Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>N-Nitroso-N-Methyl-4-Aminobutyric Acid

N-Nitroso-N-Methyl-4-Aminobutyric Acid

N-Nitroso-N-Methyl-4-Aminobutyric Acid Structure
N-Nitroso-N-Methyl-4-Aminobutyric Acid structure
CAS No.
61445-55-4
Chemical Name:
N-Nitroso-N-Methyl-4-Aminobutyric Acid
Synonyms
NMBA;4-(Methylnitrosoamino)butanoic acid;N56-004;Losartan Impurity 17;Losartan Impurity 41;Azisartan Impurity 102;Azilsartan Impurity 102;Nitrosoamine MCP Impurity;Rosuvastatin Impurity 186;Losartan genotoxic impurity
CBNumber:
CB4482471
Molecular Formula:
C5H10N2O3
Molecular Weight:
146.14
MDL Number:
MFCD00869939
MOL File:
61445-55-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 30911 10mg $141
N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 30911 25mg $317
N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 30911 50mg $599
N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 30911 100mg $1127
N-Nitroso-N-methyl-4-aminobutyric Acid >95%(HPLC) TRC-N529000-25MG 25mg $381
Request For Quotation

N-Nitroso-N-Methyl-4-Aminobutyric Acid Properties

Melting point >25 °C
Boiling point 265.74°C (rough estimate)
Density 1.3394 (rough estimate)
refractive index 1.4954 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Soluble), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
form Solid
pka 4.57±0.10(Predicted)
color Off-White to Yellow
Stability Hygroscopic
Major Application pharmaceutical (small molecules)
InChI InChI=1S/C5H10N2O3/c1-7(6-10)4-2-3-5(8)9/h2-4H2,1H3,(H,8,9)
InChIKey SJLBIPLIGYWGJV-UHFFFAOYSA-N
SMILES C(O)(=O)CCCN(C)N=O
FDA UNII 7K7252TZ54
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)Exclamation Mark (GHS07)Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS08,GHS07,GHS05,GHS06
Signal word  Danger
Hazard statements  H351-H301-H335-H318-H315-H361
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501
WGK Germany  WGK 2
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
NFPA 704
0
3 0

N-Nitroso-N-Methyl-4-Aminobutyric Acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30911 N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 61445-55-4 10mg $141 2026-04-30 Buy
Cayman Chemical 30911 N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 61445-55-4 25mg $317 2026-04-30 Buy
Cayman Chemical 30911 N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 61445-55-4 50mg $599 2026-04-30 Buy
Cayman Chemical 30911 N-Nitroso-N-methyl-4-Aminobutyric Acid ≥95% 61445-55-4 100mg $1127 2026-04-30 Buy
TRC TRC-N529000-25MG N-Nitroso-N-methyl-4-aminobutyric Acid >95%(HPLC) 61445-55-4 25mg $381 2026-06-03 Buy
Product number Packaging Price Buy
30911 10mg $141 Buy
30911 25mg $317 Buy
30911 50mg $599 Buy
30911 100mg $1127 Buy
TRC-N529000-25MG 25mg $381 Buy

N-Nitroso-N-Methyl-4-Aminobutyric Acid Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

Uses

N-Nitroso-N-methyl-4-aminobutyric acid EP reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.
It is also used to prepare N-Nitrosamines spiking solution to detect the concentration of N-nitrosamines in active substances by liquid chromatography coupled with mass spectrometry according to the monograph 20542of European Pharmacopoeia.

Definition

ChEBI: N-nitroso-N-methyl-4-aminobutyric acid is a nitrosamine that has methyl and 3-carboxypropyl substituents. It is a tobacco-derived nitrosamino acid that is a known animal and potential human carcinogen. It induces bladder transitional cell carcinomas in rats and has recently been identified as a contaminant in certain blood pressure medications. It has a role as a carcinogenic agent, a rat metabolite, a xenobiotic metabolite and a plant metabolite. It is a monocarboxylic acid and a nitrosamine.

Synthesis

Add 5.0 g (0.05 mol) of N-methylpyrrolidone to a 250 mL four-necked flask, add 50 g of toluene and stir to dissolve clear, . Add 0.5 g of tetrabutylammonium bromide, add aqueous sodium hydroxide solution (sodium hydroxide: 4 g (0.1 mol); water: 40 g), raise temperature to 50 , stirring reaction 28h, liquid separation, organic phase discarded, aqueous phase with hydrochloric acid to adjust pH = 1.0, filtration, filtrate collection, filter cake discarded.

N-Nitroso-N-Methyl-4-Aminobutyric Acid synthesis

1119-48-8
61445-55-4
Synthesis of N-Nitroso-N-Methyl-4-Aminobutyric Acid from 4-(Methylamino)butyric acid

N-Nitroso-N-Methyl-4-Aminobutyric Acid Preparation Products And Raw materials

Raw materials

Preparation Products

N-Nitroso-N-Methyl-4-Aminobutyric Acid Suppliers

Global( 136)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 9553 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30224 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9539 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12373 58
Alfa Chemistry 		+1-5166625404; Info@alfa-chemistry.com United States 20405 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
Guangzhou Tosun Pharmaceutical Limited 		+86-18124244216 +86-18124244216 info@upharm.cn China 998 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Finetech Industry Limited 		58
CR Corporation Limited 		58
sgtlifesciences pvt ltd 		58
Alfa Chemistry 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Guangzhou Tosun Pharmaceutical Limited 		58

View Lastest Price from N-Nitroso-N-Methyl-4-Aminobutyric Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Nitroso-N-methyl-4-Aminobutyric Acid pictures 2026-07-15 N-Nitroso-N-methyl-4-Aminobutyric Acid
61445-55-4
 $30.00-44.00 99.86% 10g TargetMol Chemicals Inc.
Azilsartan Impurity 102 pictures 2026-03-12 Azilsartan Impurity 102
61445-55-4
 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD

61445-55-4(N-Nitroso-N-Methyl-4-Aminobutyric Acid)Related Search:

4-Aminobutyric acid N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID, METHYL ES N-Nitroso-N-Methyl-4-Aminobutyric Acid 3-carboxypropyl-(2-propenyl)nitrosamine butyl(3-carboxypropyl)nitrosamine
N-NITROSOFOLICACID N-PROPYL-N-(3-CARBOXYPROPYL)NITROSAMINE N-AMYL-N-(3-CARBOXYPROPYL)NITROSAMINE 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid BUTYRICACID,4-(BUTYLNITROSOAMINO)-3-HYDROXY-
N-ETHYL-N-(3-CARBOXYPROPYL)NITROSAMINE N-(3-Carboxypropyl)-N-nitrosourea N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID, METHYL ESTER

1of3

Losartan Impurity 17 N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID 4-(methylnitrosoamino)-butyricaci 4-(n-nitroso-n-methylamino)butyricacid n-methyl-n-(3-carboxypropyl)nitrosamine 4-(N-NITROSOMETHYLAMINO)BUTYRICACID 4-(Methylnitrosoamino)butanoic acid Azilsartan Impurity 102 N-Nitroso-N-methyl-4-aminobutyric Acid (200 μg/mL in Methanol) N-Nitroso-N-Methyl-4-Aminobutyric Acid (Mixture of Isomers) Nitrosoamine MCP Impurity Butanoic acid, 4-(methylnitrosoamino)- 4-[methyl(nitroso)amino]butanoicaci N-nitroso-1-methyl-4-chloro-butyric acid (MBA) Losartan genotoxic impurity N-Nitroso-N-methyl-4-aminobutyric Acid (1mg/1ml) N-Nitroso-N-methyl-4-aminobutyric Acid (2mg/10ml in MeOH) Rosuvastatin Impurity 186 Losartan Impurity 41 N-NITROSO-N-METHYLAMINO BUTYRIC ACID N-Nitroso-N-methyl-3-aminobutyric Acid Nitroso-N-methyl-4-aminobutyric acid (NMBA) 4-(Methylnitrosoamino)butanoic Acid N-nitroso-N-methyl-4-aminobutyric acid, NMBA3,6 N-Nitroso-N-methyl-4-aminobutyric Acid (Mixture of Isomers) (NMBA) 4-(Methylnitrosoamino)butanoic acid-d9 in methanol Losartan Impurity 1(N-Nitroso-N-methyl-4-aminobutyric Acid) N-Nitrosomethylaminobutyric Acid (NMBA) N-Nitroso-N-methyl-4-aminobutyric acid N56-004 Azisartan Impurity 102 N-Nitroso-N-methyl-4-aminobutyric Acid (Standard) NMBA 61445-55-4 Aliphatics Nicotine Derivatives