ChemicalBook >> CAS DataBase List >>Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]-

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]-

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- structure

CAS No.: 1628784-54-2

Chemical Name:: Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]-

Synonyms: BG47;BG-47;BG 47;Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]-

CBNumber:: CB49797794

Molecular Formula:: C25H22N4O2S

Molecular Weight:: 442.53

MDL Number:

MOL File:: 1628784-54-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:33

Request For Quotation

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- Properties

Boiling point	586.1±50.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
pka	8.61±0.48(Predicted)

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- Chemical Properties, Uses, Production

Description

BG47 is a novel probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light.

Uses

BG47 is a prototypical histone deacetylases HDAC1 and HDAC2 selective, optoepigenetic probe. BG47 can bind to and competitively inhibits the deacetylase activity of HDAC targets upon a light-induced trans-to-cis isomerization, and increases Histone Methyltransferase H3K9 acetylation. BG47 can be used for neurological disease research[1].

IC 50

HDAC1; HDAC2

References

[1] Reis SA, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes. Nat Chem Biol. 2016 May;12(5):317-23. DOI:10.1038/nchembio.2042

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- Suppliers

Global Suppliers ( 2)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

1628784-54-2 (Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]-) Related Search:

Carbamazepine UNC-0642 4-Phenylbutyric acid DS-3201 Entinostat

MRTX-1719

1of2

Benzamide, 4-[2-[4-(dimethylamino)phenyl]diazenyl]-N-[2-hydroxy-5-(2-thienyl)phenyl]- BG 47 BG47 BG-47 1628784-54-2