Exenatide acetate
- CAS No.
- 141732-76-5
- Chemical Name:
- Exenatide acetate
- Synonyms
- Exenatide;AI315415;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;exendin-4, PC-DAC;EXENATIDE ACETATE;Exennatide Acetate
- CBNumber:
- CB4789871
- Molecular Formula:
- C186H286N50O62S
- Molecular Weight:
- 4244.60796
- MDL Number:
- MFCD08704781
- MOL File:
- 141732-76-5.mol
- MSDS File:
- SDS
| Melting point | >209°C (dec.) |
|---|---|
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | Acetonitrile (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Sequence | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| CAS DataBase Reference | 141732-76-5(CAS DataBase Reference) |
| FDA UNII | 9P1872D4OL |
| NCI Drug Dictionary | exenatide |
| ATC code | A10BJ01 |
Exenatide acetate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FE23212 | Exenatide acetate | 141732-76-5 | 0.025g | $459.61 | 2026-06-04 | Buy |
| Biosynth | FE23212 | Exenatide acetate | 141732-76-5 | 0.05g | $778 | 2026-06-04 | Buy |
| Biosynth | FE23212 | Exenatide acetate | 141732-76-5 | 0.1g | $1103.08 | 2026-06-04 | Buy |
| aablocks | AA0039QE | Exenatide acetate | 141732-76-5 | 1mg | $66 | 2026-05-28 | Buy |
| aablocks | AA0039QE | Exenatide acetate | 141732-76-5 | 2mg | $87 | 2026-05-28 | Buy |
Exenatide acetate Chemical Properties, Uses, Production
Chemical Properties
Exenatide acetate is White Solid
Uses
Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.
Uses
A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Clinical Use
39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.
Drug interactions
Potentially hazardous interactions with other drugs Anticoagulants: possibly enhances anticoagulant effect of warfarin. Other nephrotoxins: avoid concomitant use.
Metabolism
Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.
Description
Exenatide is a single, non-glycosylated, peptide containing 39 amino acids and having a molecular mass of 4186.6 Dalton. Exenatide has the empirical formula C184H282N50O60S.
Background
Exenatide Derived from the saliva of the gila monster, is a 39 amino acid peptide that mimics the GLP-1 incretin, an insulin secretagogue with glucoregulatory effects. Typical responses to exenatide include improvements in the initial rapid release of endogenous insulin, suppression of glucagon release by the pancreas, regulation of gastric empyting, and reduced appetite - all of which function to lower blood glucose. Exenatide is self-regulating in that it lowers blood sugar when levels are elevated but does not continue to lower blood sugar when levels return to normal, unlike with sulfonylureas or insulins.
Exenatide acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shaoxing Junyu Biotechnology Co., LTD | 0571-0571-88211921 19105816207 | sales4@gotopbio.com | China | 5135 | 58 |
| Chinese Peptide Company | 0571-86737118-8680 15988144796 | sales@chinesepeptide.com | China | 10 | 58 |
| bociny | 18939812306 | sales@bociny.com | China | 207 | 58 |
| Shenzhen Zhaoke Biotechnology Co., Ltd | 18271904430 | 1070737105@qq.com | China | 149 | 58 |
| Shanghai Fine Biotech Co.，Ltd | 18221172427; 18221172427 | sale@fine-biotech.com | China | 227 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 17357109671 | sales3@gotopbio.com | China | 2988 | 58 |
| SU ZHOU MOTIF BIOTECH CO.,LTD | 18151592215 18516107567 | info@motifbiotech.com | China | 998 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Hangzhou Zyter Biological & Chemical Technology Co., Ltd. | 18858184290; | sales@zyterpharm.com | China | 47 | 49 |
Related articles
- Exenatide Acetate: A Multifaceted Antidiabetic with Established Efficacy and Evolving Formulations
- Exenatide is a unique agent which can effectively control blood glucose levels in type 2 diabetes mellitus without producing d....
- Apr 14,2025
View Latest Price from Exenatide acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Exenatide acetate
141732-76-5
|
$1.00 | 1g | 99% | 100kg | RongNa Biotechnology Co.,Ltd | |
 |
2026-09-16 | Exenatide acetate
141732-76-5
|
1g | 98%min | 1kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-15 | Exenatide Acetate
141732-76-5
|
$5.00 | 1Box | 99.99% | 20000 boxes | Hebei Jiafan Trading Company Limited |
-
- Exenatide acetate
141732-76-5
- $1.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Exenatide acetate
141732-76-5
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Exenatide Acetate
141732-76-5
- $5.00
- 99.99%
- Hebei Jiafan Trading Company Limited
