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5-Nitroquinoline

5-Nitroquinoline Structure
5-Nitroquinoline structure
CAS No.
607-34-1
Chemical Name:
5-Nitroquinoline
Synonyms
AKOS 92273;5-NitroquinoL;5-Nitrochinolin;5-nitro-quinolin;5-NITROQUINOLINE;Quinoline,5-nitro-;5-Nitroquinoline>5-Nitroquinoline,99%;5-NITROQUINOLINE 98+%;5-Nitro-1-azanaphthalene
CBNumber:
CB4484970
Molecular Formula:
C9H6N2O2
Molecular Weight:
174.16
MDL Number:
MFCD00006790
MOL File:
607-34-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 18:42:12
Product description Number Pack Size Price
5-Nitroquinoline 99% N23807 5g $83.8
5-Nitroquinoline >98.0%(GC)(T) N0344 25g $31
5-Nitroquinoline >98.0%(GC)(T) N0344 250g $180
5-Nitroquinoline FN15581 50g $150
5-Nitroquinoline FN15581 100g $240
More product size
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5-Nitroquinoline Properties

Melting point 71-73 °C (lit.)
Boiling point 70-73°C
Density 1.2190 (estimate)
refractive index 1.6820 (rough estimate)
storage temp. Inert atmosphere,Room Temperature
Water Solubility Slightly soluble in water
form powder to crystal
pka 2.80±0.12(Predicted)
color Plates from EtOH (aq)
InChI InChI=1S/C9H6N2O2/c12-11(13)9-5-1-4-8-7(9)3-2-6-10-8/h1-6H
InChIKey NDDZXHOCOKCNBM-UHFFFAOYSA-N
SMILES N1C2C(=C([N+]([O-])=O)C=CC=2)C=CC=1
CAS DataBase Reference 607-34-1(CAS DataBase Reference)
FDA UNII XHP5J23AZ5
NIST Chemistry Reference Quinoline, 5-nitro-(607-34-1)
EPA Substance Registry System 5-Nitroquinoline (607-34-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Warning
Hazard statements  H302+H312+H332-H351
Precautionary statements  P201-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-40-68-36/37/38
Safety Statements  7-22-36-45-36/37/39-26
WGK Germany  3
RTECS  VC1850000
Hazard Note  Irritant
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Carc. 2
Toxicity mmo-sat 10 mg/plate MUREAV 92,29,82

5-Nitroquinoline price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N23807 5-Nitroquinoline 99% 607-34-1 5g $83.8 2023-06-20 Buy
TCI Chemical N0344 5-Nitroquinoline >98.0%(GC)(T) 607-34-1 25g $31 2026-04-30 Buy
TCI Chemical N0344 5-Nitroquinoline >98.0%(GC)(T) 607-34-1 250g $180 2026-04-30 Buy
Biosynth FN15581 5-Nitroquinoline 607-34-1 50g $150 2026-06-04 Buy
Biosynth FN15581 5-Nitroquinoline 607-34-1 100g $240 2026-06-04 Buy
Product number Packaging Price Buy
N23807 5g $83.8 Buy
N0344 25g $31 Buy
N0344 250g $180 Buy
FN15581 50g $150 Buy
FN15581 100g $240 Buy

5-Nitroquinoline Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx. Seealso other nitroquinoline entries.

