5-Hydroxy-1H-imidazole-4-carboxamide
- CAS No.
- 56973-26-3
- Chemical Name:
- 5-Hydroxy-1H-imidazole-4-carboxamide
- Synonyms
- AHM;Ampba;SL-1207;SM 108);Imazolipine MZB1;Bredinin aglycone;FF-10501-01 (FF-10501;SM-108【antitumor agent】;4-Carbamoylimidazolium-5-olate;4-carbamoyl-5-hydroxyimidazole
- CBNumber:
- CB4855000
- Molecular Formula:
- C4H5N3O2
- Molecular Weight:
- 127.1
- MDL Number:
- MFCD09753122
- MOL File:
- 56973-26-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 260°C |
|---|---|
| Boiling point | 575.0±35.0 °C(Predicted) |
| Density | 1.627 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Water (Slightly) |
| form | Solid |
| pka | 7.20±0.15(Predicted) |
| color | Grey |
| FDA UNII | U6IZ97918F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
5-Hydroxy-1H-imidazole-4-carboxamide price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-H943250-5G | 5-Hydroxy-3H-imidazole-4-carboxamide | 56973-26-3 | 5g | $1613 | 2026-06-03 | Buy |
| TRC | TRC-H943250-500MG | 5-Hydroxy-3H-imidazole-4-carboxamide | 56973-26-3 | 500mg | $205 | 2026-06-03 | Buy |
| ChemScene | CS-0024727 | Bredinin aglycone ≥98% | 56973-26-3 | 250mg | $50 | 2026-06-04 | Buy |
| ChemScene | CS-0024727 | Bredinin aglycone ≥98% | 56973-26-3 | 1g | $84 | 2026-06-04 | Buy |
| ChemScene | CS-0024727 | Bredinin aglycone ≥98% | 56973-26-3 | 5g | $391 | 2026-06-04 | Buy |
5-Hydroxy-1H-imidazole-4-carboxamide Chemical Properties, Uses, Production
Chemical Properties
Grey Solid
Uses
5-Hydroxy-3H-imidazole-4-carboxamide (cas# 56973-26-3) is a compound useful in organic synthesis.
Definition
ChEBI: A hydroxyimidazole that is 5-hydroxyimidazole in which the hydrogen at position 4 is replaced by an aminocarbonyl group.
Synthesis
66934-73-4
56973-26-3
Under nitrogen protection, 20.0 g of 5-hydroxy-1H-imidazole-4-carboxamide hydrochloride dihydrate prepared according to the method of Reference Example 2 was dissolved in 240 mL of a 0.45 mol/L hydrochloric acid solution, and heated to 50°C to dissolve it completely. Maintaining the reaction temperature at 50 °C, 40 mL of an aqueous solution containing 14.3 g of sodium formate was added slowly and dropwise over 35 minutes. Upon completion of the reaction, the reaction mixture was cooled to an internal temperature of 5 °C and stirring was continued for 90 minutes. The resulting crystals were collected by filtration, and the crystals were washed sequentially using a mixture comprising 20 mL of acetone and 40 mL of water and 60 mL of acetone, resulting in 12.6 g of 5-hydroxy-1H-imidazole-4-carboxamide-3/4 hydrate, the product being a pale yellow crystal. The water content of the product was 8.6% (determined by Karl Fischer method). Infrared spectra (ATR method) showed characteristic absorption peaks located at 1655, 1619, 1584, 1551 cm1. Powder X-ray diffraction pattern and infrared absorption spectra (ATR method) are demonstrated in Fig. 8, Table 3 and Fig. 9, respectively.
References
[1] Patent: EP2762469, 2014, A1. Location in patent: Paragraph 0144-0145
[2] Patent: US2015/51408, 2015, A1. Location in patent: Paragraph 0039
5-Hydroxy-1H-imidazole-4-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 |
View Latest Price from 5-Hydroxy-1H-imidazole-4-carboxamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-13 | Bredinin aglycone
56973-26-3
|
$29.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-25 | 5-Hydroxy-1H-imidazole-4-carboxamide
56973-26-3
|
$31.00 | 1ASSAYS | 99 | 10t | Henan Xiangtong Chemical Co., Ltd. |
-
- Bredinin aglycone
56973-26-3
- $29.00
- 99.88%
- TargetMol Chemicals Inc.
-
- 5-Hydroxy-1H-imidazole-4-carboxamide
56973-26-3
- $31.00
- 99
- Henan Xiangtong Chemical Co., Ltd.
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