PROTAC MDM2 Degrader-1
- CAS No.
- 2249944-98-5
- Chemical Name:
- PROTAC MDM2 Degrader-1
- Synonyms
- PROTAC MDM2 Degrader-1;1-Piperazineacetamide, N,N'-[oxybis(2,1-ethanediyloxy-3,1-propanediyl)]bis[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-, rel-
- CBNumber:
- CB45821235
- Molecular Formula:
- C74H84Cl4N10O13
- Molecular Weight:
- 1463.33
- MDL Number:
- MFCD32197288
- MOL File:
- 2249944-98-5.mol
- MSDS File:
- SDS
PROTAC MDM2 Degrader-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0100638 | PROTAC MDM2 Degrader-1 98.11% | 2249944-98-5 | 1mg | $609 | 2026-06-04 | Buy |
| ChemScene | CS-0100638 | PROTAC MDM2 Degrader-1 98.11% | 2249944-98-5 | 5mg | $1219 | 2026-06-04 | Buy |
| ChemScene | CS-0100638 | PROTAC MDM2 Degrader-1 98.11% | 2249944-98-5 | 10mg | $1950 | 2026-06-04 | Buy |
| ChemScene | CS-0100638 | PROTAC MDM2 Degrader-1 98.11% | 2249944-98-5 | 25mg | $3575 | 2026-06-04 | Buy |
| aablocks | AA01THZH | PROTAC MDM2 Degrader-1 >98% | 2249944-98-5 | 1mg | $660 | 2026-05-31 | Buy |
PROTAC MDM2 Degrader-1 Chemical Properties, Uses, Production
Uses
PROTAC MDM2 Degrader-1 (Compound 15a) is a MDM2 PROTAC degrader. The structures of both Linker ends of PROTAC MDM2 Degrader-1 are MDM2 ligands. PROTAC MDM2 Degrader-1 can not only block the binding of p53-MDM2, but also degrade the target MDM2 protein by utilizing the function of the E3 ligase of MDM2 itself, thus exerting an anti-tumor effect. (Pink: MDM2 ligand 2 (HY-128836); Black: Linker (HY-128844); Blue: E3 ligase Ligand 15 (HY-128836))[1]
IC 50
MDM2
References
[1] Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.
PROTAC MDM2 Degrader-1 Preparation Products And Raw materials
Raw materials
Preparation Products
PROTAC MDM2 Degrader-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1644 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 9067 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| 19011298796 19011298796 | 17816380947@139.com | China | 474 | 58 |
