MK-0493
- CAS No.
- 455957-71-8
- Chemical Name:
- MK-0493
- Synonyms
- MK-0493 HCl;MK0493 HCl,MK 0493 HCl
- CBNumber:
- CB44920737
- Molecular Formula:
- C30H39Cl2F2N3O2
- Molecular Weight:
- 582.56
- MDL Number:
- MOL File:
- 455957-71-8.mol
- MSDS File:
- SDS
| form | Solid |
|---|---|
| FDA UNII | 48BVK2JYXI |
MK-0493 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0109986 | MK-0493 hydrochloride 98.76% | 455957-71-8 | 5mg | $466 | 2026-06-04 | Buy |
| ChemScene | CS-0109986 | MK-0493 hydrochloride 98.76% | 455957-71-8 | 10mg | $747 | 2026-06-04 | Buy |
| aablocks | AA024C55 | MK-0493 >98% | 455957-71-8 | 5mg | $513 | 2026-06-01 | Buy |
| aablocks | AA024C55 | MK-0493 >98% | 455957-71-8 | 10mg | $802 | 2026-06-01 | Buy |
| Arctom | HY-118930A | MK-0493 hydrochloride 98.76% | 455957-71-8 | 5mg | $409 | 2026-05-26 | Buy |
MK-0493 Chemical Properties, Uses, Production
Uses
MK-0493 hydrochloride is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R), demonstrating significant reductions in energy intake[1].
References
[1] Krishna R, etal. Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy. Clin Pharmacol Ther. 2009 Dec;86(6):659-66. DOI:10.1038/clpt.2009.167
[2] Sezen SF, et al. Intracavernosal pressure monitoring in mice: responses to electrical stimulation of the cavernous nerve and to intracavernosal drug administration. J Androl. 2000 Mar-Apr;21(2):311-5. PMID:10714826
[3] Hong Q, et al. Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2330-4. DOI:10.1016/j.bmcl.2011.02.090
MK-0493 Preparation Products And Raw materials
Raw materials
Preparation Products
MK-0493 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
