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ChemicalBook >> CAS DataBase List >>2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo-

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo-

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- Structure
2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- structure
CAS No.
2136579-33-2
Chemical Name:
2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo-
Synonyms
AKR1B10-IN-1;N-(3-(4-Fluorophenyl)propyl)-7-hydroxycoumarin-3-carboxamide;2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo-
CBNumber:
CB49826063
Molecular Formula:
C19H16FNO4
Molecular Weight:
341.33
MDL Number:
MOL File:
2136579-33-2.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:23
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2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- Properties

Boiling point 640.8±55.0 °C(Predicted)
Density 1.357±0.06 g/cm3(Predicted)
form Solid
pka 7.48±0.20(Predicted)
color White to yellow

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0254065 AKR1B10-IN-1 95.0% 2136579-33-2 5mg $412 2026-06-04 Buy
ChemScene CS-0254065 AKR1B10-IN-1 95.0% 2136579-33-2 10mg $661 2026-06-04 Buy
ChemScene CS-0254065 AKR1B10-IN-1 95.0% 2136579-33-2 25mg $1330 2026-06-04 Buy
ChemScene CS-0254065 AKR1B10-IN-1 95.0% 2136579-33-2 50mg $2123 2026-06-04 Buy
ChemScene CS-0254065 AKR1B10-IN-1 95.0% 2136579-33-2 100mg $3196 2026-06-04 Buy
Product number Packaging Price Buy
CS-0254065 5mg $412 Buy
CS-0254065 10mg $661 Buy
CS-0254065 25mg $1330 Buy
CS-0254065 50mg $2123 Buy
CS-0254065 100mg $3196 Buy

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- Chemical Properties, Uses, Production

Uses

AKR1B10-IN-1 is a potent inhibitor of AKR1B10 (Aldo-Keto Reductase 1B10) with an IC50 of 3.5 nM. AKR1B10-IN-1 suppresses proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells[1].

References

[1] Endo S, et al. Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells [published correction appears in J Med Chem. 2018 Feb 8;61(3):1380] DOI:10.1021/acs.jmedchem.7b00830

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 2793 58
Shanghai Merlot Chemical Co., LTD 15821661757 226174156@qq.com China 476 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Sichuan BioCrick Biotech Co., Ltd 28-86-28-8543-3893 13260669172 sales@biocrick.com China 5020 58
Supplier Advantage
BioBioPha Co., Ltd. 58
Shanghai Merlot Chemical Co., LTD 58
TargetMol Chemicals Inc. 58
Sichuan BioCrick Biotech Co., Ltd 58

2136579-33-2 (2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo-) Related Search:

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2H-1-Benzopyran-3-carboxamide, N-[3-(4-fluorophenyl)propyl]-7-hydroxy-2-oxo- AKR1B10-IN-1 N-(3-(4-Fluorophenyl)propyl)-7-hydroxycoumarin-3-carboxamide 2136579-33-2