PAR3 (1-6) amide (mouse) (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- PAR3 (1-6) amide (mouse) (trifluoroacetate salt)
- Synonyms
- PAR3 (1-6) amide (mouse) (trifluoroacetate salt)
- CBNumber:
- CB44815013
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
PAR3 (1-6) amide (mouse) (trifluoroacetate salt) price More Price(2)
PAR3 (1-6) amide (mouse) (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
PAR3 (1-6) amide is a synthetic hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse proteinase-activated receptor 3 (PAR3) and residues 38-43 of the full-length sequence. PAR3 (1-6) amide activates PAR1 and PAR2, but not PAR3 or PAR4.1,2 It does not induce thrombin signaling in COS-7 cells expressing PAR3, PAR4, or both receptors at concentrations less than or equal to 500 µM, however, it does activate PAR1 and PAR2 in a cross-desensitization assay in Jurkat T cells when used at concentrations of 500 and 1,000 µM.1,2 PAR3 (1-6) increases calcium levels in Kirsten virus-transformed rat kidney (KNRK) cells expressing rat or human PAR2, with a higher potency for rat PAR2.WARNING This product is not for human or veterinary use.
References
[1] MAYUMI NAKANISHI-MATSUI. PAR3 is a cofactor for PAR4 activation by thrombin[J]. Nature, 2000, 404 6778: 609-613. DOI: 10.1038/35007085
[2] KRISTINA K. HANSEN Morley D H Mahmoud Saifeddine. Tethered ligand-derived peptides of proteinase-activated receptor 3 (PAR3) activate PAR1 and PAR2 in Jurkat T cells[J]. Immunology, 2004, 112 2: 183-190. DOI: 10.1111/j.1365-2567.2004.01870.x
PAR3 (1-6) amide (mouse) (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
PAR3 (1-6) amide (mouse) (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
