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(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Structure
(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL structure
CAS No.
58577-87-0
Chemical Name:
(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL
Synonyms
SERINOL(BZL);H-SER(BZL)-OL;H-D-SER(BZL)-OL;Ser(bzl)-OL.HCL;Serinol(Bzl)·HCl;H-Ser(Bzl)-ol.HCl;O-BENZYL-L-SERINOL;O-BENZYL-D-SERINOL;H-L-Ser(Bzl)-ol·HCl;L-Serinol(Bzl) hydrochloride
CBNumber:
CB5115532
Molecular Formula:
C10H15NO2
Molecular Weight:
181.23
MDL Number:
MFCD00235943
MOL File:
58577-87-0.mol
Last updated:2026-01-13 11:15:47
Product description Number Pack Size Price
(R)-(+)-2-Amino-3-benzyloxy-1-propanol 97% 473758 1g $105
(R)-(+)-2-Amino-3-benzyloxy-1-propanol A600205 1g $95
(2R)-(+)-2-Amino-3-(benzyloxy)propan-1-ol OR40517 5g $428
O-Benzyl-L-serinolhydrochloride,98%(HPLC) 98%(HPLC) 03219 5G $168
O-Benzyl-L-serinolhydrochloride,≥98%(HPLC) ≥98%(HPLC) 03219 250MG $36.22
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(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Properties

Melting point 34-37 °C (lit.)
Boiling point 307 °C (lit.)
Density 1.0918 (rough estimate)
refractive index 1.5464 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
pka 12.53±0.10(Predicted)
form Oil
color Clear Colourless
optical activity [α]20/D +4°, c = 1 in methylene chloride
Sensitive Air Sensitive
InChI InChI=1S/C10H15NO2/c11-10(6-12)8-13-7-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2/t10-/m1/s1
InChIKey ZJUOMDNENVWMPL-SNVBAGLBSA-N
SMILES C(O)[C@@H](N)COCC1=CC=CC=C1
UNSPSC Code 12352112
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C
Risk Statements  34
Safety Statements  26-27-36/37/39-45
RIDADR  3267
WGK Germany  3
HazardClass  8
HS Code  29221990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
NFPA 704
1
3 0

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 473758 (R)-(+)-2-Amino-3-benzyloxy-1-propanol 97% 58577-87-0 1g $105 2023-06-20 Buy
TRC A600205 (R)-(+)-2-Amino-3-benzyloxy-1-propanol 58577-87-0 1g $95 2021-12-16 Buy
Apolloscientific OR40517 (2R)-(+)-2-Amino-3-(benzyloxy)propan-1-ol 58577-87-0 5g $428 2021-12-16 Buy
Chem-Impex 03219 O-Benzyl-L-serinolhydrochloride,98%(HPLC) 98%(HPLC) 58577-87-0 5G $168 2021-12-16 Buy
Chem-Impex 03219 O-Benzyl-L-serinolhydrochloride,≥98%(HPLC) ≥98%(HPLC) 58577-87-0 250MG $36.22 2021-12-16 Buy
Product number Packaging Price Buy
473758 1g $105 Buy
A600205 1g $95 Buy
OR40517 5g $428 Buy
03219 5G $168 Buy
03219 250MG $36.22 Buy

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Chemical Properties,Uses,Production

Chemical Properties

Colorless to yellow liquid or low melting solid

Uses

(R)-(+)-2-Amino-3-benzyloxy-1-propanol is used as a reagent to synthesize beta-amino alcohols, compounds that are used as therapeutic agents to treat heart disease. (R)-(+)-2-Amino-3-benzyloxy-1-propanol is also used as a reagent to synthesize 15-membered macrolide antibiotics, drugs that are used to treat respiratory tract infections.

Synthesis

O-BENZYL-L-SERINE

4726-96-9

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL

58577-87-0

General procedure for the synthesis of O-benzyl-L-serinol from (S)-2-amino-3-(benzyloxy)propionic acid: O-benzyl-L-serine (15.0 g, 76.8 mmol) was slowly added to a tetrahydrofuran (THF, 150 mL) suspension of lithium aluminum hydride (4.37 g, 115.3 mmol) under reflux conditions. The reaction mixture was stirred at reflux temperature for 1.5 h. After cooling in an ice bath, distilled water (4.4 mL), 10% NaOH aqueous solution (4.4 mL), and distilled water (4.4 mL) were added sequentially. After stirring for 18 h at room temperature, the mixture was filtered and the filter cake was washed with THF. The filtrate was concentrated under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography (eluent ratio CHCl3/MeOH/NH4OH = 10:1:0.1) to afford the target product, O-benzyl-L-serinol (6.43 g, 69% yield), as a colorless foamy substance. Its physical properties were as follows: [α]27D -5.0 (c 0.760, methanol); 1H NMR (CDCl3) δ 7.27-7.41 (m, 5H), 4.53 (s, 2H), 3.39-3.67 (m, 4H), 3.03-3.17 (m, 1H), 1.85 (br s, 3H); 13C NMR (CDCl3) δ 137.9, 128.2, 127.55, 127.50, 73.1, 72.5, 63.7, 52.3; MS (ESI) m/z 182.2 [M + H]+. The NMR data are in agreement with literature reports.

