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ChemicalBook >> CAS DataBase List >>4,4,4-Trifluoro-3-oxo-butyric acid

4,4,4-Trifluoro-3-oxo-butyric acid

4,4,4-Trifluoro-3-oxo-butyric acid Structure
4,4,4-Trifluoro-3-oxo-butyric acid structure
CAS No.
400-36-2
Chemical Name:
4,4,4-Trifluoro-3-oxo-butyric acid
Synonyms
4,4,4-trifluoro-3-oxobutanoic acid;4,4,4-Trifluoro-3-oxo-butyric acid;Butanoic acid, 4,4,4-trifluoro-3-oxo-
CBNumber:
CB51010508
Molecular Formula:
C4H3F3O3
Molecular Weight:
156.06
MDL Number:
MOL File:
400-36-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:02
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4,4,4-Trifluoro-3-oxo-butyric acid Properties

Boiling point 189.6±40.0 °C(Predicted)
Density 1.519
storage temp. 2-8°C
pka 0.83±0.32(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4,4,4-Trifluoro-3-oxo-butyric acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 299862 4,4,4-Trifluoro-3-oxobutanoic acid 400-36-2 50.00mg $132 2026-05-19 Buy
Matrix Scientific 299862 4,4,4-Trifluoro-3-oxobutanoic acid 400-36-2 100.00mg $221 2026-05-19 Buy
Matrix Scientific 299862 4,4,4-Trifluoro-3-oxobutanoic acid 400-36-2 250.00mg $358 2026-05-19 Buy
aablocks AA0037FE 4,4,4-TRIFLUORO-3-OXOBUTYRIC ACID 95% 400-36-2 50mg $91 2026-05-28 Buy
aablocks AA0037FE 4,4,4-TRIFLUORO-3-OXOBUTYRIC ACID 95% 400-36-2 100mg $154 2026-05-28 Buy
Product number Packaging Price Buy
299862 50.00mg $132 Buy
299862 100.00mg $221 Buy
299862 250.00mg $358 Buy
AA0037FE 50mg $91 Buy
AA0037FE 100mg $154 Buy

4,4,4-Trifluoro-3-oxo-butyric acid Chemical Properties, Uses, Production

Synthesis

Butanoyl chloride, 4,4,4-trifluoro-3-oxo-

2261-53-2

4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID

400-36-2

Example 5: Reaction (ReacSO-1) To a 1,2-dichloroethane solution (758 g) of crude 4,4,4-trifluoro-3-oxobutanoyl chloride (ca. 1.29 mol) was added slowly and dropwise over a period of 2 hr. to a dioxane solution (214 g) containing 1.29 mol of water (23.3 g), at -40°C to -20°C. Upon completion of the reaction, the concentration of the enolized form of compound (II-II) in the resulting solution (981 g) was determined to be 19 wt% by 1H NMR analysis (with cyclobutanesulfone as the internal standard), which corresponded to a yield of 92%.

References

[1] Patent: WO2015/4035, 2015, A1. Location in patent: Page/Page column 15

4,4,4-Trifluoro-3-oxo-butyric acid Preparation Products And Raw materials

Raw materials

Butanoyl chloride, 4,4,4-trifluoro-3-oxo- Ethyl 4,4,4-trifluoroacetoacetate 1,4-Dioxane 1,2-Dichloroethane

Preparation Products

6-methoxy-4-(trifluoromethyl)-1H-quinolin-2-one

4,4,4-Trifluoro-3-oxo-butyric acid Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4534 58
Nanjing BAM Biomedical Technology Co., Ltd. 18066080842 13952020641 bamd@foxmail.com China 774 55
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
Shaanxi Dideu Medichem Co. Ltd +86-29-81139210 17389186172 1077@dideu.com China 3999 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 15811073878 sales@peking-pharmacy.com China 9999 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 13761987713; 13761987713 hxzheng@sunwaypharm.cn China 9905 58
shanghai jinquzheshengwuyiyao 1 17717547976@163.com China 1935 58
Shijiazhuang Yansheng Biotechnology Co., LTD 18332018567; 18332018567 331860441@qq.com China 3375 58
Alchem Pharmtech,Inc. 8485655694 sales@alchempharmtech.com United States 63645 58
Supplier Advantage
Mashilabs (Shanghai) Co.,Ltd. 58
Nanjing BAM Biomedical Technology Co., Ltd. 55
Aikon International Limited 58
CONIER CHEM AND PHARMA LIMITED 58
Shaanxi Dideu Medichem Co. Ltd 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 58
shanghai jinquzheshengwuyiyao 58
Shijiazhuang Yansheng Biotechnology Co., LTD 58
Alchem Pharmtech,Inc. 58

View Latest Price from 4,4,4-Trifluoro-3-oxo-butyric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID pictures 2026-08-07 4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID
400-36-2
 $1.00-3.00 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd

400-36-2 (4,4,4-Trifluoro-3-oxo-butyric acid) Related Search:

Isopropyl 4,4,4-trifluoroacetoacetate Ethyl 2-methyl-4,4,4-trifluoroacetoacetate Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate Ethyl 4,4,4-trifluoroacetoacetate Ethyl 2-chloro-4,4,4-trifluoroacetoacetate
Methyl 4,4,4-trifluoroacetoacetate 4,4,4-Trifluoro-acetoacetic acid tert-butyl ester Ethyl 4,4,4-trifluoro-2-methoxy-3-oxobutyrate 4,4,4-Trifluoro-2-hydroxylimino-3-oxobutyric acid ethyl ester Ethyl 4,4,4-trifluoro-2-(triphenylphosphoranylidene)acetoacetate
Ethyl 3-([2-acetyl-5-(tert-butyl)-3-thienyl]amino)-2-(2,2,2-trifluoroacetyl)acrylate Ethyl 2-(2,6-dichlorobenzyl)-4,4,4-trifluoroacetoacetate α-Trifluoroacetyl-G-butyrolactone Methyl 2-([2-(ethoxycarbonyl)-4,4,4-trifluoro-3-oxobut-1-enyl]amino)thiophene-3-carboxylate Methyl 4-([2-(ethoxycarbonyl)-4,4,4-trifluoro-3-oxobut-1-enyl]amino)thiophene-3-carboxylate
Methyl 2-([2-(ethoxycarbonyl)-4,4,4-trifluoro-3-oxobut-1-enyl]amino)benzoate 4,4,4-Trifluoro-3-oxo-2-(phenylhydrazono)butyric acid ethyl ester Ethyl trifluoroacetylbromoacetate

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4,4,4-trifluoro-3-oxobutanoic acid Butanoic acid, 4,4,4-trifluoro-3-oxo- 4,4,4-Trifluoro-3-oxo-butyric acid 400-36-2