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ChemicalBook >> CAS DataBase List >>2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol Structure
2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol structure
CAS No.
496062-16-9
Chemical Name:
2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol
Synonyms
4-Thiazoleethanol,2-bromo-5-methyl-;2-(2-bromo-5-methylthiazol-4-yl)ethanol;2-BroMo-4-(2-hydroxyethyl)-5-Methylthiazole;2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol
CBNumber:
CB4803768
Molecular Formula:
C6H8BrNOS
Molecular Weight:
222.1
MDL Number:
MFCD09038181
MOL File:
496062-16-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:59
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2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth WUA06216 2-Bromo-4-(2-hydroxyethyl)-5-methylthiazole 496062-16-9 1g $649 2026-06-05 Buy
Biosynth WUA06216 2-Bromo-4-(2-hydroxyethyl)-5-methylthiazole 496062-16-9 2g $908.6 2026-06-05 Buy
Biosynth WUA06216 2-Bromo-4-(2-hydroxyethyl)-5-methylthiazole 496062-16-9 5g $1298 2026-06-05 Buy
Biosynth WUA06216 2-Bromo-4-(2-hydroxyethyl)-5-methylthiazole 496062-16-9 10g $2076.8 2026-06-05 Buy
Activate Scientific AS27914 2-Bromo-4-(2-hydroxyethyl)-5-methylthiazole 95% 496062-16-9 1g $226 2026-06-04 Buy
Product number Packaging Price Buy
WUA06216 1g $649 Buy
WUA06216 2g $908.6 Buy
WUA06216 5g $1298 Buy
WUA06216 10g $2076.8 Buy
AS27914 1g $226 Buy

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol Chemical Properties, Uses, Production

Synthesis

4-Thiazoleaceticacid,2-bromo-5-methyl-,methylester(9CI)

496062-15-8

2-(2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ETHANOL

496062-16-9

Example 173 Synthesis of 2-(2-bromo-5-methyl-1,3-thiazol-4-yl)ethanol To a solution of methyl 2-(2-bromo-5-methylthiazol-4-yl)acetate (3.80 g, 15.2 mmol) prepared in Example 172 in dichloromethane (100 mL) was slowly added diisobutylaluminum hydride (DIBAL-H, 33.4 mL, 33.4 mmol, 1.0 M toluene solution) at -78°C. After 15 min of reaction, the reaction system was slowly warmed to 0 °C and stirring was continued for 90 min. Subsequently, 2N aqueous hydrochloric acid solution (50 mL) was added dropwise to quench the excess DIBAL-H. The organic phase was separated and the aqueous phase was extracted with dichloromethane (2 x 200 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Purification of the residue by rapid column chromatography on silica gel (eluent ratio 5:2 hexane/ethyl acetate) afforded the target product 2-(2-bromo-5-methyl-1,3-thiazol-4-yl)ethanol (2.5 g, 74% yield) as a yellow oil, which solidified on standing. Product characterization data: Molecular formula: C6H8BrNOS LC-MS: retention time 1.38 min, [M+H]+ m/z 221.0 1H NMR (CDCl3): δ 2.31 (s, 3H), 2.82 (t, 2H), 2.90-3.00 (wide s, 1H), 3.89 (t, 2H).

References

[1] Patent: US2003/216391, 2003, A1
[2] Patent: US2018/153859, 2018, A1. Location in patent: Paragraph 0552; 0553
[3] Patent: US2018/153860, 2018, A1. Location in patent: Paragraph 0554; 0555

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol synthesis

496062-15-8
496062-16-9
Synthesis of 2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol from 4-Thiazoleaceticacid,2-bromo-5-methyl-,methylester(9CI)

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol Preparation Products And Raw materials

Raw materials

4-Thiazoleaceticacid,2-bromo-5-methyl-,methylester(9CI) Diisobutylaluminium hydride Dichloromethane Toluene Hydrochloric acid

Preparation Products

2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol Suppliers

Global Suppliers ( 22)
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc. +1(858) 699-3322 marketing@accelachem.com United States 6022 65
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39645 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 021-57520305 13795461237 zhuruyan@jskchem.com China 49221 58
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 9993 58
Hefei Molybdenum Kai Pharmaceutical Technology Co., Ltd 18001872185; 18001872185 690231469@qq.com China 18474 58
Supplier Advantage
Accela ChemBio Inc. 65
Amadis Chemical Company Limited 58
Aikon International Limited 58
Career Henan Chemica Co 58
Energy Chemical 58
Bide Pharmatech Ltd. 58
Bide Pharmatech Ltd. 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 58
Accela ChemBio Co.,Ltd. 58
Hefei Molybdenum Kai Pharmaceutical Technology Co., Ltd 58

496062-16-9 (2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol) Related Search:

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4-Thiazoleethanol,2-bromo-5-methyl- 2-BroMo-4-(2-hydroxyethyl)-5-Methylthiazole 2-(2-bromo-5-methylthiazol-4-yl)ethanol 2-(2-Bromo-5-methyl-1,3-thiazol-4-yl)ethanol 496062-16-9