AROTINOLOL
- CAS No.
- 68377-92-4
- Chemical Name:
- AROTINOLOL
- Synonyms
- Arotinolo;Arolol;Arot-API;Arottnolol;AROTINOLOL;NSC 317940;Arotinolol (Almarl);Arotinolol free base;AROTINOLOL USP/EP/BP;Arotinolol Intermediate
- CBNumber:
- CB4486237
- Molecular Formula:
- C15H21N3O2S3
- Molecular Weight:
- 371.54
- MDL Number:
- MFCD00865895
- MOL File:
- 68377-92-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 148-149° |
|---|---|
| Boiling point | 599.8±60.0 °C(Predicted) |
| Density | 1.35 |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 13.71±0.20(Predicted) |
| form | Solid |
| color | Off-White to Pale Yellow |
| FDA UNII | 394E3P3B99 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
AROTINOLOL price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-A771500-1G | Arotinolol | 68377-92-4 | 1g | $2062 | 2026-06-03 | Buy |
| TRC | TRC-A771500-100MG | Arotinolol | 68377-92-4 | 100mg | $282 | 2026-06-03 | Buy |
| ChemScene | CS-0102757 | Arotinolol 99.93% | 68377-92-4 | 5mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0102757 | Arotinolol 99.93% | 68377-92-4 | 10mg | $81 | 2026-06-04 | Buy |
| ChemScene | CS-0102757 | Arotinolol 99.93% | 68377-92-4 | 25mg | $141 | 2026-06-04 | Buy |
AROTINOLOL Chemical Properties, Uses, Production
Originator
Arotinolol,ZYF Pharm
Uses
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.
Definition
ChEBI: Arotinolol is a member of thiophenes and an aromatic amide.
Manufacturing Process
To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in
20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol,
12.64 g in 20 ml of methanol was added, while the
temperature was maintained at 20°C.
The reaction solution was stirred at room temperature for 4 h, and then
condensed to a half volume in vacuo. The residual solution, added with 100 ml
of water, was extracted with chloroform. The chloroform extract was washed
with water, dried over anhydrous magnesium sulfate and evaporated in vacuo
to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-
thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec.,
recrystallized from methanol/water).
In practice it is usually used as hydrochloride.
Therapeutic Function
Beta-adrenergic blocker
AROTINOLOL Preparation Products And Raw materials
AROTINOLOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai joygo pharmacetical tech., Co., Ltd. | 13621615409 | sale1@joygooo.com | China | 108 | 50 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9506 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from AROTINOLOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-16 | Arotinolol Impurity
68377-92-4
|
10mg | 98 | 10000000 | Moxin Chemicals | ||
 |
2024-10-22 | AROTINOLOL
68377-92-4
|
$1.00 | 1g | 85.0-99.8% | 20ton | Career Henan Chemica Co | |
 |
2023-06-26 | Arotinolol
68377-92-4
|
$200.00 | 1kg | 99% | 1000kg/Month | Hebei Mingeng Biotechnology Co., Ltd |
-
- Arotinolol Impurity
68377-92-4
- 98
- Moxin Chemicals
-
- AROTINOLOL
68377-92-4
- $1.00
- 85.0-99.8%
- Career Henan Chemica Co
-
- Arotinolol
68377-92-4
- $200.00
- 99%
- Hebei Mingeng Biotechnology Co., Ltd