Synthesis

Quinoline

91-22-5

8-Nitroquinoline

607-35-2

5-Nitroquinoline

607-34-1

General procedure for the synthesis of 8-nitroquinoline and 5-nitroquinoline from quinoline: Pure sulfuric acid (H2SO4) was slowly added to 1 equivalent of quinoline at 0 °C. Subsequently, 3 equivalents of 65% nitric acid (HNO3) were added dropwise and the reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the mixture was poured sequentially into ice water, neutralized with sodium carbonate (Na2CO3) to pH neutral, and then extracted twice with dichloromethane (DCM). The organic layers were combined, washed with water, dried over anhydrous sodium sulfate (Na2SO4) and finally the solvent was evaporated under vacuum. 8-Nitroquinoline (compound 35) was obtained as a light yellow solid in 34% yield; melting point 90 °C, literature value: 89-90 °C [43].1H NMR (200 MHz, CDCl3) δ: 7.53-7.66 (m, 2H), 8.04 (d, J = 8.0 Hz, 2H), 8.27 (dd, J = 1.6 and 8.4 Hz, 1H). 9.70 (dd, J = 1.7 and 4.2 Hz, 1H). 13C NMR (50 MHz, CDCl3) δ: 122.8 (CH), 123.8 (CH), 125.3 (CH), 129.0 (C), 132.0 (CH), 136.1 (CH), 139.5 (C), 148.2 (C), 152.6 (CH ). Recrystallization by isopropanol afforded 5-nitroquinoline (compound 36) as a light yellow solid in 38% yield; melting point 71 °C, literature value: 71-72 °C [41].1H NMR (200 MHz, CDCl3) δ: 7.61-7.68 (m, 1H), 7.76-7.85 (m, 1H), 8.36-8.45 (m, 2H). 8.98-9.04 (m, 2H).13C NMR (50MHz, CDCl3) δ: 121.2 (C), 123.9 (CH), 124.6 (CH), 127.5 (CH), 131.9 (CH), 136.6 (CH), 145.5 (C), 148.2 (C), 151.6 (C).

Purification Methods

Crystallise 5-nitroquinoline from pentane, then from *benzene. The hydrochloride has m 224o and the picrate has m 206o, 214o(from MeOH). [Beilstein 20 H 371, 20 II 235, 20 III/IV 3397.]

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 75 - 86
[2] European Journal of Medicinal Chemistry, 2018, vol. 155, p. 135 - 152
[3] Journal of the Chemical Society, 1892, vol. 61, p. 788
[4] Chemische Berichte, 1885, vol. 18, p. 1243
[5] Journal fuer Praktische Chemie (Leipzig), 1896, vol. <2> 53, p. 392

5-Nitroquinoline Preparation Products And Raw materials

Raw materials

7-NITRO-QUINOLINE Sodium carbonate 3-Nitroaniline Quinoline Glycerol

Preparation Products

5-Hydroxyquinoline 2-Chloro-5-nitroquinoline 5-Amino-8-hydroxyquinoline

5-Nitroquinoline Suppliers

Global( 269)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 874 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63645 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
Fuxin Pharmaceutical 		+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
Nantong Haigine Pharma Technology Co., Ltd 		0086-513-86266699 CHINA 156 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17339 58
Shanghai Rlavie Technology Co ltd 		+86-021-67759270 +86-17717059219 sales@rlavie.com China 1030 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Nanjing Finetech Chemical Co., Ltd. 		55
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Fuxin Pharmaceutical 		58
Nantong Haigine Pharma Technology Co., Ltd 		58
SIMAGCHEM CORP 		58
Shanghai Rlavie Technology Co ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58

View Lastest Price from 5-Nitroquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Nitroquinoline pictures 2026-07-14 5-Nitroquinoline
607-34-1
 1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
5-Nitroquinoline pictures 2026-07-02 5-Nitroquinoline
607-34-1
 $3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
5-Nitroquinoline pictures 2025-11-18 5-Nitroquinoline
607-34-1
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
  • 5-Nitroquinoline pictures
  • 5-Nitroquinoline
    607-34-1
  • $3.00-9.00
  • 99%
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

5-Nitroquinoline Spectrum

5-Nitroquinoline(607-34-1)MS5-Nitroquinoline(607-34-1)1HNMR5-Nitroquinoline(607-34-1)13CNMR5-Nitroquinoline(607-34-1)IR15-Nitroquinoline(607-34-1)IR25-Nitroquinoline(607-34-1)Raman

607-34-1(5-Nitroquinoline)Related Search:

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quinolinium hydrogen sulphate Isoquinoline Quinclorac 6-METHYL-5-NITROQUINOLINE 5-nitrobenzofuran
5-NITRO-1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID 5-Nitro-1,10-phenanthroline 8-chloro-5-nitro-quinoline 6-BROMO-5-NITROQUINOLINE 7-METHYL-8-NITROQUINOLINE
5-Amino-6-nitroquinoline 7-Nitro-1,2,3,4-tetrahydroquinoline Nitroxoline

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