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PAT-1251

PAT-1251 Structure
PAT-1251 structure
CAS No.
2007885-39-2
Chemical Name:
PAT-1251
Synonyms
PAT 1251,PAT1251;Lenumlostat (PAT-1251);PAT-1251, 10 mM in DMSO;rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone;Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-
CBNumber:
CB44797092
Molecular Formula:
C18H17F4N3O3
Molecular Weight:
399.34
MDL Number:
MOL File:
2007885-39-2.mol
Last updated:2025-09-23 13:47:07
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PAT-1251 Properties

Boiling point 540.7±50.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 130 mg/mL (325.54 mM)
form Solid
pka 13.23±0.40(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

PAT-1251 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0028450 PAT-1251 98.17% 2007885-39-2 5mg $650 2021-12-16 Buy
ChemScene CS-0028450 PAT-1251 98.17% 2007885-39-2 10mg $950 2021-12-16 Buy
ChemScene CS-0028450 PAT-1251 98.17% 2007885-39-2 25mg $1950 2021-12-16 Buy
ChemScene CS-0028450 PAT-1251 98.17% 2007885-39-2 50mg $2950 2021-12-16 Buy
ChemScene CS-0028450 PAT-1251 98.17% 2007885-39-2 100mg $4500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0028450 5mg $650 Buy
CS-0028450 10mg $950 Buy
CS-0028450 25mg $1950 Buy
CS-0028450 50mg $2950 Buy
CS-0028450 100mg $4500 Buy

PAT-1251 Chemical Properties,Uses,Production

Uses

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases[1].

References

[1] Rowbottom MW, et al. Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2). J Med Chem. 2017 May 25;60(10):4403-4423. DOI:10.1021/acs.jmedchem.7b00345

PAT-1251 Preparation Products And Raw materials

Raw materials

Preparation Products

PAT-1251 Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32432 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39031 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2382 58
Chengdu Saint - Kay Biotechnology Co., Ltd. 028-85157043 15882256948 676046971@qq.com China 4176 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278 YN_research@163.com China 3003 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 sales@hasunny.com China 2380 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24989 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Chengdu Novel Biomedical Co., Ltd. 58
Chengdu Saint - Kay Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
Shanghai hongqu biomedical technology co. LTD 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
TargetMol Chemicals Inc. 58

View Lastest Price from PAT-1251 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PAT-1251 pictures 2025-09-23 PAT-1251
2007885-39-2
 US $66.00-255.00 / mg 99.78% 10g TargetMol Chemicals Inc.
PAT-1251 pictures 2025-09-23 PAT-1251
2007885-39-2
 US $66.00-255.00 / mg 99.78% 10g TargetMol Chemicals Inc.
  • PAT-1251 pictures
  • PAT-1251
    2007885-39-2
  • US $66.00-255.00 / mg
  • 99.78%
  • TargetMol Chemicals Inc.
  • PAT-1251 pictures
  • PAT-1251
    2007885-39-2
  • US $66.00-255.00 / mg
  • 99.78%
  • TargetMol Chemicals Inc.
Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel- PAT 1251,PAT1251 rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone PAT-1251, 10 mM in DMSO Lenumlostat (PAT-1251) 2007885-39-2