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β-Ht 920 dihydrochloride

β-Ht 920 dihydrochloride Structure
β-Ht 920 dihydrochloride structure
CAS No.
36085-73-1
Chemical Name:
β-Ht 920 dihydrochloride
Synonyms
Talipexole HCl;b-ht920;4H-Thiazolo[4;B-HT 920 2HCl;Talipexole 2HCl;5-d]azepin-2-aMine;hydrochloride (1:2);Hydrochloric talipexole;talipexole hydrochloride;B-HT 920 (hydrochloride)
CBNumber:
CB4437406
Molecular Formula:
C10H17Cl2N3S
Molecular Weight:
282.23
MDL Number:
MFCD00274573
MOL File:
36085-73-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:49
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β-Ht 920 dihydrochloride Properties

Melting point 245°C dec.
storage temp. Desiccate at RT
solubility H2O: >20 mg/mL
form solid
color off-white
EWG's Food Scores 1
FDA UNII 9R6E1D8H1O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  XJ7050340
NFPA 704
0
2 0

β-Ht 920 dihydrochloride price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 5mg $75 2026-04-30 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 10mg $134 2026-04-30 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 50mg $553 2026-04-30 Buy
Usbiological 254699 B-HT 920 Asreported 36085-73-1 10mg $389 2026-06-03 Buy
Usbiological 254699 B-HT 920 Asreported 36085-73-1 50mg $955 2026-06-03 Buy
Product number Packaging Price Buy
14177 5mg $75 Buy
14177 10mg $134 Buy
14177 50mg $553 Buy
254699 10mg $389 Buy
254699 50mg $955 Buy

β-Ht 920 dihydrochloride Chemical Properties, Uses, Production

Description

B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors.

Chemical Properties

B-HT 920 DIHYDROCHLORIDE is Light Yellow Solid

Uses

B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent

Definition

ChEBI: Talipexole dihydrochloride is an azepine.

Biological Activity

Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity.

References

[1] FRANCIS K. MAINA  Tiffany A M. Functional Fast Scan Cyclic Voltammetry Assay to Characterize Dopamine D2 and D3 Autoreceptors in the Mouse Striatum[J]. ACS Chemical Neuroscience, 2010, 1 6: 450-462. DOI: 10.1021/cn100003u
[2] RICHARD E. MEWSHAW. New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. StructureActivity Relationships of a Series of 2-(Aminomethyl)chromans[J]. Journal of Medicinal Chemistry, 1997, 40 26: 4235-4256. DOI: 10.1021/jm9703653
[3] G S ROBERTSON. In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release.[J]. Journal of Pharmacology and Experimental Therapeutics, 1993, 264 3: 1344-1351.
[4] KITAMURA Y. [Dopaminergic neuroprotection and reconstruction of neural network tiara].[J]. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 2010, 130 10: 1263-1272. DOI: 10.1248/yakushi.130.1263
[5] HIROAKI NISHIO . 5-HT3 receptor blocking properties of the antiparkinsonian agent, talipexole[J]. General Pharmacology-the Vascular System, 1996, 27 5: Pages 779-785. DOI: 10.1016/0306-3623(95)02125-6
[6] DANIEL RICCI  Carlos A T. Adrenoceptor Involvement in the Cardiovascular Responses to B-HT 920 in Sinoaortic Denervated Rats[J]. General Pharmacology-the Vascular System, 1999, 32 1: Pages 29-34. DOI: 10.1016/s0306-3623(98)00018-4

β-Ht 920 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

β-Ht 920 dihydrochloride Suppliers

Global Suppliers ( 118)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6742 52
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chembest Research Laboratories Limited 61
Capot Chemical Co., Ltd 66
Pure Chemistry Scientific Inc. 62
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
Shanghai Sphchem Co., Ltd. 55
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58

View Latest Price from β-Ht 920 dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Talipexole dihydrochloride pictures 2026-07-27 Talipexole dihydrochloride
36085-73-1
 $30.00-73.00 99.89% 10g TargetMol Chemicals Inc.
Talipexole dihydrochloride pictures 2026-07-27 Talipexole dihydrochloride
36085-73-1
 $30.00-73.00 99.89% 10g TargetMol Chemicals Inc.

β-Ht 920 dihydrochloride Spectrum

B-HT 920 DIHYDROCHLORIDE(36085-73-1)1HNMR

36085-73-1 (β-Ht 920 dihydrochloride) Related Search:

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Trimetazidine dihydrochloride TALIPEXOLE

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5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amineDihydrochloride,6-Allyl-2-amino-5,6,7,8-tetrahydro-4 B-HT920dihydrochlorideTalipexole 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d] azepin-2-amine dihydrochloride talipexole hydrochloride 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride 2-Amino-6-allyl-4,5,7,8-tetrahydro-6H-thiazolo(5,4-D)azepin-dihydrochlorid [german] 4H-Thiazolo(4,5-D)azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propenyl)-, dihydrochloride 4H-Thiazolo[4 5-d]azepin-2-aMine 8-tetrahydro-6-(2-propen-1-yl)- hydrochloride (1:2) Talipexole dihydrochloride(B-HT 920) B-HT 920 2HCl Hydrochloric talipexole B-HT 920 (hydrochloride) TALIPEXOLE DIDHYDROCHLORIDE 2-amino-6-allyl-4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepin-dihydrochlorid 5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(4,5-d)azepin-2-aminedihydrochl 5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(dihydroch b-ht920 talipexoledihydrochloride 6-ALLYL-2-AMINO-5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE DIHYDROCHLORIDE 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPIN-2-AMINE DIHYDROCHLORIDE 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPINE-2-AMINE DIHYDROCHLORIDE B-HT 920 DIHYDROCHLORIDE A2 ADRENOCEPTOR AGONI B-HT 920 Dihydrochloride\nTalipexole 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride 6-Allyl-5,6,7,8-tetrahydro-4H-thiazole [4,5-d] aza-2-amine dihydrochloride 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-, hydrochloride (1:2) Talipexole 2HCl Talipexole dihydrochloride, 10 mM in DMSO Talipexole HCl β-Ht 920 dihydrochloride 36085-73-1 C10H17Cl2N3S C10H15N3S2HCl Adrenoceptor All Inhibitors Inhibitors Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals