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5-Chloro-1-pentyne

5-Chloro-1-pentyne structure

CAS No.: 14267-92-6

Chemical Name:: 5-Chloro-1-pentyne

Synonyms: 5-chloropent-1-yne;4-PENTYNYL CHLORIDE;EOS-60333;Chloro-1-pent;5-Chloropentyne;5-chloro-1-pentyn;5-chloro -1-pentyl;1-Chloro-4-pentyne;5-CHLORO-1-PENTYNE;1-Pentyne,5-chloro-

CBNumber:: CB4709428

Molecular Formula:: C5H7Cl

Molecular Weight:: 102.56

MDL Number:: MFCD00001014

MOL File:: 14267-92-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:29:54

Product description	Number	Pack Size	Price
5-Chloro-1-pentyne 98%	244376	5g	$58.6
5-Chloro-1-pentyne 98%	244376	25g	$143
5-Chloro-1-pentyne >96.0%(GC)	C1522	5mL	$33
5-Chloro-1-pentyne >96.0%(GC)	C1522	25mL	$113
5-Chloropent-1-yne	436237	2.5g	$403
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5-Chloro-1-pentyne Properties

Melting point	-61°C (estimate)
Boiling point	67-69 °C145 mm Hg(lit.)
Density	0.968 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point	60 °F
storage temp.	2-8°C
solubility	Chloroform, Methanol (Slightly)
form	Liquid
Specific Gravity	0.968
color	Clear colorless to light brown
Water Solubility	Not miscible in water.
BRN	1736710
InChI	1S/C5H7Cl/c1-2-3-4-5-6/h1H,3-5H2
InChIKey	UXFIKVWAAMKFQE-UHFFFAOYSA-N
SMILES	ClCCCC#C
CAS DataBase Reference	14267-92-6(CAS DataBase Reference)
NIST Chemistry Reference	5-Chloro-1-pentyne(14267-92-6)
EPA Substance Registry System	1-Pentyne, 5-chloro- (14267-92-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H315

Precautionary statements

P210-P302+P352

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

F,Xi

Risk Statements

11-38-36/37/38

Safety Statements

23-24/25-16

RIDADR

UN 1993 3/PG 2

WGK Germany

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

PackingGroup

HS Code

29032900

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 2
Skin Irrit. 2

Limited Quantities

1.0 L (0.3 gallon) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	3
2		0

5-Chloro-1-pentyne price More Price(82)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	244376	5-Chloro-1-pentyne 98%	14267-92-6	5g	$58.6	2026-04-30	Buy
Sigma-Aldrich	244376	5-Chloro-1-pentyne 98%	14267-92-6	25g	$143	2026-04-30	Buy
TCI Chemical	C1522	5-Chloro-1-pentyne >96.0%(GC)	14267-92-6	5mL	$33	2026-04-30	Buy
TCI Chemical	C1522	5-Chloro-1-pentyne >96.0%(GC)	14267-92-6	25mL	$113	2026-04-30	Buy
Usbiological	436237	5-Chloropent-1-yne	14267-92-6	2.5g	$403	2026-06-03	Buy

Product number	Packaging	Price	Buy
244376	5g	$58.6	Buy
244376	25g	$143	Buy
C1522	5mL	$33	Buy
C1522	25mL	$113	Buy
436237	2.5g	$403	Buy

5-Chloro-1-pentyne Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS TO LIGHT BROWN LIQUID

Uses

5-Chloro-1-pentyne is used with α-diazoesters in a copper-catalyzed synthesis of pyrazoles. It is also used in the synthesis of 5-chloro-2-trimethylstannyl-1-pentene by reacting with Me3SnCu.Me2S.

Uses

5-Chloro-1-pentyne was used in the synthesis of 5-chloro-2-trimethylstannyl-1-pentene by reacting with Me₃SnCu.Me₂S. It was also used with α-diazoesters in a copper-catalyzed synthesis of pyrazoles.

Synthesis

5390-04-5

14267-92-6

General procedure for the synthesis of 5-chloro-1-pentyne from 4-pentyn-1-ol: The reaction system was first cooled to 15 °C, followed by the addition of 540 g (6.42 mol) of 4-pentyn-1-ol and 682 g (6.74 mol) of triethylamine to 975 g (7.70 mol) of o-chlorotoluene with stirring and mixing. 772 g (6.74 mol) of methanesulfonyl chloride was slowly added dropwise over a period of 2 h. The internal temperature of the reaction was controlled to be maintained between 15-20 °C. After the dropwise addition was completed, stirring was continued for 30 minutes to ensure that the reaction was complete and the reaction mixture was obtained. Subsequently, the reaction mixture was heated to 90 °C and stirred continuously at this temperature for 2 hours. After completion of the reaction, the mixture was cooled to room temperature. Triethylamine and methanesulfonyl chloride derived by-products were removed from the reaction mixture by washing with water. The organic phase was separated and dried with magnesium sulfate to give 1651 g of organic phase containing 581 g (5.66 mol) of 5-chloro-1-pentynylene in 88.2% reaction yield. The organic phase was mainly composed of o-chlorotoluene (boiling point: 159 °C) and 5-chloro-1-pentyne (boiling point: 113 °C). Finally, the organic phase was purified by decompression distillation to give 584.2 g of 5-chloro-1-pentynyne with 98.2% purity, and the yield of the distillation process was 98.4%.

References

[1] Patent: JP2016/94366, 2016, A. Location in patent: Paragraph 0039; 0040
[2] Organic Letters, 2014, vol. 16, # 6, p. 1720 - 1723
[3] Journal of the Chemical Society, 1950, p. 3650,3655

5-Chloro-1-pentyne synthesis

Synthesis of 5-Chloro-1-pentyne from 4-Pentyn-1-ol

5-Chloro-1-pentyne Preparation Products And Raw materials

Raw materials

4-Pentyn-1-ol

Preparation Products

1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE 6-Chlorohexanoic acid Morpholine, 4-(4-pentyn-1-yl)-

5-Chloro-1-pentyne Suppliers

Global( 275)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9996	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9539	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Shaanxi Dideu Medichem Co. Ltd	58
Alfa Chemistry	58
Finetech Industry Limited	58

View Lastest Price from 5-Chloro-1-pentyne manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-25	5-Chloro-1-pentyne 14267-92-6	$1.00-100.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2025-04-04	5-Chloro-1-pentyne 14267-92-6		25KG	97%	1ton	Henan Aochuang Chemical Co.,Ltd.
2020-01-08	5-Chloro-1-pentyne 14267-92-6	$3.00	1KG	98%	200KG	Career Henan Chemical Co

5-Chloro-1-pentyne
14267-92-6
$1.00-100.00
99%
Henan Fengda Chemical Co., Ltd

5-Chloro-1-pentyne
14267-92-6
$0.00
97%
Henan Aochuang Chemical Co.,Ltd.

5-Chloro-1-pentyne
14267-92-6
$3.00
98%
Career Henan Chemical Co

5-Chloro-1-pentyne Spectrum

5-Chloro-1-pentyne(14267-92-6)¹HNMR 5-Chloro-1-pentyne(14267-92-6)IR1

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