-7-phenoxy-quinoline 4-chloro-7-phenylmethoxyquinoline 102579 Quinoline, 4-chloro-7-(phenylmethoxy)- 7-BENZYLOXY-4-CHLOROQUINOLINE ISO 9001：2015 REACH 7-Benzyloxy-4-chloroquinoline 178984-56-0