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B-HT 920 DIHYDROCHLORIDE

B-HT 920 DIHYDROCHLORIDE Structure
B-HT 920 DIHYDROCHLORIDE structure
CAS No.
36085-73-1
Chemical Name:
B-HT 920 DIHYDROCHLORIDE
Synonyms
Talipexole HCl;b-ht920;4H-Thiazolo[4;B-HT 920 2HCl;Talipexole 2HCl;5-d]azepin-2-aMine;hydrochloride (1:2);Hydrochloric talipexole;talipexole hydrochloride;B-HT 920 (hydrochloride)
CBNumber:
CB4437406
Molecular Formula:
C10H17Cl2N3S
Molecular Weight:
282.23
MDL Number:
MFCD00274573
MOL File:
36085-73-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:10:55
Product description Number Pack Size Price
B-HT 920 (hydrochloride) ≥95% 14177 5mg $75
B-HT 920 (hydrochloride) ≥95% 14177 10mg $134
B-HT 920 (hydrochloride) ≥95% 14177 50mg $553
B-HT 920 (hydrochloride) ≥95% 14177 5mg $68
B-HT 920 (hydrochloride) ≥95% 14177 10mg $121
More product size
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B-HT 920 DIHYDROCHLORIDE Properties

Melting point 245°C dec.
storage temp. Desiccate at RT
solubility H2O: >20 mg/mL
form solid
color off-white
EWG's Food Scores 1
FDA UNII 9R6E1D8H1O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  XJ7050340
NFPA 704
0
2 0

B-HT 920 DIHYDROCHLORIDE price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 5mg $75 2026-04-30 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 10mg $134 2026-04-30 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 50mg $553 2026-04-30 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 5mg $68 2024-03-01 Buy
Cayman Chemical 14177 B-HT 920 (hydrochloride) ≥95% 36085-73-1 10mg $121 2024-03-01 Buy
Product number Packaging Price Buy
14177 5mg $75 Buy
14177 10mg $134 Buy
14177 50mg $553 Buy
14177 5mg $68 Buy
14177 10mg $121 Buy

B-HT 920 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Description

B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors.

Chemical Properties

B-HT 920 DIHYDROCHLORIDE is Light Yellow Solid

Uses

B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent

Definition

ChEBI: Talipexole dihydrochloride is an azepine.

Biological Activity

Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity.

References

[1] FRANCIS K. MAINA  Tiffany A M. Functional Fast Scan Cyclic Voltammetry Assay to Characterize Dopamine D2 and D3 Autoreceptors in the Mouse Striatum[J]. ACS Chemical Neuroscience, 2010, 1 6: 450-462. DOI: 10.1021/cn100003u
[2] RICHARD E. MEWSHAW. New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. StructureActivity Relationships of a Series of 2-(Aminomethyl)chromans[J]. Journal of Medicinal Chemistry, 1997, 40 26: 4235-4256. DOI: 10.1021/jm9703653
[3] G S ROBERTSON. In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release.[J]. Journal of Pharmacology and Experimental Therapeutics, 1993, 264 3: 1344-1351.
[4] KITAMURA Y. [Dopaminergic neuroprotection and reconstruction of neural network tiara].[J]. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 2010, 130 10: 1263-1272. DOI: 10.1248/yakushi.130.1263
[5] HIROAKI NISHIO . 5-HT3 receptor blocking properties of the antiparkinsonian agent, talipexole[J]. General Pharmacology-the Vascular System, 1996, 27 5: Pages 779-785. DOI: 10.1016/0306-3623(95)02125-6
[6] DANIEL RICCI  Carlos A T. Adrenoceptor Involvement in the Cardiovascular Responses to B-HT 920 in Sinoaortic Denervated Rats[J]. General Pharmacology-the Vascular System, 1999, 32 1: Pages 29-34. DOI: 10.1016/s0306-3623(98)00018-4

B-HT 920 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

B-HT 920 DIHYDROCHLORIDE Suppliers

Global( 119)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 9563 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LUYUNJIA CHEMISTRY XIAMEN LIMITED 		+86-592-5360779 +86-13055435203 China 5988 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39037 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
CONIER CHEM AND PHARMA LIMITED 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
InvivoChem 		58
LUYUNJIA CHEMISTRY XIAMEN LIMITED 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from B-HT 920 DIHYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Talipexole dihydrochloride pictures 2026-05-11 Talipexole dihydrochloride
36085-73-1
 $30.00-73.00 99.89% 10g TargetMol Chemicals Inc.
Talipexole dihydrochloride pictures 2026-04-22 Talipexole dihydrochloride
36085-73-1
 $30.00-73.00 99.89% 10g TargetMol Chemicals Inc.

B-HT 920 DIHYDROCHLORIDE Spectrum

B-HT 920 DIHYDROCHLORIDE(36085-73-1)1HNMR

36085-73-1(B-HT 920 DIHYDROCHLORIDE)Related Search:

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5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amineDihydrochloride,6-Allyl-2-amino-5,6,7,8-tetrahydro-4 B-HT920dihydrochlorideTalipexole 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d] azepin-2-amine dihydrochloride talipexole hydrochloride 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride 2-Amino-6-allyl-4,5,7,8-tetrahydro-6H-thiazolo(5,4-D)azepin-dihydrochlorid [german] 4H-Thiazolo(4,5-D)azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propenyl)-, dihydrochloride 4H-Thiazolo[4 5-d]azepin-2-aMine 8-tetrahydro-6-(2-propen-1-yl)- hydrochloride (1:2) Talipexole dihydrochloride(B-HT 920) B-HT 920 2HCl Hydrochloric talipexole B-HT 920 (hydrochloride) TALIPEXOLE DIDHYDROCHLORIDE 2-amino-6-allyl-4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepin-dihydrochlorid 5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(4,5-d)azepin-2-aminedihydrochl 5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-(2-propenyl)-4h-thiazolo(dihydroch b-ht920 talipexoledihydrochloride 6-ALLYL-2-AMINO-5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE DIHYDROCHLORIDE 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPIN-2-AMINE DIHYDROCHLORIDE 5,6,7,8-TETRAHYDRO-6-(2-PROPENYL)-4H-THIAZOLO[4,5-D]AZEPINE-2-AMINE DIHYDROCHLORIDE B-HT 920 DIHYDROCHLORIDE B-HT 920 DIHYDROCHLORIDE A2 ADRENOCEPTOR AGONI B-HT 920 Dihydrochloride\nTalipexole 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride 6-Allyl-5,6,7,8-tetrahydro-4H-thiazole [4,5-d] aza-2-amine dihydrochloride 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-, hydrochloride (1:2) Talipexole 2HCl Talipexole dihydrochloride, 10 mM in DMSO Talipexole HCl 36085-73-1 C10H17Cl2N3S C10H15N3S2HCl Adrenoceptor All Inhibitors Inhibitors Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals