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TCO-PEG2-amine

CAS No.
2141981-87-3
Chemical Name:
TCO-PEG2-amine
Synonyms
TCO-PEG2-amine;(4E)-TCO-PEG2-amine;Cyclooct-4-en-1-yl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate;Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, 4-cycloocten-1-yl ester
CBNumber:
CB44849681
Molecular Formula:
C15H28N2O4
Molecular Weight:
300.39
MDL Number:
MFCD31811523
MOL File:
2141981-87-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:44:51

TCO-PEG2-amine Properties

Boiling point 448.3±45.0 °C(Predicted)
Density 1.08±0.1 g/cm3(Predicted)
storage temp. 2-8°C, protect from light
solubility Soluble in DMSO, DCM, DMF
form Liquid
pka 11.95±0.46(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

TCO-PEG2-amine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114634 TCO-PEG2-amine ≥97% 2141981-87-3 25mg $189 2026-06-04 Buy
ChemScene CS-0114634 TCO-PEG2-amine ≥97% 2141981-87-3 50mg $321 2026-06-04 Buy
ChemScene CS-0114634 TCO-PEG2-amine ≥97% 2141981-87-3 100mg $545 2026-06-04 Buy
ChemScene CS-0114634 TCO-PEG2-amine ≥97% 2141981-87-3 250mg $980 2026-06-04 Buy
ChemScene CS-0114634 TCO-PEG2-amine ≥97% 2141981-87-3 1g $1800 2026-06-04 Buy
Product number Packaging Price Buy
CS-0114634 25mg $189 Buy
CS-0114634 50mg $321 Buy
CS-0114634 100mg $545 Buy
CS-0114634 250mg $980 Buy
CS-0114634 1g $1800 Buy

TCO-PEG2-amine Chemical Properties, Uses, Production

Description

TCO-PEG2-amine contains a click chemistryTCO moiety and a free amine. This reagent can be used to derivatize activated esters or carboxyl groups through a stable amide bond in the presence of of activators EDC. The hydrophilic PEG linker increases the solubility of compounds in aqueous media.

Uses

TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001

TCO-PEG2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

TCO-PEG2-amine Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 13892832556 2440688701@qq.com China 1978 58
Taizhou Nanfeng Pharmaceutical Research Institute nanfengpharma@126.co 18616377689 nanfengpharma@126.com China 20008 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Shanghai Huici Pharmaceutical Technology Co., LTD 133-31922809 19372841038 lixing@pharmahuici.com China 853 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58

View Latest Price from TCO-PEG2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TCO-PEG2-amine pictures 2025-08-22 TCO-PEG2-amine
2141981-87-3
$57.00 10g TargetMol Chemicals Inc.

TCO-PEG2-amine Spectrum

TCO-PEG2-amine Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, 4-cycloocten-1-yl ester Cyclooct-4-en-1-yl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate (4E)-TCO-PEG2-amine 2141981-87-3