PAT-1251
- CAS No.
- 2007885-39-2
- Chemical Name:
- PAT-1251
- Synonyms
- PAT 1251,PAT1251;Lenumlostat (PAT-1251);PAT-1251, 10 mM in DMSO;rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone;Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-
- CBNumber:
- CB44797092
- Molecular Formula:
- C18H17F4N3O3
- Molecular Weight:
- 399.34
- MDL Number:
- MOL File:
- 2007885-39-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
PAT-1251 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | HFD88539 | PAT-1251 | 2007885-39-2 | 5mg | $812.6 | 2026-06-04 | Buy |
| Biosynth | HFD88539 | PAT-1251 | 2007885-39-2 | 10mg | $1300.1 | 2026-06-04 | Buy |
| Biosynth | HFD88539 | PAT-1251 | 2007885-39-2 | 25mg | $2119.5 | 2026-06-04 | Buy |
| Biosynth | HFD88539 | PAT-1251 | 2007885-39-2 | 50mg | $3392 | 2026-06-04 | Buy |
| ChemScene | CS-0028450 | Lenumlostat 99.52% | 2007885-39-2 | 5mg | $211 | 2026-06-04 | Buy |
PAT-1251 Chemical Properties, Uses, Production
Uses
PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases[1].
References
[1] Rowbottom MW, et al. Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2). J Med Chem. 2017 May 25;60(10):4403-4423. DOI:10.1021/acs.jmedchem.7b00345
PAT-1251 Preparation Products And Raw materials
Raw materials
Preparation Products
PAT-1251 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2445 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4183 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
