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Lacidipine 13C8

Lacidipine 13C8 Structure
Lacidipine 13C8 structure
CAS No.
1261432-01-2
Chemical Name:
Lacidipine 13C8
Synonyms
Lacidipine 13C8;13C8]-Lacidipine;Lacidipine-[13C8] (Standard);Lacidipine 13C8Q: What is Lacidipine 13C8 Q: What is the CAS Number of Lacidipine 13C8 Q: What is the storage condition of Lacidipine 13C8 Q: What are the applications of Lacidipine 13C8
CBNumber:
CB48038285
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-04-18 09:52:20
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Lacidipine 13C8 Chemical Properties, Uses, Production

Uses

Lacidipine-13C8 is the deuterium labeled Lacidipine[1]. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[2][3].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Zhang A, et al. Lacidipine attenuates apoptosis via a caspase-3 dependent pathway in human kidney cells. Cell Physiol Biochem. 2013;32(4):1040-9.
[3] Cristofori P, et al. The calcium-channel blocker lacidipine reduces the development of atherosclerotic lesions in the apoE-deficient mouse. J Hypertens. 2000 Oct;18(10):1429-36. DOI:10.1097/00004872-200018100-00010

Lacidipine 13C8 Preparation Products And Raw materials

Raw materials

Preparation Products

Lacidipine 13C8 Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Manhag Testing Technology Co., Ltd 400-818 0104 18918165978 yanyan.guo@bestown.net.cn China 7770 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
Manhag Testing Technology Co., Ltd 58
SHANGHAI ZZBIO CO., LTD. 58
TargetMol 58

1261432-01-2 (Lacidipine 13C8) Related Search:

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Lacidipine 13C8 Lacidipine 13C8Q: What is Lacidipine 13C8 Q: What is the CAS Number of Lacidipine 13C8 Q: What is the storage condition of Lacidipine 13C8 Q: What are the applications of Lacidipine 13C8 13C8]-Lacidipine Lacidipine-[13C8] (Standard) 1261432-01-2