1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI)
- CAS No.
- 171919-36-1
- Chemical Name:
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI)
- Synonyms
- 1-methylpyrrolo[2,3-b]pyridine-3-carbaldehyde;1-Methy-1H-Pyrrolo[2,3-b]pyridine-3-carbaldehyde;1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde;1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl-;1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 97%;1-Methyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde(WX624086);1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI)
- CBNumber:
- CB51089885
- Molecular Formula:
- C9H8N2O
- Molecular Weight:
- 160.17
- MDL Number:
- MFCD11054209
- MOL File:
- 171919-36-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | OR301278 | 250mg | $21 |
| 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | OR301278 | 1g | $24 |
| 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | OR301278 | 5g | $81 |
| 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | OR301278 | 25g | $392 |
| 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | OR301278 | 100g | $1559 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| HS Code | 2933399990 |
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI) price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR301278 | 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | 171919-36-1 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR301278 | 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | 171919-36-1 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR301278 | 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | 171919-36-1 | 5g | $81 | 2026-06-04 | Buy |
| Apolloscientific | OR301278 | 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | 171919-36-1 | 25g | $392 | 2026-06-04 | Buy |
| Apolloscientific | OR301278 | 1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde >98% | 171919-36-1 | 100g | $1559 | 2026-06-04 | Buy |
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI) Chemical Properties,Uses,Production
Synthesis
27257-15-4
68-12-2
171919-36-1
b) Synthesis of 1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde: Phosphorus trichloride (1.2 g, 7.9 mmol) was slowly added dropwise to 10 mL of N,N-dimethylformamide at 0 °C with stirring. After the dropwise addition, stirring was continued for 10 minutes. Subsequently, a solution of 1-methyl-7-azaindole (0.95 g, 7.2 mmol) dissolved in 5 mL of N,N-dimethylformamide was added over 1 min. The reaction mixture was stirred at 0°C for 1 hour, followed by warming to 60°C and continued stirring for 30 minutes. Upon completion of the reaction, the mixture was poured into water, adjusted to alkaline with aqueous sodium bicarbonate and extracted three times with ethyl acetate. The organic layers were combined, washed with water, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was obtained as 0.85 g in 74% yield, and the purity met the requirements of the subsequent reaction.1H NMR (300MHz, CDCl3) δ: 9.99 (s, 1H), 8.55 (m, 1H), 8.44 (m, 1H), 7.84 (s, 1H), 7.27 (m, 1H), 3.97 (s, 3H).
References
[1] Chemical and pharmaceutical bulletin, 1995, vol. 43, # 8, p. 1351 - 1357
[2] Patent: WO2005/66132, 2005, A1. Location in patent: Page/Page column 66
[3] Heteroatom Chemistry, 2011, vol. 22, # 2, p. 148 - 157
[4] Patent: WO2009/3003, 2008, A2. Location in patent: Page/Page column 61-62
[5] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 3, p. 1201 - 1212
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1267 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19981 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2998 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1396 | 59 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
View Lastest Price from 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2019-12-23 | 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI)
171919-36-1
|
1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
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- 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 1-methyl- (9CI)
171919-36-1
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
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