Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Structure
1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL structure
CAS No.
59767-24-7
Chemical Name:
1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL
Synonyms
Clemastine EP Impurity C;Chloramine T EP impurity C;CleMastine FuMarate IMpurity C;Clemastine Fumarate EP Impurity C;1-(p-Chlorophenyl)-1-phenylethanol;(RS)-1-(4-Chlorophenyl)-1-phenyleth;Clemastine Impurity 3(EP Impurity C);1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL;1-(4-chlorophenyl)-1-phenylethan-1-ol;(RS)-1-(4-Chlorophenyl)-1-phenylethanol
CBNumber:
CB4587596
Molecular Formula:
C14H13ClO
Molecular Weight:
232.71
MDL Number:
MFCD09743490
MOL File:
59767-24-7.mol
MSDS File:
SDS
Last updated:2026-07-16 18:07:46
Product description Number Pack Size Price
1-(4-Chlorophenyl)-1-phenylethanol British Pharmacopoeia (BP) Reference Standard BP955 25MG $251
1-(4-Chlorophenyl)-1-phenylethanol TRC-C380475-25MG 25mg $158
1-(4-Chlorophenyl)-1-phenylethanol TRC-C380475-250MG 250mg $233
1-(4-Chlorophenyl)-1-phenylethanol TRC-C380475-1G 1g $540
1-(4-Chlorophenyl)-1-phenylethanol JCA76724 5g $900
Request For Quotation

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Properties

Boiling point 358℃
Density 1.189
Flash point 170℃
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 13.41±0.29(Predicted)
form Oil
color Colourless to Light Yellow
Major Application pharmaceutical
pharmaceutical small molecule
InChI 1S/C14H13ClO/c1-14(16,11-5-3-2-4-6-11)12-7-9-13(15)10-8-12/h2-10,16H,1H3
InChIKey MHJLXHJZQCHSIT-UHFFFAOYSA-N
SMILES Clc1ccc(cc1)C(O)(C)c2ccccc2
FDA UNII 6149LO684B
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P301+P312+P330-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
REACH Registrations Active

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich BP955 1-(4-Chlorophenyl)-1-phenylethanol British Pharmacopoeia (BP) Reference Standard 59767-24-7 25MG $251 2026-04-30 Buy
TRC TRC-C380475-25MG 1-(4-Chlorophenyl)-1-phenylethanol 59767-24-7 25mg $158 2026-06-03 Buy
TRC TRC-C380475-250MG 1-(4-Chlorophenyl)-1-phenylethanol 59767-24-7 250mg $233 2026-06-03 Buy
TRC TRC-C380475-1G 1-(4-Chlorophenyl)-1-phenylethanol 59767-24-7 1g $540 2026-06-03 Buy
Biosynth JCA76724 1-(4-Chlorophenyl)-1-phenylethanol 59767-24-7 5g $900 2026-06-04 Buy
Product number Packaging Price Buy
BP955 25MG $251 Buy
TRC-C380475-25MG 25mg $158 Buy
TRC-C380475-250MG 250mg $233 Buy
TRC-C380475-1G 1g $540 Buy
JCA76724 5g $900 Buy

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Chemical Properties,Uses,Production

Uses

1-(4-Chlorophenyl)-1-phenylethanol (Clemastine EP Impurity C) is used in the synthetic preparation of rhodium-catalyzed arylation of nitriles, ketones and imines with tetrafluoroborate or arylboronic acids

