MGC97209
- CAS No.
- Chemical Name:
- MGC97209
- Synonyms
- CAR;FIH;MB67;CXAR;EIG8;HHC1;HCAR;hCasR;NSHPT;GPRC2A
- CBNumber:
- CB51135366
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
MGC97209 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP2147 | CAR-LBD (101-348), GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE) | 10μg | $415 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SRP2146 | CAR, GST tagged, human recombinant, expressed in E. coli, ≥70% (SDS-PAGE) | 10 μg | $415 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SRP2067 | CAR, ligand binding domain (101-348) human recombinant, expressed in E. coli, ≥85% (SDS-PAGE) | 10μg | $488 | 2025-07-31 | Buy |
MGC97209 Chemical Properties, Uses, Production
Uses
The gene encoding this protein is localized on human chromosome 1q23.3.
Biological Activity
The constitutive androstane receptor (CAR) was identified as a member of the orphan nuclear hormone receptor family in 1994. Although constitutively active, it can be further activated by `phenobarbitol-like` compounds, the most potent being the synthetic compound TCPOBOP. Upon activation, CAR regulates the xenobiotic drug metabolizing enzymes, cytochrome P450s. There are several overlapping functions between the nuclear receptors PXR and CAR. Recently, CAR, as well as PXR, have been shown to place a role in bile acid clearance and cholestatic liver injury.
MGC97209 Preparation Products And Raw materials
Raw materials
Preparation Products
MGC97209 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xinyu Biotechnology Co., Ltd | 13301728348 | 13301728348@163.com | China | 8000 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Xinyu Biotechnology Co., Ltd | 58 |
