TCO-PEG2-amine
- CAS No.
- 2141981-87-3
- Chemical Name:
- TCO-PEG2-amine
- Synonyms
- TCO-PEG2-amine;(4E)-TCO-PEG2-amine;Cyclooct-4-en-1-yl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate;Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, 4-cycloocten-1-yl ester
- CBNumber:
- CB44849681
- Molecular Formula:
- C15H28N2O4
- Molecular Weight:
- 300.39
- MDL Number:
- MFCD31811523
- MOL File:
- 2141981-87-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
TCO-PEG2-amine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114634 | TCO-PEG2-amine ≥97% | 2141981-87-3 | 25mg | $189 | 2026-06-04 | Buy |
| ChemScene | CS-0114634 | TCO-PEG2-amine ≥97% | 2141981-87-3 | 50mg | $321 | 2026-06-04 | Buy |
| ChemScene | CS-0114634 | TCO-PEG2-amine ≥97% | 2141981-87-3 | 100mg | $545 | 2026-06-04 | Buy |
| ChemScene | CS-0114634 | TCO-PEG2-amine ≥97% | 2141981-87-3 | 250mg | $980 | 2026-06-04 | Buy |
| ChemScene | CS-0114634 | TCO-PEG2-amine ≥97% | 2141981-87-3 | 1g | $1800 | 2026-06-04 | Buy |
TCO-PEG2-amine Chemical Properties, Uses, Production
Description
TCO-PEG2-amine contains a click chemistryTCO moiety and a free amine. This reagent can be used to derivatize activated esters or carboxyl groups through a stable amide bond in the presence of of activators EDC. The hydrophilic PEG linker increases the solubility of compounds in aqueous media.
Uses
TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001
TCO-PEG2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
TCO-PEG2-amine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1978 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | nanfengpharma@126.co 18616377689 | nanfengpharma@126.com | China | 20008 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shanghai Huici Pharmaceutical Technology Co., LTD | 133-31922809 19372841038 | lixing@pharmahuici.com | China | 853 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
View Latest Price from TCO-PEG2-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-08-22 | TCO-PEG2-amine
2141981-87-3
|
$57.00 | 10g | TargetMol Chemicals Inc. |
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- TCO-PEG2-amine
2141981-87-3
- $57.00
- TargetMol Chemicals Inc.