References

[1] Liebigs Annalen der Chemie, 1988, p. 851 - 854
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5787 - 5801
[3] Tetrahedron, 2002, vol. 58, # 46, p. 9387 - 9401
[4] Tetrahedron, 1975, vol. 31, p. 2629 - 2632
[5] Molecules, 2009, vol. 14, # 12, p. 5124 - 5143

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Preparation Products And Raw materials

Raw materials

O-BENZYL-L-SERINE Tetrahydrofuran Lithium Aluminum Hydride Sodium hydroxide

Preparation Products

1-Propanol, 2-[bis(phenylmethyl)amino]-3-(phenylmethoxy)-, (2R)-

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Suppliers

Global( 100)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8617390183901 cynthia@enlaibio.com China 1098 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Sichuan Jiaying Lai Technology Co.,LTD 		18716376478 ycling@enlaibio.com CHINA 302 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 19894 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
Shenzhen Nexconn Pharmatechs Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Sichuan Jiaying Lai Technology Co.,LTD 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
Dideu Industries Group Limited 		58

View Lastest Price from (R)-2-AMINO-3-BENZYLOXY-1-PROPANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-L-Ser(Bzl)-OL.HCl pictures 2026-01-22 H-L-Ser(Bzl)-OL.HCl
58577-87-0
 US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL pictures 2025-12-01 (R)-2-AMINO-3-BENZYLOXY-1-PROPANOL
58577-87-0
 US $0.00 / kg 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
H-Ser(Bzl)-Ol.HCl pictures 2020-01-06 H-Ser(Bzl)-Ol.HCl
58577-87-0
 US $1.00 / g 1g 98% 100KG Sichuan Jiaying Lai Technology Co.,LTD

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL Spectrum

(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL(58577-87-0)1HNMR(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL(58577-87-0)IR

58577-87-0((R)-2-AMINO-3-BENZYLOXY-1-PROPANOL)Related Search:

BENZYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE 3-FLUORO-5-(TRIFLUOROMETHYL)PHENOL O-BENZYL-L-SERINE Boc-Thr(Bzl)-OH Z-SER(BZL)-OH
FMOC-SER(BZL)-OH N-Boc-(S)-2-amino-3-benzyloxy-1-propanol 3-Benzyloxy-1-propanol Benzyl 2-AcetaMido-2-deoxy-3-O-(β-D-galactopyranosyl) α-D-galactopyranoside L-THREONINE BENZYL ESTER
BOC-SER(P-CHLORO-BZL)-OH DCHA BENZYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE BENZYL 2-ACETAMIDO-2-DEOXY-3,6-DI-O-ACETYL-ALPHA-D-GLUCOPYRANOSIDE BOC-THR(BZL)-ONP AC-ALPHA-BENZYL-4,6-O-BENZYLIDENE-MURAMIC ACID
BENZYL-2-ACETAMIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSIDE BOC-SER(BZL)-OSU BOC-THR(P-CHLORO-BZL)-OH DCHA

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O-BENZYL-D-SERINOL O-BENZYL-L-SERINOL SERINOL(BZL) (R)-(+)-2-AMINO-3-BENZYLOXY-1-PROPANOL (R)-2-AMINO-3-BENZYLOXY-1-PROPANOL H-D-SER(BZL)-OL H-SER(BZL)-OL Serinol(Bzl)·HCl (R)-(+)-2-Amino-3-benzyloxy-1-propanol,97% (R)-(+)-2-AMino-3-benzyloxy-1-propanol, 98+% (R)-2-Amino-3-(benzyloxy)propan-1-ol H-Ser(Bzl)-ol.HCl H-L-Ser(Bzl)-ol·HCl L-Serinol(Bzl) hydrochloride O-Benzyl-L-serinol hydrochloride≥ 98% (HPLC) (2R)-(+)-2-Amino-3-(benzyloxy)propan-1-ol 1-Propanol, 2-amino-3-(phenylmethoxy)-, (2R)- (R)-2-AMINO-3-BENZYLOXY-1-PROPANOL USP/EP/BP (2R)-2-amino-3-phenylmethoxypropan-1-ol (R)-(+)-2-Amino-3-benzyloxy-1-propanol Ser(bzl)-OL.HCL 58577-87-0 C6H5CH2OCH2CHNH2CH2OH Amino Alcohols Chiral Building Blocks Asymmetric Synthesis Organic Building Blocks Amino Alcohols Chiral Building Blocks Organic Building Blocks