Synthesis

Bromobenzene

108-86-1

4'-Chloroacetophenone

99-91-2

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL

59767-24-7

1. A solution was prepared by dissolving bromobenzene (20.31 g, 129.35 mmol) in anhydrous tetrahydrofuran (50 mL) under nitrogen protection. 2. The above solution was added slowly and dropwise to a reaction flask containing magnesium shavings (3.88 g, 159.61 mmol), dry tetrahydrofuran (50 mL) and iodine crystals. 3. After heating and refluxing for about 2 hours, the resulting solution of Grignard reagent was cooled to about 0°C. 4. A tetrahydrofuran solution (100 mL) of 1-(4-chlorophenyl)ethanone (10.0 g, 64.69 mmol) was slowly added dropwise to the cooled Grignard reagent solution described above at 0°C. 5. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for about 18 hours. 6. Upon completion of the reaction, the mixture was cooled to about 0°C and the reaction was quenched by slow addition of saturated ammonium chloride solution. 7. The organic phase was collected after standard extraction using ethyl acetate. 8. The crude product was purified by silica gel column chromatography with petroleum ether solution of 5% ethyl acetate as eluent to afford the title compound 1-(4-chlorophenyl)-1-phenylethanol as an oil (3.80 g, 25% yield). 9. The product was characterized as follows: 1H NMR (400 MHz, CDCl3) δ 1.94 (s, 3H), 2.17 (s, 1H, exchangeable with D2O), 7.23-7.42 (m, 9H). IR (membrane) υ 3414, 3061, 2978, 2927, 2859, 1597, 1489, 1449, 1394 cm-1; MS 215, 217 [(s, 1H, exchangeable with D2O)]. MS 215, 217 [(M+1)-H2O, (M+3)-H2O].

References

[1] Patent: US2009/203763, 2009, A1. Location in patent: Page/Page column 35

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Preparation Products And Raw materials

Raw materials

Bromobenzene 4'-Chloroacetophenone Phenylmagnesium bromide Water Magnesium
Ammonium chloride Tetrahydrofuran

1of2

Preparation Products

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21533 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569262 +86-15003564040 1056@dideu.com China 3970 58
Hefei Hangang Pharmaceutical Technology Co., Ltd. 		+8618062405514 ada@ipurechemical.com China 10224 58
Chemsigma International Co., Ltd. 		+86-2558742998 +86-19951791336 info@chemsigma.com China 1824 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +8619957148339 market18@leapchem.com China 24569 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hefei Hangang Pharmaceutical Technology Co., Ltd. 		58
Chemsigma International Co., Ltd. 		58
BOC Sciences 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
GIHI CHEMICALS CO.,LIMITED 		58

View Lastest Price from 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL pictures 2026-08-20 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL
59767-24-7
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL pictures 2026-07-16 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL
59767-24-7
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL pictures 2025-08-20 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL
59767-24-7
 1kg 99.99% 20 tons Chongqing Soarwin Technology Co., Ltd

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL Spectrum

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL(59767-24-7)1HNMR

59767-24-7(1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL)Related Search:

Dicofol CHLOROPROPYLATE 3,4,5,6-TETRACHLOROFLUORESCEIN CHLOROBENZILATE Acid Red 92
2',4',5',7'-TETRABROMO-3,4,5,6-TETRACHLOROFLUORESCEIN 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL ROSE BENGAL 4,4',4''-TRICHLOROTRITYL ALCOHOL FLUORESCEIN CHLORIDE
ROSE BENGAL Clemastine fumarate Fenarimol ROSE BENGAL LACTONE o,p'-dicofol
1,1-BIS(4-CHLOROPHENYL)-2-[(2-CHLOROPHENYL)SULFONYL]-1-ETHANOL 1,1-BIS(4-CHLOROPHENYL)-2-[(4-CHLOROPHENYL)SULFONYL]-1-ETHANOL 1,1-BIS(4-CHLOROPHENYL)-2-[(4-CHLOROPHENYL)SULFANYL]-1-ETHANOL

1of4

1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL 1-(p-Chlorophenyl)-1-phenylethanol 4-Chloro-α-methyl-α-phenylbenzenemethanol α-Methyl-α-phenyl-4-chlorobenzenemethanol CleMastine FuMarate IMpurity C Clemastine Impurity 3(EP Impurity C) Clemastine EP Impurity C Clemastine Fumarate EP Impurity C (RS)-1-(4-Chlorophenyl)-1-phenyleth Benzenemethanol, 4-chloro-α-methyl-α-phenyl- 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL ISO 9001：2015 REACH 59767-24-7 1 -(4-CHLOROPHENYL)-1 -PHENYLETHANOL (RS)-1-(4-Chlorophenyl)-1-phenylethanol 1-(4-Chlorophenyl)-1-phenylethanol (Clemastine Impurity) Chloramine T EP impurity C 1-(4-chlorophenyl)-1-phenylethan-1-ol 59767-24-7 C14H13CO