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4-Hydroxy 4-Dedimethylamino Afatinib

4-Hydroxy 4-Dedimethylamino Afatinib Structure
4-Hydroxy 4-Dedimethylamino Afatinib structure
CAS No.
2121530-37-6
Chemical Name:
4-Hydroxy 4-Dedimethylamino Afatinib
Synonyms
RMA-811;Lansoprazole Impurity 73;Afatinib 4-Hydroxy Analog;1,3-dimethyl-52-nitrosourea;Afatinib Maleate Acid Impurity 3;4-Hydroxy 4-Dedimethylamino Afatinib;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-;(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide;Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
CBNumber:
CB44806714
Molecular Formula:
C22H20ClFN4O4
Molecular Weight:
458.87
MDL Number:
MOL File:
2121530-37-6.mol
Last updated:2025-07-04 15:20:47
Product description Number Pack Size Price
(2E)​-N-​[4-​[(3-​chloro-​4-​fluorophenyl)​amino]​-​7-​[[(3S)​-​tetrahydro-​3-​furanyl]​oxy]​-​6-​quinazolinyl]​-​4-​hydroxy-2-​butenamide C376205 25mg $690
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4-Hydroxy 4-Dedimethylamino Afatinib Properties

Boiling point 714.713±60.00 °C(Press: 760.00 Torr)(predicted)
Density 1.484±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 11.521±0.43(predicted)
InChIKey XZMUSENASPIMAT-YUKKFKLSSA-N
SMILES N(C1C=CC(=C(C=1)Cl)F)C1=NC=NC2C=C(C(=CC=21)NC(=O)/C=C/CO)O[C@@H]1COCC1

4-Hydroxy 4-Dedimethylamino Afatinib price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C376205 (2E)​-N-​[4-​[(3-​chloro-​4-​fluorophenyl)​amino]​-​7-​[[(3S)​-​tetrahydro-​3-​furanyl]​oxy]​-​6-​quinazolinyl]​-​4-​hydroxy-2-​butenamide 2121530-37-6 25mg $690 2021-12-16 Buy
Product number Packaging Price Buy
C376205 25mg $690 Buy

4-Hydroxy 4-Dedimethylamino Afatinib Chemical Properties,Uses,Production

Uses

(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide is an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Hydroxy 4-Dedimethylamino Afatinib Preparation Products And Raw materials

Raw materials

Preparation Products

4-Hydroxy 4-Dedimethylamino Afatinib Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Puster Biotechnology Co., Ltd 15001877879 894058805@qq.com China 64 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7912 65
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4757 55
Shanghai CR Corporation Limited 13062833949; 13062833949 fred.wen@crcorporation.cn China 9786 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679; 13502246435 3008233746@qq.com China 9965 12
Hubei Xinyang Medical Technology Co., Ltd 15347293736 2853117764@yongstandards.com China 9999 58
NANJING WEDO PHARMATECH CO.,LTD. 15189836218 wedo-chem@huawe.com China 240 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 15921286451; 15921286451 2010681527@qq.com China 4915 58
Shenzhen Excellent Biomedical Technology Co., Ltd. 0755-26050679 18318671572 2850803126@qq.com China 9992 58
https://www.shachemlin.cn/ 68080707 15021879576 ming-jiao.wu@chemlin.com.cn China 9050 58
Supplier Advantage
Suzhou Puster Biotechnology Co., Ltd 58
Daicel Chiral Technologies (China)CO.,LTD 65
Nanjing XiZe Biotechnology CO., Ltd. 55
Shanghai CR Corporation Limited 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 12
Hubei Xinyang Medical Technology Co., Ltd 58
NANJING WEDO PHARMATECH CO.,LTD. 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 58
Shenzhen Excellent Biomedical Technology Co., Ltd. 58
https://www.shachemlin.cn/ 58

View Lastest Price from 4-Hydroxy 4-Dedimethylamino Afatinib manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Afatinib Impurity pictures 2025-12-16 Afatinib Impurity
2121530-37-6
 10mg 98 10000 Moxin Chemicals

2121530-37-6(4-Hydroxy 4-Dedimethylamino Afatinib)Related Search:

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4-Hydroxy 4-Dedimethylamino Afatinib Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide Afatinib 4-Hydroxy Analog Afatinib Maleate Acid Impurity 3 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)- (2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide 1,3-dimethyl-52-nitrosourea Lansoprazole Impurity 73 RMA-811 2121530-37-6