pNPS-DHA
- CAS No.
- 2454246-25-2
- Chemical Name:
- pNPS-DHA
- Synonyms
- pNPS-DHA;pNPS DHA,pNPSDHA;4,7,10,13,16,19-Docosahexaenamide, N-[(4-nitrophenyl)sulfonyl]-, (4Z,7Z,10Z,13Z,16Z,19Z)-;(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(4-nitrophenyl)sulfonyl]docosa-4,7,10,13,16,19-docosahexaenamide
- CBNumber:
- CB46197836
- Molecular Formula:
- C28H36N2O5S
- Molecular Weight:
- 512.66
- MDL Number:
- MOL File:
- 2454246-25-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
pNPS-DHA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29507 | pNPS-DHA ≥98% | 2454246-25-2 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 29507 | pNPS-DHA ≥98% | 2454246-25-2 | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 29507 | pNPS-DHA ≥98% | 2454246-25-2 | 10mg | $186 | 2026-04-30 | Buy |
| Cayman Chemical | 29507 | pNPS-DHA ≥98% | 2454246-25-2 | 25mg | $420 | 2026-04-30 | Buy |
| Biosynth | EYD24625 | (4Z,7Z,10Z,13Z,16Z,19Z)-N-[(4-Nitrophenyl)sulfonyl]docosa-4,7,10,13,16,19-docosahexaenamide | 2454246-25-2 | 25mg | $985.25 | 2026-06-04 | Buy |
pNPS-DHA Chemical Properties, Uses, Production
Uses
pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM[1].
Biological Activity
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 μM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.
References
1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
pNPS-DHA Preparation Products And Raw materials
Raw materials
Preparation Products
pNPS-DHA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
