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2-Amino-6-hydroxymethylpyrimidine

2-Amino-6-hydroxymethylpyrimidine Structure
2-Amino-6-hydroxymethylpyrimidine structure
CAS No.
2164-67-2
Chemical Name:
2-Amino-6-hydroxymethylpyrimidine
Synonyms
2-Aminopyrimidine-4-methanol;2-Bromo-8-methoxybenzoicacid;4-Pyrimidinemethanol, 2-amino-;(2-aminopyrimidin-4-yl)methanol;(2-azanylpyrimidin-4-yl)methanol;2-Amino-6-hydroxymethylpyrimidine;4-Pyrimidinemethanol, 2-amino- (7CI,8CI);2-Amino-6-hydroxymethylpyrimidine ISO 9001：2015 REACH;ETHYL3-(CYANOMETHYL)-2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLATE
CBNumber:
CB4969585
Molecular Formula:
C5H7N3O
Molecular Weight:
125.13
MDL Number:
MOL File:
2164-67-2.mol
MSDS File:
SDS
Last updated:2026-05-28 02:07:52
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2-Amino-6-hydroxymethylpyrimidine Properties

Melting point 145 °C
Boiling point 396.3±34.0 °C(Predicted)
Density 1.360±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 13.34±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338

2-Amino-6-hydroxymethylpyrimidine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS43574 (2-Aminopyrimidin-4-yl)methanol 98% 2164-67-2 1g $221 2026-06-04 Buy
Activate Scientific AS43574 (2-Aminopyrimidin-4-yl)methanol 98% 2164-67-2 5g $602 2026-06-04 Buy
Matrix Scientific 295557 (2-Aminopyrimidin-4-yl)methanol 2164-67-2 250.00mg $58 2026-05-19 Buy
Matrix Scientific 295557 (2-Aminopyrimidin-4-yl)methanol 2164-67-2 1.00g $169 2026-05-19 Buy
Matrix Scientific 295557 (2-Aminopyrimidin-4-yl)methanol 2164-67-2 5.00g $452 2026-05-19 Buy
Product number Packaging Price Buy
AS43574 1g $221 Buy
AS43574 5g $602 Buy
295557 250.00mg $58 Buy
295557 1.00g $169 Buy
295557 5.00g $452 Buy

2-Amino-6-hydroxymethylpyrimidine Chemical Properties, Uses, Production

Synthesis

4-PyriMidinecarboxylic acid, 2-aMino-, Methyl ester

2164-66-1

2-Amino-6-hydroxymethylpyrimidine

2164-67-2

General procedure for the synthesis of 2-amino-4-hydroxymethylpyrimidine from methyl 2-aminopyrimidine-4-carboxylate: 2-amino-4-methoxycarbonylpyrimidine (3.0 g, 20 mmol) was suspended in a solvent mixture of ethanol (150 mL) and dichloromethane (20 mL), followed by addition of sodium borohydride (2.2 g, 59 mmol). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, acetone (20 mL) was added slowly under cooling in an ice bath, followed by dropwise addition of 2M hydrochloric acid until no bubbles were produced. The pH of the reaction mixture was adjusted to 8 with saturated aqueous sodium bicarbonate and the precipitated solid was collected by filtration. The filtrate was concentrated under reduced pressure, suspended in 10% methanol-chloroform solution and filtered through silica gel (5.0 g). The filtrate was evaporated under reduced pressure and the residue was recrystallized from ethyl acetate to give 1.8 g of 2-amino-4-hydroxymethylpyrimidine as a light yellow solid (yield: 73%). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ 4.30 (s, 2H), 5.35 (s, 1H), 6.48 (s, 2H), 6.65 (d, J = 4.9 Hz, 1H), 8.19 (d, J = 4.9 Hz, 1H).

References

[1] Patent: EP1864977, 2007, A1. Location in patent: Page/Page column 17

2-Amino-6-hydroxymethylpyrimidine synthesis

2164-66-1
2164-67-2
Synthesis of 2-Amino-6-hydroxymethylpyrimidine from 4-PyriMidinecarboxylic acid, 2-aMino-, Methyl ester

2-Amino-6-hydroxymethylpyrimidine Preparation Products And Raw materials

Raw materials

4-Dimethoxymethylpyrimidin-2-ylamine 4-PyriMidinecarboxylic acid, 2-aMino-, Methyl ester Hydrochloric acid Sodium borohydride Water
Sodium bicarbonate Dichloromethane Acetone Ethanol

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Preparation Products

2-Amino-6-hydroxymethylpyrimidine Suppliers

Global Suppliers ( 61)
Supplier Tel Email Country ProdList Advantage
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56
Shanghai Chiral bio-compound co., Ltd. 021-5068 3667/17749785980/1029026415; 17749785980 1029026415@qq.com China 4501 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
Suzhou Nuoouman Biological Technology Co., Ltd. 15026866316 180642609@qq.com China 4966 58
Shandong utilizing biological technology co., LTD 18669728830 15966937598 3407650895@qq.com China 5183 58
Supplier Advantage
Nanjing Chemlin Chemical Co., Ltd 64
Shandong Xiya Chemical Co., Ltd 57
Shanghai yirong biology science and technology co., ltd 60
Bide Pharmatech Ltd. 60
DebyeTec.com Inc. 56
Shanghai Chiral bio-compound co., Ltd. 58
Amadis Chemical Company Limited 58
Aikon International Limited 58
Suzhou Nuoouman Biological Technology Co., Ltd. 58
Shandong utilizing biological technology co., LTD 58

View Latest Price from 2-Amino-6-hydroxymethylpyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-6-hydroxymethylpyrimidine pictures 2026-08-20 2-Amino-6-hydroxymethylpyrimidine
2164-67-2
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

2-Amino-6-hydroxymethylpyrimidine Spectrum

2-Amino-6-hydroxymethylpyrimidine(2164-67-2)1HNMR

2164-67-2 (2-Amino-6-hydroxymethylpyrimidine) Related Search:

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4-(1-[(1-Phenyl-1H-1,2,4-triazol-3-yl)oxy]ethyl)-2-pyrimidinamine 4-[1-(2,4-Dichlorophenoxy)ethyl]-2-pyrimidinamine 4-(1-Phenoxyethyl)-2-pyrimidinamine

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2-Amino-6-hydroxymethylpyrimidine 4-Pyrimidinemethanol, 2-amino- (7CI,8CI) (2-aminopyrimidin-4-yl)methanol (2-azanylpyrimidin-4-yl)methanol 2-Aminopyrimidine-4-methanol 4-Pyrimidinemethanol, 2-amino- 2-Amino-6-hydroxymethylpyrimidine ISO 9001：2015 REACH 2-Bromo-8-methoxybenzoicacid ETHYL3-(CYANOMETHYL)-2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLATE 2164-67-2 PYRIMIDINE